slide deck (pdf) - CME Outfitters
slide deck (pdf) - CME Outfitters
slide deck (pdf) - CME Outfitters
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Clinical Management<br />
STEP 3a: Addition of an<br />
antimuscarinic or beta-3 agonist<br />
If the patient has symptoms of both<br />
obstruction and irritation as well as bother<br />
! In multiple studies the combination of antimuscarinics were<br />
more efficacious in reducing voiding frequency, nocturia, or<br />
IPSS compared to α-blockers or placebo alone.<br />
! The β3 agonist class is newly available and has not been<br />
studied in combination with an AB.<br />
! Neither antimuscarinics or β3 agonists have been studied<br />
in combinations with PDE5i medications.<br />
Oelke M, et al. Eur Urol. 2013;64(1):118-140. PMID: 23541338.<br />
Rosenberg MT, et al. Publication pending.