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Absite Review Series: Adrenal Gland Disorders

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www.downstatesurgery.org<br />

Mineralocorticoids<br />

Renin-angiotensin-aldosterone axis is<br />

responsive to delivery of sodium to the DCT<br />

Low sodium delivery triggers release of<br />

renin from JGA<br />

• Shock<br />

• Renal artery vasoconstriction<br />

• Hyponatremia<br />

Renin cleaves angiotensinogen (liver) to<br />

angiotensin-1<br />

ACE (lungs) cleaves to angiotensin-2

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