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2 Introduction<br />
2.1 Colorectal Cancer<br />
2.2 Symptoms<br />
2.3 Epidemiology<br />
2.4 Pathophysiology<br />
2.4.1 Histology<br />
2.4.2 Genetic Basis<br />
2.4.3 Etiology of Colorectal Cancer<br />
2.5 Diagnosis<br />
2.5.1 Digital Rectal Examination<br />
2.5.2 Fecal Occult Blood Test<br />
2.5.3 Flexible Sigmoidoscopy<br />
2.5.4 Colonoscopy<br />
2.5.5 Virtual Colonoscopy<br />
2.5.6 Double Contrast Barium Enema<br />
2.6 Prognosis and Disease Staging<br />
2.7 Treatment Options<br />
2.7.1 Surgery and Radiation Therapy<br />
2.7.2 Chemotherapy<br />
2.7.3 Targeted Therapies<br />
2.7.4 Resistance to Pharmacological Therapies<br />
2.7.5 Treatment Guidelines<br />
2.8 GBI Research Report Guidance