New Drug Update 2010-2011 Faculty Disclaimer - CME Conferences
New Drug Update 2010-2011 Faculty Disclaimer - CME Conferences
New Drug Update 2010-2011 Faculty Disclaimer - CME Conferences
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2 nd Annual Essentials in Primary Care<br />
Fall Conference<br />
Friday, November 11, <strong>2011</strong><br />
Liraglutide – Victoza<br />
Pancreatitis: Warnings and Precautions<br />
• In five clinical trials including more than 3,900<br />
people, there were seven cases of pancreatitis in<br />
patients using liraglutide and one case in a patient<br />
using another diabetes medicine. This constituted a<br />
4:1 imbalance of pancreatitis cases, when<br />
considering the number of patient exposures (2.2 vs.<br />
0.6 cases per 1000 patient-years).<br />
• Patients taking liraglutide should be aware of the<br />
symptoms of pancreatitis, such as severe abdominal<br />
pain that may also radiate into the back, possibly<br />
with nausea, and vomiting.<br />
Liraglutide – Victoza<br />
Adverse Effects in Clinical Trials %__<br />
• Nausea 28.4<br />
• Diarrhea 17.1<br />
• Vomiting 10.9<br />
• Constipation 9.9<br />
• Upper Respiratory Tract Infection 9.5<br />
Wayne Weart<br />
<strong>New</strong> <strong>Drug</strong> <strong>Update</strong> Part I