New Drug Update 2010-2011 Faculty Disclaimer - CME Conferences

2 nd Annual Essentials in Primary Care
Fall Conference
Friday, November 11, 2011
Dronedarone - Multaq
• DIONYSOS Trial evaluating the efficacy and safety of
dronedarone versus amiodarone for the
maintenance of sinus rhythm in 504 patients with
persistent Atrial Fibrillation (AF) for a short
treatment duration (mean follow up of 7 months).
– AF recurrence or premature drug discontinuation for
intolerance or lack of efficacy). There were 184 patients
(73.9%) who reached the primary endpoint in the
dronedarone arm as compared to 141 (55.3%) in the
amiodarone arm (p