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Predominant Symptoms<br />

! The enlarged gland has been proposed to contribute to<br />

the overall lower urinary tract symptoms (LUTS)<br />

complex via at least two routes:<br />

! (1) direct bladder outlet obstruction (BOO) from enlarged<br />

tissue (static component)<br />

! (2) from increased smooth muscle tone and resistance within<br />

the enlarged gland (dynamic component)<br />

! Voiding symptoms have often been attributed to the<br />

physical presence of BOO. Detrusor overactivity is<br />

thought to be a contributor to the storage symptoms<br />

seen in LUTS<br />

McVary KT, et al. J Urol. 2011;185(5):1793-1803. PMID: 21420124

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