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Human Dignity and Bioethics

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<strong>Human</strong> <strong>Dignity</strong> <strong>and</strong> Respect for Persons | 31<br />

by these events <strong>and</strong> forces were apparent but nascent in American<br />

society. The process of developing <strong>and</strong> exploiting the potential of<br />

biomedicine <strong>and</strong> biotechnology had been well underway for years,<br />

but the effort to reckon with the full (<strong>and</strong> still uncertain) implications<br />

of this potential was in its infancy, as was the field of bioethics<br />

itself. The issues that, by Congressional m<strong>and</strong>ate, dominated the<br />

agenda of the National Commission were ones that could reasonably<br />

comm<strong>and</strong> public support <strong>and</strong> concern: what ethical precepts<br />

should guide clinical research, permitting it to go forward on a more<br />

secure moral footing? And in justifying its response to this question,<br />

in advocating the practical application of the Belmont principles,<br />

the National Commission could appeal to beliefs <strong>and</strong> perceptions<br />

that derive their normative authority from widespread acceptance in<br />

American society <strong>and</strong>—especially in the case of the principle of respect<br />

for persons, with its focus on autonomy—from deep roots in<br />

the American political tradition.<br />

Thirty years later, it would be an understatement to say that much<br />

has changed, although many features of the present era were discernible<br />

in germinal form at the time of the National Commission. The<br />

ideological tensions that led to <strong>and</strong> were further aggravated by Roe v.<br />

Wade have evolved into the stark polarities of today’s so-called culture<br />

wars, thereby frustrating if not precluding any facile appeal to a common,<br />

shared morality. Meanwhile, a steady stream of discoveries in<br />

biomedicine <strong>and</strong> novel applications of biotechnology have extended<br />

<strong>and</strong> strengthened our reach over human biology, equipping us with<br />

new tools, not only for curing <strong>and</strong> ameliorating human disease but<br />

also for enhancing certain traits <strong>and</strong> capacities, for conceiving <strong>and</strong><br />

gestating human life, <strong>and</strong> for forestalling the fate that awaits us all,<br />

death itself. Today, more than ever before, we seem poised for mastery<br />

over many aspects of human life, including those that unite us<br />

with nonhuman animals <strong>and</strong> those that separate us from them. For<br />

some, these achievements of the ongoing revolution in biomedicine<br />

<strong>and</strong> biotechnology testify to the triumph of human ingenuity <strong>and</strong><br />

to the efficacy of the human will to fashion our environment—<strong>and</strong><br />

ourselves—as we wish. For others, the claim that all these impressive<br />

achievements make positive contributions to human flourishing<br />

is misguided <strong>and</strong> even dangerous, neglecting the sober lesson of<br />

Tuskegee: that the quest for new knowledge, <strong>and</strong> for new applications

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