Testicular Cancer - Department of Surgery at SUNY Downstate ...
Testicular Cancer - Department of Surgery at SUNY Downstate ...
Testicular Cancer - Department of Surgery at SUNY Downstate ...
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www.downst<strong>at</strong>esurgery.org<br />
Serum tumor markers<br />
<br />
<br />
<br />
<br />
Alpha-fetoprotein (AFP) – elev<strong>at</strong>ed in 40-60% <strong>of</strong> men with<br />
nonseminomas; seminomas do not produce AFP<br />
β-hCG – elev<strong>at</strong>ion seen in 14% <strong>of</strong> p<strong>at</strong>ients with stage I seminoma<br />
and 50% <strong>of</strong> p<strong>at</strong>ients with metast<strong>at</strong>ic seminoma; 40-60% <strong>of</strong> men with<br />
nonseminoma have elev<strong>at</strong>ed levels<br />
LDH – elev<strong>at</strong>ed in both but with less clear prognostic significance<br />
Measured before and after surgery
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