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New Drug Update 2010-2011 Faculty Disclaimer - CME Conferences

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2 nd Annual Essentials in Primary Care<br />

Fall Conference<br />

Friday, November 11, <strong>2011</strong><br />

Azilsartan medoxomil - Edarbi<br />

First ARB in combination with chlorthalidone pending<br />

FDA approval<br />

Change in systolic blood pressure:<br />

End point<br />

Clinic SBP<br />

(change from baseline, mm<br />

Hg)<br />

Change in 24-h mean SBP<br />

(change from baseline, mm<br />

Hg)<br />

Azilsartan<br />

Chlorthalidon<br />

e<br />

40/25 (n=355)<br />

Azilsartan<br />

Chlorthalidone<br />

80/25 (n=352)<br />

Olmesartan<br />

HCTZ<br />

40/25 (n=364)<br />

- 42.5 - 44.0 - 37.1

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