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Testicular Cancer - Department of Surgery at SUNY Downstate ...

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Summary<br />

www.downst<strong>at</strong>esurgery.org<br />

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<strong>Testicular</strong> cancer is an uncommon but highly tre<strong>at</strong>able cancer<br />

Germ-cell tumors comprise >95% <strong>of</strong> testicular cancers<br />

Tumors with seminoma histology but with elev<strong>at</strong>ed AFP are<br />

considered nonseminomas<br />

Seminomas are radiosensitive and respond well to pl<strong>at</strong>in-based<br />

chemotherapy<br />

Most common route <strong>of</strong> disease dissemin<strong>at</strong>ion is via the lymph<strong>at</strong>ic<br />

channels from the primary tumor to retroperitoneal lymph nodes<br />

Retroperitoneal lymph node dissection is an effective therapy for<br />

p<strong>at</strong>ients with high-risk clinical stage I nonseminom<strong>at</strong>ous germ cell<br />

cancer.

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