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Research Week Abstract Book - Northern Health

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Chronic Disease Management<br />

APProPriaTE OR NOT? A SURVEY OF ANTIMICrobial PresCribinG AT THE<br />

NORThern HOSPITal<br />

Chhanabhai A 1 , Hume S 2 , Jeremiah C 2 , Yeung L 1 .<br />

1<br />

Pharmacy Department, <strong>Northern</strong> <strong>Health</strong><br />

CHROnIC DISEASE Management<br />

2<br />

Department of Medicine, <strong>Northern</strong> <strong>Health</strong><br />

Background<br />

Antimicrobial resistance is a growing problem globally, and is compounded by a lack of new antimicrobials in the drug<br />

development pipeline. There is good evidence that regional antimicrobial resistance rates correlate with corresponding<br />

regional antimicrobial consumption. Up to 50% of antimicrobials used in hospitals in Australia and overseas are considered<br />

inappropriate and are associated with adverse patient outcomes, while also driving resistance.<br />

Aim<br />

To conduct a baseline survey of antimicrobial prescribing trends at The <strong>Northern</strong> Hospital (TNH) and identify areas that could<br />

be targeted for quality improvement through <strong>Northern</strong> <strong>Health</strong>’s antimicrobial stewardship program.<br />

Methodology<br />

Two teams, each consisting of an infectious diseases physician and a pharmacist, reviewed the charts of randomly selected<br />

inpatients throughout TNH. When the patient was prescribed an antimicrobial, the team reviewed the patient’s notes and<br />

pathology investigations and assessed the appropriateness of the antimicrobial. Where possible, the Australian Therapeutic<br />

Guidelines: Antibiotic Version 14 was used as the reference standard.<br />

Results<br />

Thirty of 80 (37.5%) patients surveyed were on at least one antimicrobial. The indication for the antimicrobial was documented<br />

in 24 (80%) patients. In thirteen patients (43.3%), the prescribed antimicrobial was considered inappropriate. Categories of<br />

inappropriate antimicrobial prescribing included: antimicrobials not indicated, inappropriately broad-spectrum antimicrobials<br />

and extension of surgical prophylaxis beyond 24 hours.<br />

Conclusion<br />

The results show there are a number of areas in which the prescribing of antimicrobials can be improved to optimise patient<br />

outcomes while minimising unintended consequences of antimicrobial use. These areas will provide targets for future<br />

antimicrobial stewardship activities within the hospital.<br />

21

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