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CHAPTER 42 ■ Modern Modes of Ventilation in the Operating Room 723<br />

but because those areas of atelectasis, whatever the age of the<br />

patient, contain lung units with prolonged time constants, it is<br />

likely that long periods of high pressure will be required. Direct<br />

observation in neonates and infants undergoing thoracotomy<br />

suggests that long and repeated inspiratory pressures in excess of<br />

20 cmH 2<br />

O are frequently required to reverse areas of atelectasis<br />

from lung compression.<br />

The use of continuous positive airway pressure (CPAP) during<br />

induction has also been shown to prevent atelectasis in adults; in<br />

children, its continued use during spontaneous ventilation may<br />

minimize the formation of atelectasis. 46,47 Patients with tracheo -<br />

malacia are particularly prone to airway collapse and will also<br />

benefit from CPAP. 48 The routine use of CPAP during spontaneous<br />

ventilation with either an ETT or an LMA should also assist in<br />

minimizing the work of breathing by increasing lung volumes<br />

and restoring these to the more efficient part of the pressurevolume<br />

curve.<br />

DESIGN PRINCIPLES OF<br />

MECHANICAL VENTILATORS<br />

Anesthesia ventilators have undergone significant advances since<br />

the late 1990s, changing from being adjuncts or add-ons to the<br />

anesthesia machine to their current position as a prominent and<br />

integral part of the modern anesthesia work station. In parallel,<br />

advances in electronics and microprocessing have led to a number<br />

of advanced features that were limited to intensive care unit (ICU)<br />

ventilators now being available and integrated into anesthesia<br />

ventilators. Thus, more modes of ventilation are available to the<br />

practicing anesthetist in the operating room setting. The speed<br />

of these changes afforded by advances in technology mean that<br />

software updates can be applied to existing anesthesia systems<br />

to improve their function without necessarily requiring replace -<br />

ment of the whole anesthesia machine. Different manufacturers<br />

incorporate different technology into their anesthesia machines<br />

and these models frequently change, so general principles rather<br />

than details of specific machines are discussed whenever possible.<br />

At the same time, practice in ICUs has been moving toward pro -<br />

viding respiratory support augmenting or assisting patients’<br />

breathing rather than completely replacing it, as is the case with<br />

controlled ventilation. Philosophically, the same approach can<br />

now be applied to anesthetized patients if paralysis is not required<br />

for the surgical procedure.<br />

There is no single classification system for ventilators, but<br />

they can be classified according to their power source, drive<br />

mechanism, cycling mechanism, and bellows type. In addition,<br />

anesthesia ventilators may be described as single-circuit or doublecircuit<br />

depending on whether there is a separate gas supply to<br />

power the bellows independent from the gas flowing in the patient<br />

circuit. The power source provides the energy necessary to operate<br />

a mechanical ventilator and is usually electrical or pneumatic.<br />

Many older pneumatic ventilators required only a source of<br />

compressed gas to function. Most contemporary ventilators,<br />

however, require an electrical or electrical plus pneumatic power<br />

source. The drive system provides the actual force required to<br />

generate the gas flow, and in the operating room setting, this<br />

requires a pressure gradient to be developed between the ventilator<br />

and the lungs. They also require a mechanism to provide<br />

variable PEEP.<br />

Double-circuit and Single-circuit Systems<br />

Most anesthesia machine ventilators can be classified as doublecircuit,<br />

pneumatically driven ventilators, but this is changing.<br />

In the double-circuit system, the driving force (i.e., compressed<br />

gas) compresses a bag or bellows, which then delivers gas to the<br />

patient. The driving gas can be either 100% oxygen or a mixture<br />

of oxygen and air.<br />

Some newer anesthesia systems are classified as singlecircuit,<br />

piston-driven, and electronically controlled with fresh gas<br />

decoupling (FGD). The important difference with these systems from<br />

traditional anesthesia circle systems is that, rather than having<br />

separate circuits for the patient gas and drive gas, there is only a single<br />

gas circuit for the patient. The piston functions in the same way as<br />

the plunger of a syringe and can be set to deliver a predetermined<br />

VT or airway pressure to the patient. This type of ventilator uses a<br />

computer-controlled stepper motor rather than compressed gas to<br />

generate gas flow within the circuit. These systems also incorporate<br />

a feature known as fresh gas decoupling (FGD), which is required<br />

for the safe functioning of the systems and is described in Monitor -<br />

ing the System: FGF Compensation, Compliance Compensation.<br />

Although both types of system are widely used in pediatric<br />

practice, the single-circuit, piston-driven anesthesia breathing<br />

systems may perform more reliably when used at high frequencies<br />

and in pressure-control mode likely to be used with neonates and<br />

infants. 49<br />

Bellows<br />

Bellows can be classified by the direction of movement during the<br />

expiratory phase into ascending and descending bellows. As the<br />

names suggest, ascending bellows ascend during the expiratory<br />

phase, whereas descending (hanging) bellows, descend during the<br />

expiratory phase. Most modern electronic ventilators using a<br />

bellows system have an ascending design that is inherently safer<br />

because these bellows do not fill if a total disconnection occurs.<br />

Descending bellows, however, may continue to fill during discon -<br />

nection because, although the driving gas pushes the bellows<br />

upward during the inspiratory phase, during the expiratory phase,<br />

the weight of the bellows as they descend may entrain air into the<br />

breathing system. The situation has become more complicated<br />

recently because some of the new anesthesia systems have incor -<br />

porated descending bellows as part of their FGD system. The<br />

operating principles of ascending bellows in a traditional system<br />

are shown in Figure 42–8, with the ventilator relief valve shown to<br />

the right of the bellows. During the inspiratory phase, the driving<br />

gas entering the bellows chamber causes the pressure within it to<br />

increase, which closes the ventilator relief valve and forces the<br />

anesthetic gas within the bellows into the lungs. During the<br />

expiratory phase, the driving gas exits the bellows chamber and<br />

the pressure within declines to zero. This allows the ventilator<br />

relief valve to open and the gas exhaled by the patient to fill the<br />

bellows and be exhaled via the ventilator relief valve. Gas flows<br />

preferentially to fill the bellows before being scavenged through<br />

the ventilator relief valve, by utilizing a weighted ball in the<br />

ventilator relief valve that produces 2 to 3 cm of back pressure.<br />

This design means that all ascending bellows ventilators produce<br />

2 to 3 cm of PEEP within the circuit, whether PEEP is set on the<br />

machine or not. This is not enough, however, to prevent atelectasis<br />

with controlled ventilation. Scavenging occurs only during the<br />

expiratory phase when the ventilator relief valve is open. Oxygen

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