Influence of the Processes Parameters on the Properties of The ...
Influence of the Processes Parameters on the Properties of The ...
Influence of the Processes Parameters on the Properties of The ...
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Chapter 2.<br />
<str<strong>on</strong>g>Processes</str<strong>on</strong>g> to Manufacture Foams and to Functi<strong>on</strong>alize <str<strong>on</strong>g>the</str<strong>on</strong>g> Surface<br />
well as <str<strong>on</strong>g>the</str<strong>on</strong>g> resistance to water <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>the</str<strong>on</strong>g> material, not <strong>on</strong>ly from <str<strong>on</strong>g>the</str<strong>on</strong>g> improvement <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>the</str<strong>on</strong>g> dispersi<strong>on</strong> homogeneity<br />
<str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>the</str<strong>on</strong>g> filler in <str<strong>on</strong>g>the</str<strong>on</strong>g> matrix, but also thanks to a modificati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>the</str<strong>on</strong>g> interface quality.<br />
6 C<strong>on</strong>clusi<strong>on</strong><br />
Different processes for manufacturing scaffolds were discussed in detail with advantages and<br />
disadvantages. Scaffolds obtained by each technique posses typical structure and morphology and can be<br />
used as per requirement. Scaffolds for tissue engineering should encourage <str<strong>on</strong>g>the</str<strong>on</strong>g> growth, migrati<strong>on</strong>, and<br />
organizati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> cells, providing support while <str<strong>on</strong>g>the</str<strong>on</strong>g> tissue is forming <str<strong>on</strong>g>the</str<strong>on</strong>g> scaffolds will be replaced with host<br />
cells and a new extracellular matrix which in turn should provide functi<strong>on</strong>al and mechanical properties,<br />
similar to native tissue. <strong>The</strong> material and <str<strong>on</strong>g>the</str<strong>on</strong>g> 3-D structure <str<strong>on</strong>g>of</str<strong>on</strong>g> scaffolds have a significant effect <strong>on</strong> cellular<br />
activity. Depending <strong>on</strong> <str<strong>on</strong>g>the</str<strong>on</strong>g> tissue <str<strong>on</strong>g>of</str<strong>on</strong>g> interest and <str<strong>on</strong>g>the</str<strong>on</strong>g> specific applicati<strong>on</strong>, <str<strong>on</strong>g>the</str<strong>on</strong>g> required scaffold material and<br />
its properties will be quite different. Gas foaming technique to manufacture scaffolds discussed with<br />
reference to kinetics and <str<strong>on</strong>g>the</str<strong>on</strong>g>rmodynamic approach. Diffusi<strong>on</strong>, plasticizati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> polymer, nucleati<strong>on</strong> and<br />
desorpti<strong>on</strong> phenomena <str<strong>on</strong>g>the</str<strong>on</strong>g>ory play an important role during scaffold forming by gas foaming. <strong>The</strong><br />
experimental results obtained by this technique will be discussed extensively in <str<strong>on</strong>g>the</str<strong>on</strong>g> later chapters.<br />
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