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5 Alpha Reductase Inhibitors (5ARI)<br />

blocks conversion of testosterone to<br />

dihydrotestosterone, thereby inhibiting prostate growth<br />

Drug<br />

Finasteride 5 mg daily<br />

Dutasteride 0.5 mg daily<br />

5 mg daily<br />

0.5 mg daily<br />

Dosage<br />

§ Poten?al side effects <br />

– Diminished ejaculatory volume <br />

– Erec?le dysfunc?on <br />

– Decreased libido <br />

– Gynecomas?a <br />

– Increase risk of high grade CaP <br />

Physician’s Desk Reference, 64 ed. Montvale, NJ:Thomson PDR; 2010.<br />

Andriole G, et al. J Urol. 2004;172:399-403. PMID: 15371854.

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