Just add Cognis! - Anshul Life Sciences
Just add Cognis! - Anshul Life Sciences
Just add Cognis! - Anshul Life Sciences
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<strong>Just</strong> <strong>add</strong><br />
<strong>Cognis</strong>!<br />
ier2.indd 1 18/08/08 17:43
<strong>Just</strong> <strong>add</strong><br />
<strong>Cognis</strong>!<br />
ier2.indd 2 18/08/08 17:43
COGNIS IN BRIEF<br />
As a global supplier of natural-source<br />
ingredients to promote healthy nutrition<br />
and well-being, <strong>Cognis</strong> Nutrition & Health<br />
has an ongoing commitment to help its<br />
customers lead their markets by meeting<br />
consumer demands for innovative ‘wellness’<br />
products.<br />
The company offers decades of experience<br />
backed by exemplary customer service,<br />
and a full range of high quality ingredients<br />
for these markets:<br />
Functional foods and beverages<br />
Food supplements<br />
Clinical and infant nutrition<br />
Pharmaceutical industry<br />
Food industry<br />
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<strong>Cognis</strong> Nutrition & Health provides<br />
innovative and market-oriented<br />
formulations and applications, including<br />
concepts geared to growth markets like<br />
body composition, heart health, brain<br />
health and eye health. Add value to your<br />
products with the marketable health<br />
claims associated with our scientificallyproven<br />
ingredients.<br />
The portfolio of antioxidants, plant extracts<br />
and specialty lipids for functional foods<br />
and food supplements includes:<br />
Omevital TM -High purity omega-3 marine oils<br />
Tonalin® * - Conjugated linoleic acid<br />
Vegapure® - Plant sterols and sterol esters<br />
Xangold® - Natural lutein esters<br />
Betatene® - Natural mixed carotenoids<br />
Natural beta-carotene<br />
Covitol® - Natural-source vitamin E<br />
Covi-ox® - Natural mixed tocopherols<br />
Delios® - Medium-chain triglycerides<br />
Plantalin TM - Standardized plant extracts<br />
All of our products are natural-source,<br />
science-based and safe.<br />
<strong>Cognis</strong> Nutrition & Health is a business unit<br />
of the <strong>Cognis</strong> Group, which<br />
employs about 7,600 people,<br />
and operates production<br />
sites and service centers in 30<br />
countries.<br />
* Tonalin® CLA is an exclusively<br />
licensed product of the <strong>Cognis</strong> Group.<br />
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OMEVITAL TM<br />
Omega-3 fatty acids<br />
Concepts<br />
Specific age group related concepts for<br />
heart, brain and eye health<br />
Specific age group related concepts against<br />
inflammatory and dry skin<br />
Active ingredients<br />
Long-chain fatty acids EPA and DHA<br />
Source<br />
High quality marine oils from sustainable<br />
sources<br />
Health benefits<br />
Variety of health benefits, especially for the<br />
heart and the brain<br />
Applications authorized in the EC<br />
Food supplements<br />
Foods and beverages<br />
EC Regulatory status<br />
Joint Health Claims Initiative (JHCI)<br />
health claim: “Eating 3 gram<br />
weekly, or 0.45 gram daily, long<br />
chain omega-3 polyunsaturated<br />
fatty acids, as part of a healthy<br />
lifestyle helps maintain heart<br />
health.”<br />
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Clinical research<br />
Numerous clinical studies scientifically<br />
demonstrate the effectiveness of marine<br />
omega-3 fatty acids EPA and DHA in relation<br />
to cardiovascular diseases. In <strong>add</strong>ition, several<br />
studies have been published that support an<br />
important role for omega-3 fatty acids in brain<br />
health and other health benefits.<br />
Forms and applications<br />
Product<br />
Omevital TM<br />
18/12 TG Ultra*<br />
Omevital TM<br />
11/18 TG Ultra*<br />
Omevital TM<br />
33/22 TG*<br />
Omevital TM<br />
33/22 TG Ultra*<br />
Omevital TM<br />
33/22 EE*<br />
Omevital TM<br />
45/10 TG*<br />
Omevital TM<br />
45/10 TG Ultra*<br />
Omevital TM<br />
10/50 TG*<br />
Omevital TM<br />
10/50 TG*<br />
Omevital TM<br />
18/12 TG<br />
Gold<br />
Form<br />
Oil<br />
Oil<br />
Oil<br />
Oil<br />
Oil<br />
Oil<br />
Oil<br />
Oil<br />
Oil<br />
Oil<br />
Minimum EPA/DHA<br />
(as TG)<br />
Min. 160 mg/g EPA<br />
Min. 100 mg/g DHA<br />
Min. 90 mg/g EPA<br />
Min. 150 mg/g DHA<br />
Min. 300 mg/g EPA<br />
Min. 200 mg/g DHA<br />
Min. 300 mg/g EPA<br />
Min. 200 mg/g DHA<br />
Min. 300 mg/g EPA<br />
Min. 200 mg/g DHA<br />
Min. 400 mg/g EPA<br />
Min. 100 mg/g DHA<br />
Min. 400 mg/g EPA<br />
Min. 100 mg/g DHA<br />
Min. 100 mg/g EPA<br />
Min. 440 mg/g DHA<br />
Min. 100 mg/g EPA<br />
Min. 440 mg/g DHA<br />
Min. 160 mg/g EPA<br />
Min. 100 mg/g DHA<br />
Application<br />
Food<br />
supplements<br />
Food<br />
supplements<br />
Food<br />
supplements<br />
Food<br />
supplements<br />
Food<br />
supplements<br />
Food<br />
supplements<br />
Food<br />
supplements<br />
Food<br />
supplements<br />
Food<br />
supplements<br />
Spreads and<br />
butter<br />
Milk and fermented<br />
milk<br />
Milk analogues<br />
Baked goods<br />
Chewable<br />
supplements<br />
*All products are available in bulk (oil and softgel<br />
capsules) and finished bottles.<br />
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TONALIN®<br />
Conjugated linoleic acid<br />
Concept<br />
Body composition<br />
Active isomers<br />
C18 : 2 c9, t11 and C18 : 2 t10, c12<br />
in 50 : 50 ratio<br />
Source<br />
Safflower oil<br />
Health benefits<br />
Reduces body fat mass<br />
Maintains lean body mass<br />
Prevents weight regain<br />
Applications authorized in the EC<br />
Food supplements<br />
EC Regulatory status<br />
When used in food supplements, does not<br />
fall under the scope of Novel Food.<br />
<strong>Cognis</strong> has applied for Novel Food approval<br />
for Tonalin® CLA in functional food.<br />
Application process is on-going.<br />
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Clinical research<br />
Long-term studies have confirmed the benefits of<br />
Tonalin® CLA for healthy body composition, with daily<br />
supplementation helping to safely reduce body fat mass<br />
(BFM) while protecting lean body mass (LBM). 17 clinical<br />
studies with Tonalin® and body composition have been<br />
published. Major clinical studies using Tonalin® include:<br />
Laso et al, 2007, 3.0 g CLA/day in 500 ml milk, 12 weeks<br />
Roman et al, 2007, 3.0 g CLA/day in milk, 4 months<br />
Watras et al, 2006, 3.2 g CLA/day, 6 months<br />
Gaullier et al, 2005, 3.4 g CLA/day, 24 months<br />
Gaullier et al, 2004, 3.4 g CLA/day, 12 months<br />
Kamphuis et al, 2003, 1.8 and 3.6 g CLA/day, 13 weeks<br />
Thom et al, 2001, 1.8 g CLA/day, 12 weeks<br />
Riserus et al, 2001, 4.2 g CLA/day, 4 weeks<br />
Smedman et al, 2001, 4.2 g CLA/day, 12 weeks<br />
Berven et al, 2000, 3.5 g CLA/day, 12 weeks<br />
Blankson et al, 2000, 1.7, 3.4, 5.1 and 6.8 g CLA/day, 12<br />
weeks<br />
Forms and applications<br />
Product<br />
Concentration<br />
Form<br />
Application<br />
Tonalin® FFA<br />
80<br />
780 to 840<br />
mg/g<br />
Oil, free<br />
fatty acids<br />
Softgels<br />
Tonalin® SG<br />
500/750/<br />
1000T FFA<br />
Tonalin® TG 80<br />
Tonalin® 35<br />
WDP<br />
Tonalin® 40<br />
WDP<br />
500, 750 or<br />
1000 mg<br />
700 to 800<br />
mg/g<br />
320 to 380<br />
mg/g<br />
340 to 390<br />
mg/g<br />
Soft gel<br />
capsules<br />
Oil, Triglycerides<br />
Powder<br />
Powder<br />
Softgels<br />
Softgels<br />
Drinks*<br />
Dairy products*<br />
Bars*<br />
Powder mixes<br />
and Beverages*<br />
Capsules<br />
Powder mixes<br />
and Powders*<br />
Tonalin® 60<br />
WDP<br />
530 to 620<br />
mg/g<br />
Powder<br />
Capsules<br />
Powder mixes<br />
and Powders*<br />
* Novel Food notification for use in fortified foods is pending.<br />
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VEGAPURE®<br />
Plant sterols and plant sterol esters<br />
Concept<br />
Heart health<br />
Source<br />
Plant sources<br />
Health benefits<br />
Proven to lower cholesterol<br />
Applications authorized in the EC<br />
Yellow fat spreads<br />
Milk- and yogurt-type products<br />
Soya drinks<br />
Cheese-type products<br />
Salad dressings, mayonnaise and spicy sauces<br />
Rye bread<br />
Rice drinks<br />
EC Regulatory status<br />
Vegapure® range may be used in all authorized<br />
novel food applications as mentioned<br />
above. The use of plant sterols in food<br />
supplements does not fall under<br />
the scope of the Novel Food<br />
Regulation.<br />
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Clinical research<br />
Numerous clinical studies have shown<br />
that regular consumption of sterol esters<br />
significantly lowers LDL cholesterol (by up to<br />
15%) and improves the HDL/LDL ratio.<br />
Forms and applications<br />
Product Form Application<br />
Vegapure®<br />
95 E<br />
Esters -<br />
viscous oil<br />
Foods<br />
Vegapure® 67<br />
WDP E<br />
Vegapure®<br />
FTE<br />
Vegapure® F<br />
40 WDP E<br />
Esters -<br />
water-dispersible<br />
powder<br />
Free sterols<br />
- powder<br />
Free sterols -<br />
water-dispersible<br />
powder<br />
Foods<br />
Foods and<br />
Supplements<br />
Foods and<br />
Supplements<br />
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XANGOLD®<br />
Natural lutein<br />
esters<br />
Concepts<br />
Eye health<br />
Beauty-from-within<br />
Source<br />
Marigold<br />
(Tagetes erecta)<br />
Health benefits<br />
Helps to maintain healthy vision (into old<br />
age) - data suggests benefits for eye health<br />
with a daily lutein intake of around 6 mg<br />
Constituent of the Macular Pigment, which<br />
protects the retina against light damage<br />
Antioxidant<br />
A daily lutein intake of 10 mg may help to<br />
maintain a healthy skin<br />
Applications authorized in the EC<br />
Food supplements<br />
Food products - as food colorant<br />
EC Regulatory status<br />
Non-Novel Food status for food supplements<br />
Approved as food colorant (E161b)<br />
As legislation on functional food has<br />
yet to be harmonized in the EU,<br />
lutein esters as food fortifying<br />
ingredients are currently<br />
subject to country-specific laws<br />
and regulations.<br />
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Clinical Research<br />
Many studies suggest that antioxidants,<br />
particularly the carotenoids lutein<br />
and zeaxanthin, may help to prevent<br />
degenerative eye diseases such as cataracts<br />
and age-related macular degeneration<br />
(AMD). There is scientific evidence that<br />
these carotenoids also help maintain a<br />
healthy skin.<br />
Forms and applications<br />
Product<br />
Xangold® 15% OLV<br />
Xangold® 30% OLV<br />
Xangold® 37% MCT<br />
Oil<br />
Form<br />
Application<br />
Softgels<br />
Lipophilic<br />
matrices<br />
Xangold® 10%<br />
Beadlets<br />
Xangold® 10% GFB*<br />
Xangold® 20%<br />
Powder<br />
(beadlets)<br />
Tablets<br />
and Capsules<br />
Xangold® 8% WDP<br />
* gelatin free beadlets<br />
Water-dispersible<br />
powder<br />
Instant drink<br />
mixes<br />
Effervescent<br />
tablets<br />
References<br />
Trieschmann et al, 2007<br />
Palombo et al, 2007<br />
Koh et al, 2004<br />
Bone et al, 2003<br />
Heinrich et al, 2003<br />
Berendschott et al, 2000<br />
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BETATENE®<br />
BETATENE®<br />
Natural mixed carotenoids<br />
Natural beta-carotene<br />
Concepts<br />
Beauty-from-within / sun protection<br />
Antioxidant / pro-vitamin A<br />
Contains<br />
Mix of 5 natural carotenoids<br />
Rich in natural beta carotene<br />
Source<br />
Micro-alga: Dunaliella salina<br />
Health benefits<br />
Pro-vitamin A<br />
Antioxidant<br />
Helps maintain healthy skin<br />
Helps minimise sun-induced erythema<br />
Helps support a healthy immune system<br />
Applications authorized in the EC<br />
Food color<br />
Food supplements<br />
Food products<br />
Animal nutrition<br />
EC Regulatory status<br />
Authorized food color E160a<br />
according to 95/45/EC<br />
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Forms and applications<br />
Product Form Application<br />
Betatene® 30% OLIVE Oil<br />
Softgels<br />
Betatene® 30% MCT<br />
Food<br />
Betatene® 30% SOY<br />
supplements<br />
Betatene® 20% OLIVE<br />
Lipophilic<br />
matrices<br />
Betatene® 10% N<br />
Betatene® 7.5% N<br />
Microencapsulated<br />
powder<br />
(beadlets)<br />
Tablets and<br />
Capsules<br />
Food<br />
supplements<br />
Betatene® 2.5% WDP N<br />
Betatene® 1% CWD N<br />
Waterdispersible<br />
powder<br />
Food products<br />
Food color<br />
Food supplements<br />
Natural beta-carotene<br />
30% OLIVE<br />
20% OLIVE<br />
Oil<br />
Food products<br />
Food color<br />
Algro Natural Powder Animal<br />
nutrition<br />
Kosher, Halal and IP versions available.<br />
References<br />
Köpcke and Krutmann, 2008<br />
Watzel et al, 2003<br />
Wood et al, 2000<br />
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COVITOL®<br />
COVITOL®<br />
Natural-source<br />
vitamin E<br />
Concepts<br />
Beauty-from-within<br />
Antioxidant<br />
Active ingredient<br />
d-alpha tocopherol (acetate/succinate)<br />
Source<br />
Vegetable oil distillate<br />
Health benefits<br />
Antioxidant - the body’s most important<br />
lipophilic antioxidant<br />
Protects cell membranes from oxidative<br />
damage<br />
Promotes healthy immune responses<br />
Helps maintain healthy brain function<br />
Helps maintain healthy skin<br />
Helps maintain good health as we age<br />
Applications authorized in the EC<br />
Food supplements<br />
Food products: drinks, cereals, dairy products,<br />
bars<br />
Sports nutrition<br />
Infant nutrition<br />
EC Regulatory status<br />
Authorized source of vitamin E according<br />
to:<br />
Regulation 1925/2006 (Fortified<br />
Foods)<br />
Directive 2002/46/EC (Food<br />
Supplements)<br />
Directive 89/398/EEC, as amended<br />
(Foods for particular nutritional<br />
purposes)<br />
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Forms and applications<br />
Product<br />
Form<br />
Application<br />
d-alpha<br />
tocopherol<br />
Covitol®<br />
F-1000-2 EU<br />
Oil<br />
Softgels<br />
Lipophilic<br />
matrices<br />
Covitol®<br />
F-1300 EU<br />
Oil<br />
Softgels<br />
Lipophilic<br />
matrices<br />
Covitol®<br />
700 EU<br />
Powder<br />
Tablets<br />
Capsules<br />
d-alpha<br />
tocopherol<br />
acetate<br />
Covitol®<br />
700 WD EU<br />
Covitol®<br />
1100 EU<br />
Waterdispersible<br />
powder<br />
Oil<br />
Powder<br />
mixes<br />
Softgels<br />
Lipophilic<br />
matrices<br />
Covitol®<br />
1250 EU<br />
Oil<br />
Softgels<br />
Lipophilic<br />
matrices<br />
d-alpha<br />
tocopherol<br />
succinate<br />
Covitol®<br />
1185 HPMC EU<br />
Covitol®<br />
1210 EU<br />
Powder<br />
Powder<br />
Tablets<br />
Capsules<br />
Tablets<br />
Capsules<br />
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COVI-OX®<br />
COVI-OX®<br />
Natural mixed tocopherols<br />
Contains<br />
d-alpha, d-beta, d-gamma and d-delta<br />
tocopherol<br />
Source<br />
Vegetable oil distillate<br />
Benefits<br />
Antioxidant<br />
Protects fats and oils against oxidation<br />
Applications authorized in the EC<br />
Use as antioxidant in food products and food<br />
supplements (fats, vegetable and marine<br />
oils, cereals, drinks, dairy products, bars, pet<br />
food)<br />
Food supplements<br />
EC Regulatory status<br />
Approved as food <strong>add</strong>itive (antioxidant)<br />
in Europe (E 306, Tocopherol-rich<br />
extract)<br />
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Forms and applications<br />
Product<br />
Concentration<br />
Form<br />
Application<br />
Covi-ox® T-95 EU<br />
950 mg/g<br />
Oil<br />
Covi-ox® T-90 EU 900 mg/g Oil<br />
Covi-ox® T-70 EU 700 mg/g Oil<br />
Covi-ox® T-50 EU 500 mg/g Oil<br />
Covi-ox® T-30<br />
P EU<br />
300 mg/g Waterdispersible<br />
powder<br />
Fats and oils<br />
Cereals<br />
Drinks<br />
Dairy products<br />
Bars<br />
Pet food<br />
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DELIOS®<br />
DELIOS®<br />
Medium-chain<br />
triglycerides<br />
Contains<br />
Mix of medium-chain<br />
fatty acids (C8 and C10)<br />
Source<br />
Palm kernel and coconut oil<br />
Properties<br />
In nutrition:<br />
Easily digested<br />
Rapid source of energy<br />
Increases satiety<br />
Not stored in adipose tissue<br />
For technological application:<br />
Excellent resistance to oxidation<br />
Low viscosity<br />
Solvent and base for colorants and<br />
flavorings<br />
Anti-sticking<br />
Anti-dusting<br />
Applications authorized in the EC<br />
Functional foods<br />
Sports nutrition<br />
Medical and infant nutrition<br />
Food products: margarines, sauces,<br />
bars, oils, bread-making products,<br />
dairy products, drinks, powder<br />
mixes<br />
EC Regulatory status<br />
Vegetable oil, food ingredient<br />
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Forms and applications<br />
Product<br />
Delios® V<br />
Delios® S<br />
Delios® S Powder<br />
Delios® C<br />
Concentration<br />
60% C8<br />
40% C10<br />
70% C8<br />
30% C10<br />
70%<br />
oil content<br />
> 98% C10<br />
Form<br />
Liquid<br />
Liquid<br />
Powder<br />
Solid<br />
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PLANTALIN TM<br />
PLANTALIN TM<br />
Standardized, water-soluble plant extracts<br />
for food applications<br />
WELL-BEING CONCEPT<br />
PLANTALIN TM Aloe vera<br />
Source<br />
Aloe barbadensis M.<br />
Part used: leaf<br />
Form<br />
Application<br />
Gel or water-dispersible<br />
powder<br />
Drinks, dairy products, bars<br />
PLANTALIN TM Green tea low caffeine<br />
Source<br />
Camellia sinsensis L.<br />
Part used: leaf<br />
Standardization<br />
Form<br />
Application<br />
Caffeine 0.25-0.50% (HPLC)<br />
Total catechins > 20% (HPLC)<br />
Water-dispersible powder<br />
Drinks, dairy products, bars<br />
PLANTALIN TM Rooibos<br />
Source<br />
Aspalathus linearis L.<br />
Parts used: stem and leaf<br />
Standardization<br />
Form<br />
Application<br />
Orientin and Isoorientin > 0.50% (HPLC)<br />
Water-dispersible powder<br />
Drinks, dairy products, bars<br />
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ENERGY AND WELL-BEING<br />
CONCEPTS<br />
PLANTALIN TM Ginseng<br />
Source<br />
Panax Ginseng C.A. Meyer<br />
Part used: root<br />
Standardization<br />
Form<br />
Application<br />
Total ginsenosides > 2%<br />
(HPLC, rg1)<br />
Water-dispersible powder<br />
Drinks, dairy products, bars<br />
ENERGY CONCEPT<br />
PLANTALIN TM Guarana<br />
Source<br />
Paullinia cupana H.B.K.<br />
Part used: seed<br />
Standardization<br />
Form<br />
Application<br />
Caffeine > 5% (HPLC)<br />
Water-dispersible powder<br />
Drinks, dairy products, bars<br />
PLANTALIN TM Green tea<br />
Source<br />
Camellia sinensis L.<br />
Part used: leaf<br />
Standardization<br />
Form<br />
Application<br />
Caffeine 2 – 4.5% (HPLC)<br />
Total catechins > 20% (HPLC)<br />
Water-dispersible powder<br />
Drinks, dairy products, bars<br />
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CALMING AND WELL-BEING<br />
CONCEPTS<br />
PLANTALIN TM Honeybush<br />
Source<br />
Cyclopia ssp.<br />
Parts used: leaf and stem<br />
Standardization<br />
Form<br />
Application<br />
Total mangiferin > 1.5% (HPLC)<br />
Water-dispersible powder<br />
Drinks, dairy products, bars<br />
PLANTALIN TM Lemon balm<br />
Source<br />
Melissa officinalis L.<br />
Part used: leaf<br />
Standardization<br />
Form<br />
Application<br />
Rosmarinic acid > 2% (HPLC)<br />
Water-dispersible powder<br />
Drinks, dairy products, bars<br />
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CALMING CONCEPT<br />
PLANTALIN TM Passion flower<br />
Source<br />
Passiflora incarnata L.<br />
Part used: aerial part<br />
Standardization<br />
Form<br />
Application<br />
Total equivalent flavonoids<br />
Vitexin > 2% (UV/Vis)<br />
Water-dispersible powder<br />
Drinks, dairy products, bars<br />
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CONTACT US<br />
By phone<br />
+49-2173-4995-226<br />
By e-mail<br />
nutrition.health@cognis.com<br />
www.cognis.com<br />
All information given in this statement reflects<br />
our current knowledge and interpretation of<br />
relevant legislation and legal practice. COGNIS<br />
EXPRESSLY DISCLAIMS ANY RESPONSIBILITY FOR<br />
THE SUITABILITY OF THIS INFORMATION FOR<br />
PRODUCTS FOR ANY SPECIFIC OR PARTICULAR<br />
PURPOSES INTENDED BY THE USER.<br />
Our suggestions do not release <strong>Cognis</strong> <br />
customers from evaluating the individual<br />
products as to their legal compliance. <strong>Cognis</strong><br />
does not assume any liability or risk involved in<br />
the use or marketing of its products as<br />
the conditions of use are beyond its<br />
control. The user of the products is<br />
solely responsible for compliance<br />
with all laws and regulations<br />
applying to the use of the<br />
products. Revision 1. Produced in<br />
July 2008.<br />
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www.cognis.com<br />
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