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BPH, LUTS, and BOO Complex Interrelationships All Men >40 y Histologic BPH BOO LUTS BOO, bladder outlet obstruction; LUTS, lower urinary tract symptoms. Emberton M, et al. Int J Clin Pract. 2008;62(7):1076-1086. PMID: 18479366; Roehrborn CG. Rev Urol. 2005;7(Suppl 9):S3-S14. PMID: 16985902; Roehrborn CG. Med Clin N Am. 2011;95(1):87-100. PMID: 21095413.
Predominant Symptoms ! The enlarged gland has been proposed to contribute to the overall lower urinary tract symptoms (LUTS) complex via at least two routes: ! (1) direct bladder outlet obstruction (BOO) from enlarged tissue (static component) ! (2) from increased smooth muscle tone and resistance within the enlarged gland (dynamic component) ! Voiding symptoms have often been attributed to the physical presence of BOO. Detrusor overactivity is thought to be a contributor to the storage symptoms seen in LUTS McVary KT, et al. J Urol. 2011;185(5):1793-1803. PMID: 21420124
Page 1 and 2: Gaining Ground in Men’s Genitouri
Page 3 and 4: Accreditation This program has been
Page 5 and 6: Learning Objectives ! Explain the s
Page 7 and 8: Matt T. Rosenberg, MD Disclosures S
Page 9 and 10: Disclosures ! Faculty of this CE ac
Page 11 and 12: Get Social with Us CMEOutfitters.co
Page 13 and 14: Georgia Association of Physician As
Page 15 and 16: Matt T. Rosenberg, MD Disclosures S
Page 17 and 18: In what percentage of your patients
Page 19 and 20: Function of the Prostate Normal Fun
Page 21: Benign Prostatic Hyperplasia ! A co
Page 25 and 26: Definition of OAB International Con
Page 27 and 28: How to differentiate the etiology o
Page 29 and 30: Common Comorbidities in BPH-LUTS Co
Page 31 and 32: Audience Response Question Fact: ED
Page 33 and 34: BPH-LUTS and ED Common Pathophysiol
Page 35 and 36: What to Keep in Mind in the Evaluat
Page 37 and 38: The Evaluation of LUTS: History, Ph
Page 39 and 40: Medications Can Cause or Exacerbate
Page 41 and 42: Laboratory Tests ! Urinalysis ! Inf
Page 43 and 44: Audience Response Question The most
Page 45 and 46: The Purpose of the Voiding Diary !
Page 47 and 48: Rosenberg MT, et al. Publication Pe
Page 49 and 50: STEP 1: Informed Surveillance If th
Page 51 and 52: Clinical Management Step2a: Alpha B
Page 53 and 54: Clinical Management Step2b: Phospho
Page 57 and 58: Antimuscarinics - Immediate Release
Page 59 and 60: ! Dry Mouth ! Constipation ! Headac
Page 61 and 62: Beta 3 Agonists Drug Mirabegron Dos
Page 63 and 64: Clinical Management Step3b: Adding
Page 65 and 66: 5 Alpha Reductase Inhibitors (5ARI)
Page 69 and 70: Clinical Connections: Summary ! Tre

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