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Testicular Cancer - Department of Surgery at SUNY Downstate ...

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Risk Factors<br />

www.downst<strong>at</strong>esurgery.org<br />

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Undescended testis (cryptorchidism) – 4-8 fold increased risk<br />

- Orchiopexy<br />

Genetics – Klinefelter syndrome, Down’s syndrome<br />

Family history <strong>of</strong> testis cancer – 1.4% have family history; risk <strong>of</strong><br />

testicular cancer increases 4-6 fold in sons and siblings<br />

Personal history – 1-2% p<strong>at</strong>ients with testicular cancer will develop a<br />

second primary tumor in contral<strong>at</strong>eral testis<br />

Environment – DES, Agent Orange, solvents<br />

Activities – horseback and motorcycle riding, local trauma, and<br />

increased scrotal temper<strong>at</strong>ure (are not)

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