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Phosphodiesterase type 5 Inhibitors for use in BPH-LUTS Medication Dose Indication Tadalafil 2.5 mg per day BPH Tadalafil 5.0 mg per day BPH and ED Common side effects: headache, back pain, dizziness, flushing and dyspepsia. Contraindicated in patients who use nitrates, potassium channel openers, or non-selective 2nd generation Abs. Cardiac status must be assessed for patient risk before taking this medications. 1.Roehrborn CG, et al. J Urol. 2008;180(4):1228-1234. PMID: 18722631. 2.Oelke M, et al. Eur Urol. 2013;64(1):118-140. PMID: 23541338. 3.Nehra A, et al. Mayo Clin Proc. 2012;87(8):766-778. PMID: 22862865.

Rosenberg MT, et al. Publication Pending The Next STEP: Step 3

Phosphodiesterase type 5<br />

Inhibitors for use in BPH-LUTS<br />

Medication Dose Indication<br />

Tadalafil 2.5 mg per day BPH<br />

Tadalafil 5.0 mg per day BPH and ED<br />

Common side effects: headache, back pain, dizziness, flushing and dyspepsia.<br />

Contraindicated in patients who use nitrates, potassium channel openers, or<br />

non-selective 2nd generation Abs. Cardiac status must be assessed for patient<br />

risk before taking this medications.<br />

1.Roehrborn CG, et al. J Urol. 2008;180(4):1228-1234. PMID: 18722631.<br />

2.Oelke M, et al. Eur Urol. 2013;64(1):118-140. PMID: 23541338.<br />

3.Nehra A, et al. Mayo Clin Proc. 2012;87(8):766-778. PMID: 22862865.

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