Testicular Cancer - Department of Surgery at SUNY Downstate ...
Testicular Cancer - Department of Surgery at SUNY Downstate ...
Testicular Cancer - Department of Surgery at SUNY Downstate ...
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Summary<br />
www.downst<strong>at</strong>esurgery.org<br />
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<strong>Testicular</strong> cancer is an uncommon but highly tre<strong>at</strong>able cancer<br />
Germ-cell tumors comprise >95% <strong>of</strong> testicular cancers<br />
Tumors with seminoma histology but with elev<strong>at</strong>ed AFP are<br />
considered nonseminomas<br />
Seminomas are radiosensitive and respond well to pl<strong>at</strong>in-based<br />
chemotherapy<br />
Most common route <strong>of</strong> disease dissemin<strong>at</strong>ion is via the lymph<strong>at</strong>ic<br />
channels from the primary tumor to retroperitoneal lymph nodes<br />
Retroperitoneal lymph node dissection is an effective therapy for<br />
p<strong>at</strong>ients with high-risk clinical stage I nonseminom<strong>at</strong>ous germ cell<br />
cancer.