Influence of the Processes Parameters on the Properties of The ...

Chapter 2.
<strong>Processes</strong> to Manufacture Foams and to Functionalize <strong>the</strong> Surface
well as <strong>the</strong> resistance to water <strong>of</strong> <strong>the</strong> material, not only from <strong>the</strong> improvement <strong>of</strong> <strong>the</strong> dispersion homogeneity
<strong>of</strong> <strong>the</strong> filler in <strong>the</strong> matrix, but also thanks to a modification <strong>of</strong> <strong>the</strong> interface quality.
6 Conclusion
Different processes for manufacturing scaffolds were discussed in detail with advantages and
disadvantages. Scaffolds obtained by each technique posses typical structure and morphology and can be
used as per requirement. Scaffolds for tissue engineering should encourage <strong>the</strong> growth, migration, and
organization <strong>of</strong> cells, providing support while <strong>the</strong> tissue is forming <strong>the</strong> scaffolds will be replaced with host
cells and a new extracellular matrix which in turn should provide functional and mechanical properties,
similar to native tissue. The material and <strong>the</strong> 3-D structure <strong>of</strong> scaffolds have a significant effect on cellular
activity. Depending on <strong>the</strong> tissue <strong>of</strong> interest and <strong>the</strong> specific application, <strong>the</strong> required scaffold material and
its properties will be quite different. Gas foaming technique to manufacture scaffolds discussed with
reference to kinetics and <strong>the</strong>rmodynamic approach. Diffusion, plasticization <strong>of</strong> polymer, nucleation and
desorption phenomena <strong>the</strong>ory play an important role during scaffold forming by gas foaming. The
experimental results obtained by this technique will be discussed extensively in <strong>the</strong> later chapters.
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