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Why A NanoTite Tapered Implant? - Dental-Depot

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A Reflection Of<br />

The Latest Advancement<br />

In <strong>Implant</strong> Dentistry –<br />

The Bone Bonding ® * <strong>NanoTite</strong> <strong>Tapered</strong> <strong>Implant</strong><br />

Now Available:<br />

<strong>NanoTite</strong> <strong>Tapered</strong><br />

PREVAIL ® <strong>Implant</strong><br />

*The interlocking of the newly formed cement line matrix of bone with the implant surface.


This <strong>Tapered</strong> <strong>Implant</strong><br />

Makes A Strong Impression<br />

Expanding the universe of dental implant innovations is our<br />

mission. With this in mind, BIOMET 3i has combined our<br />

knowledge of implant dentistry and nanotechnology to<br />

launch a new addition to our <strong>NanoTite</strong> <strong>Implant</strong> Family Of<br />

Products.<br />

Designed for optimal performance, the <strong>NanoTite</strong> <strong>Tapered</strong><br />

<strong>Implant</strong> offers:<br />

A True <strong>Tapered</strong> Shape – The<br />

<strong>NanoTite</strong> <strong>Tapered</strong> <strong>Implant</strong><br />

closely approximates the<br />

shape of a natural tooth root.<br />

An Innovative Thread Design –<br />

Thread angle, depth and pitch<br />

produce an anchoring “bite<br />

in bone” response providing<br />

initial stability throughout the<br />

length of the implant, while<br />

maximizing Bone-To-<strong>Implant</strong> Contact (BIC).<br />

A Domed Apical End – Potentially reduces trauma in areas<br />

where implant placement closely approximates vital<br />

structures such as the alveolar nerve or sinus membrane.<br />

Ease Of Insertion With Spiral Incremental<br />

Cutting Edge – Self-tapping with progressive cutting edges<br />

in a helical pattern with trailing thread relief.<br />

Surgical And Restorative Flexibility – The <strong>NanoTite</strong><br />

<strong>Tapered</strong> <strong>Implant</strong> is conveniently color-coded for easy<br />

identification and is available in the Certain ® QuickSeat ®<br />

Internal Connection and external hex configurations.


In An Atmosphere All Its Own<br />

With the new <strong>NanoTite</strong> <strong>Tapered</strong> PREVAIL ® <strong>Implant</strong>,<br />

clinicians get to the root of the issue.<br />

Integrated platform switching with the<br />

<strong>NanoTite</strong> <strong>Tapered</strong> PREVAIL <strong>Implant</strong>.<br />

Certain® QuickSeat®<br />

Internal Connection<br />

Threads Widen Laterally While<br />

Extending To The Apical End<br />

<strong>NanoTite</strong> <strong>Implant</strong> Surface Technology<br />

The Entire Length Of The <strong>Implant</strong><br />

Spiral Incremental<br />

Cutting Edge<br />

Domed Apical End<br />

<strong>Why</strong> A <strong>NanoTite</strong> <strong>Tapered</strong> <strong>Implant</strong>?<br />

The complex architecture at the nano-scale renders the <strong>NanoTite</strong> <strong>Implant</strong><br />

a Bone Bonding ® Surface by the interlocking of the newly formed cement<br />

line matrix of bone with the implant surface.<br />

Preclinical studies indicate that the <strong>NanoTite</strong> <strong>Implant</strong> nanotopography<br />

provides a greater rate and extent of osseointegration as compared<br />

to the OSSEOTITE Surface*. In addition, the true tapered design of this<br />

implant closely approximates a natural tooth root. The combination of<br />

these features provides clinicians with significant treatment options for<br />

cases to include:<br />

• Immediate And Accelerated Loading Protocols<br />

• Immediate Placement In Extraction Sockets<br />

• Sites With Convergent Roots Of Adjacent Teeth<br />

• Cases With Ridge Concavities<br />

• Simultaneous Grafted Sites And <strong>Implant</strong> Placement<br />

• <strong>Implant</strong> Placement With Sinus Lift Procedures<br />

• Aesthetic Areas Where Bone Preservation Is Critical<br />

• Locations Requiring Short Or Wide <strong>Implant</strong>s<br />

• Soft Bone (Type IV)<br />

A study began in February of 2006 to<br />

evaluate the preparation and placement<br />

of BIOMET 3i’s enhanced <strong>Tapered</strong><br />

OSSEOTITE ® <strong>Implant</strong>s. Twelve centers<br />

reported results on 133 patients and 208<br />

implants (123 tapered implants, 85 nontapered<br />

control implants) with four reported<br />

failures to date. This evaluation has led to the<br />

development of the new <strong>NanoTite</strong> <strong>Tapered</strong><br />

<strong>Implant</strong>s now available from BIOMET 3i.*<br />

*Data on file.


A Bone Bonding ® * Surface That’s Out Of This World<br />

The <strong>NanoTite</strong> <strong>Implant</strong> builds on the success of the OSSEOTITE ® Surface by creating a more complex surface topography<br />

and maximizing the potential biological benefits of Calcium Phosphate (CaP).<br />

For more than 10 years and with documentation from numerous global multicenter clinical evaluations, the OSSEOTITE<br />

Surface has proven to be one of the most predictable and well-researched surfaces 1-8 . Clinical studies on the<br />

OSSEOTITE Surface continue to document the benefits of increased Contact Osteogenesis, especially in poor-quality bone.<br />

OSSEOTITE Surface at 20,000x magnification<br />

<strong>NanoTite</strong> Surface at 20,000x magnification<br />

Through a solution-based form of particle self-assembly called the Discrete Crystalline Deposition (DCD ) Process,<br />

individual deposits of discrete crystals of CaP are deposited onto the implant surface and occupy approximately 50%<br />

of the OSSEOTITE Substrate Surface 9 . In so doing, the DCD Process also increases the micro-surface area by 200% 10 ,<br />

providing greater micro-complexity for new bone attachment and formation.<br />

The DCD Process<br />

1. Nanometer-scale, ultra small particles of highly crystalline<br />

Calcium Phosphate (CaP) are suspended in the solution<br />

2. These particles are then prompted to “Self-Assemble”<br />

onto the implant titanium oxide surface<br />

3. This results in discrete crystal deposits of 20-100 Nanometers<br />

in length on the dual acid etched OSSEOTITE <strong>Implant</strong> Surface.<br />

The shear strength of crystal attachment to the OSSEOTITE<br />

Surface exceeds the minimum shear strength value of 34.5<br />

MPa, set by the ASTM standard (F 1609-03) for attachment<br />

of traditional HA coatings to implant surfaces<br />

1<br />

2<br />

3<br />

*The interlocking of the newly formed cement line matrix of bone with the implant surface.


<strong>Why</strong> is there a need for a tapered implant featuring a more complex surface topography?<br />

“When I have to treat difficult cases, most of the time I use BIOMET 3i’s<br />

<strong>Tapered</strong> <strong>Implant</strong> due to its design to achieve primary stability. This is very<br />

important because the development and the mastery of modern implant<br />

surgery are based on very good implant fixation. For example, in an<br />

immediate implant placement after an extraction, the BIOMET 3i <strong>Tapered</strong><br />

<strong>Implant</strong> can achieve initial stability even with a limited amount of initial<br />

bone; another very good indication is the presence of a thin ridge. For me,<br />

the BIOMET 3i <strong>Tapered</strong> <strong>Implant</strong> contributes to reducing my stress in any kind<br />

of implant surgery.”<br />

“BIOMET 3i’s <strong>Tapered</strong> <strong>Implant</strong> is the most widely used implant in my<br />

practice. Because of its versatility, it is suitable for cases involving poor<br />

quality bone (e.g., Type III and IV). I also use it to increase the level of<br />

primary stability in regenerative procedures with advanced surgical<br />

techniques and with sites that present specific anatomical configurations.”<br />

Dr. Leonello Biscaro<br />

Active Member Of The Italian Society Of Prosthodontics<br />

Dr. Frederic Chiche<br />

Former President Of The French Society Of Esthetic Dentistry<br />

A New Phase Changing The Atmosphere Of Success<br />

A comprehensive series of animal<br />

studies was performed on the<br />

<strong>NanoTite</strong> <strong>Implant</strong>. One animal model<br />

demonstrated 160% increase in BIC 11<br />

versus the OSSEOTITE ® <strong>Implant</strong>.<br />

Additionally, the microtopography<br />

of the OSSEOTITE Surface, combined<br />

with the DCD Process renders the<br />

<strong>NanoTite</strong> <strong>Implant</strong> a Bone-Bonding ®<br />

Surface.<br />

Preclinical Studies<br />

Human histology studies have<br />

also demonstrated an impressive<br />

amount of BIC around the <strong>NanoTite</strong><br />

<strong>Implant</strong> Surface.<br />

Ongoing Preclinical And Clinical Studies<br />

Bone-To-<strong>Implant</strong> Contact Outcome<br />

At Eight Weeks Of Healing<br />

Int J Periodontics Restorative Dent<br />

2007;27:211-219<br />

“Certainly these results are incredible. I don’t think it’s because we’ve discovered a new<br />

phenomenon in biology, but certainly the interface which has been created between bone<br />

and this particular implant surface is quite different from anything ever seen before.”<br />

John E. Davies, BDS, PhD, DSc, FSBE<br />

Toronto, Canada


Site Preparation That Is In A World By Itself<br />

BIOMET 3i’s <strong>NanoTite</strong> <strong>Tapered</strong> <strong>Implant</strong> Surgical Instrumentation provides options that facilitate effective treatment<br />

planning and a successful patient outcome.<br />

Complete Color-Coding For An Intuitive Protocol<br />

Every element of the <strong>NanoTite</strong> <strong>Tapered</strong> <strong>Implant</strong> System — surgical tray, Quad-Shaping Drills (QSDs), Depth/Direction<br />

Indicators (NTDIs), bone taps and implants — is color-coded for easy identification. In addition, the packaging<br />

has been carefully designed to facilitate optimal delivery efficiency.<br />

Precision QSD Shaping Drills And NTDIs<br />

• Designed to match each implant’s diameter and<br />

length for proper preparation, confirmation and<br />

implant placement<br />

• Stepped drill design allows for better visibility of crestal<br />

and subcrestal reference<br />

• Four thin-cutting flutes facilitate cutting stability<br />

and decrease friction<br />

• Pointed end tip allows for vertical downward cutting<br />

“The <strong>NanoTite</strong> <strong>Tapered</strong> <strong>Implant</strong> is designed to achieve<br />

primary stability in all bone qualities, including soft bone.<br />

The implant requires more insertion torque to properly<br />

seat within the osteotomy site. Therefore, it is mandatory<br />

to use the hand ratchet to take full advantage of the<br />

unique design features of this implant.”<br />

Alan Meltzer, DMD<br />

Voorhees, New Jersey<br />

• Corresponding Depth/Direction Indicators (NTDIs) ensure<br />

appropriate depth and angle for every osteotomy performed<br />

Quad Shaping<br />

Drill (QSD)<br />

Depth/Direction<br />

Indicator (NTDI)<br />

Quad Shaping Drill Surgical Kit


Put Order In Your Universe<br />

Optimal Site Preparation, Confirmation And Fit<br />

The specifications of the <strong>NanoTite</strong> <strong>Tapered</strong> <strong>Implant</strong> and<br />

the corresponding QSDs and NTDIs are held to rigorous<br />

tolerances to provide a more closely integrated implantto-osteotomy<br />

fit.<br />

New Full Length Dense Bone Taps<br />

When placing the <strong>NanoTite</strong> <strong>Tapered</strong> <strong>Implant</strong>, the need to<br />

tap the osteotomy may arise, especially in dense bone.<br />

BIOMET 3i has developed a new Dense Bone Tap Kit. This<br />

kit has a specific tap that matches each <strong>NanoTite</strong> <strong>Tapered</strong><br />

<strong>Implant</strong> for optimal site preparation.<br />

What is the significance of improved<br />

surgical instrumentation?<br />

Quad Shaping Drills are designed to improve the<br />

precision of the osteotomy. Depth indicators allow me<br />

to simulate the ultimate position of the implant in the<br />

prepared osteotomy. The combined use of these<br />

instruments is designed to minimize placement<br />

sensitivity of the implant.<br />

Karl Heggland, DDS<br />

Frisco, Colorado<br />

<strong>Tapered</strong> <strong>Implant</strong> Dense Bone Tap Kit<br />

Dense Bone Taps<br />

References<br />

1. Sullivan DY, Sherwood RL, Porter SS. Long-Term Performance of OSSEOTITE ® <strong>Implant</strong>s:<br />

A 6-Year Clinical Follow-Up. Compendium. April 2001;Vol. 22, No. 4.<br />

2. Davarpanah M, Martinez H, Etienne D, Zabalegui I, Mattout P, Chiche F, Michel J. A<br />

Prospective Multicenter Evaluation of 1,538 3i <strong>Implant</strong>s: 1 to 5-year Data.<br />

The International Journal of Oral & Maxillofacial <strong>Implant</strong>s. 2002; Vol. 17, No. 6.<br />

3. Feldman S, Boitel N, Weng D, Kohles SS, Stach RM. Five-Year Survival Distributions<br />

of Short-Length (10mm or less) Machined-Surfaced and OSSEOTITE <strong>Implant</strong>s.<br />

Clinical <strong>Implant</strong> Dentistry and Related Research. 2004; Vol. 6, No. 1.<br />

4. Sullivan D, Vincenzi G, Feldman S. Early Loading of OSSEOTITE <strong>Implant</strong>s 2 Months After<br />

Placement in the Maxilla and Mandible: A 5-year Report. The International Journal<br />

of Oral & Maxillofacial <strong>Implant</strong>s. 2006; Vol. 20, No. 6<br />

5. Stach RM, Kohles SS. A Meta-Analysis Examining the Clinical Survivability of<br />

Machined-Surfaced and OSSEOTITE <strong>Implant</strong>s in Poor-Quality Bone.<br />

<strong>Implant</strong> Dentistry. 2003; Vol. 12, No.1.<br />

6. Testori T, Wiseman L, Woolfe S, Porter SS. A Prospective Multicenter Clinical Study<br />

of the OSSEOTITE <strong>Implant</strong>: Four-Year Interim Report. The International Journal of<br />

Oral & Maxillofacial <strong>Implant</strong>s. 2001;16:193-200.<br />

7. Gaucher H, Bentley K, Roy S, Head T, Blomfield J, Blondeau F, Nicholson L, Chehade A,<br />

Tardif N, Emery R. A Multi-Centre Study of OSSEOTITE <strong>Implant</strong>s Supporting Mandibular<br />

Restorations: A 3-Year Report. Journal of the Canadian <strong>Dental</strong> Association.<br />

October 2001; Vol. 67, No. 9<br />

8. Testori T, Fabbro MD, Feldman S, Vincenzi G, Sullivan D, Rossi R, Anitua E, Bianchi F,<br />

Francetti L, Weinstein RL. A multicenter prospective evaluation of 2-months loaded<br />

OSSEOTITE <strong>Implant</strong>s placed in the posterior jaws: 3-year follow-up results.<br />

Clin. Oral Impl. Res. 2002;13:154-161.<br />

9. Data on file.<br />

10. Suttin Z, Gubbi P. Surface area increase due to discrete-crystalline-deposition of<br />

nanometer-scale CaP crystals. European Association for Osseointegration.<br />

15th Annual Scientific Meeting. October 5-7, 2006. Zurich, Switzerland.<br />

11. Mendes VC, Davies JE. Discrete calcium phosphate nanocrystals enhance<br />

osteoconduction on titanium-based implant surfaces. Canadian Biomaterials Society. 25th<br />

Annual Meeting. May 26-28, 2006. Calgary, Alberta, Canada.<br />

12. Nishimura I, Huang Y, et al. Discrete Deposition of Hydroxyapatite Nano-particles on a<br />

Titanium <strong>Implant</strong> With Predisposing Substrate Microtopography Accelerated Osseointegration.<br />

Nanotechnology. 2007;18:245101(9pp). doi:10.1088/0957-4484/18/24/245101.<br />

13. Mendes VC, Davies JE. Discrete calcium phosphate nanocrystals render titanium<br />

surfaces bone bonding. Int J Oral Maxillofac <strong>Implant</strong>.2007;22:484.


<strong>NanoTite</strong> <strong>Tapered</strong> <strong>Implant</strong><br />

Ordering Information<br />

<strong>NanoTite</strong> <strong>Tapered</strong><br />

Length 3.25mm(D) 4mm(D) 5mm(D) 6mm(D)<br />

8.5mm NINT3285 NINT485 NINT585 NINT685<br />

10.0mm NINT3210 NINT410 NINT510 NINT610<br />

11.5mm NINT3211 NINT411 NINT511 NINT611<br />

13.0mm NINT3213 NINT413 NINT513 NINT613<br />

15.0mm NINT3215 NINT415 NINT515 NINT615<br />

Length 3.25mm(D) 4mm(D) 5mm(D) 6mm(D)<br />

8.5mm<br />

10.0mm<br />

11.5mm<br />

13.0mm<br />

15.0mm<br />

NNT3285 NNT485 NNT585 NNT685<br />

NNT3210 NNT410 NNT510 NNT610<br />

NNT3211 NNT411 NNT511 NNT611<br />

NNT3213 NNT413 NNT513 NNT613<br />

NNT3215 NNT415 NNT515 NNT615<br />

<strong>Tapered</strong> <strong>Implant</strong> Depth/Direction Indicator Kit NTDIK<br />

<strong>NanoTite</strong> <strong>Tapered</strong> Certain PREVAIL ®<br />

Length 4/3mm(P) 5/4mm(P) 6/5mm(P)<br />

8.5mm NIITP4385 NIITP5485 NIITP6585<br />

10.0mm NIITP4310 NIITP5410 NIITP6510<br />

11.5mm NIITP4311 NIITP5411 NIITP6511<br />

13.0mm NIITP4313 NIITP5413 NIITP6513<br />

15.0mm NIITP4315 NIITP5415 NIITP6515<br />

<strong>NanoTite</strong> <strong>Tapered</strong> Certain ®<br />

Quad Shaping Drill Kits (QSD)<br />

Certain Quad Shaping Drill Surgical Kit For <strong>Tapered</strong> <strong>Implant</strong><br />

<strong>Tapered</strong> <strong>Implant</strong> Quad Shaping Drill Premium Upgrade Kit<br />

Quad Shaping Drill Surgical Tray<br />

Depth/Direction Indicator Kit (NTDI)<br />

QNTSK40<br />

QNTSK40U<br />

QNTSKT<br />

Enter A New World In <strong>Dental</strong> <strong>Implant</strong><br />

Technology By Calling Your BIOMET 3i<br />

Sales Representative Today<br />

Dense Bone Tap Kit (NTAPK)<br />

<strong>Tapered</strong> <strong>Implant</strong> Dense Bone Tap Kit<br />

NTAPK<br />

Global Headquarters<br />

4555 Riverside Drive<br />

Palm Beach Gardens, FL 33410<br />

1-800-342-5454<br />

Outside The U.S.: +1-561-776-6700<br />

Fax: +1-561-776-1272<br />

www.biomet3i.com<br />

Sign Up For BIOMET 3i’s Electronic Newsletter “BIOMET 3innovations.” Simply Go Online To www.biomet3i.com/signup<br />

Europe, Middle East & Africa Headquarters<br />

WTC Almeda Park, Ed. 1, Planta 1ª<br />

Pl. de la Pau, s/n<br />

08940, Cornellà de Llobregat<br />

(Barcelona) Spain<br />

Phone: +34-93-470-55-00<br />

Fax: +34-93-371-78-49<br />

Bone Bonding, Certain, OSSEOTITE, PREVAIL and<br />

QuickSeat are registered trademarks and DCD,<br />

<strong>NanoTite</strong> and Platform Switching are trademarks<br />

of BIOMET 3i LLC. BIOMET is a registered<br />

trademark and BIOMET 3i and design are<br />

trademarks of BIOMET, Inc.<br />

©2008 BIOMET 3i LLC. All rights reserved.<br />

ART1007EU<br />

Rev B 07/08<br />

SUBSIDIARIES<br />

DISTRIBUTORS<br />

AUSTRALIA<br />

Phone: +61-2-9855-4444<br />

Fax: +61-2-9888-9900<br />

AUSTRIA<br />

Phone: +43-(0)6235-200-45<br />

Fax: +43-(0)6235-200-45-9<br />

BELGIUM<br />

Phone: +32-2-5410290<br />

Fax: +32-2-5410291<br />

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Phone: +55-11-5081-4405<br />

Fax: +55-11-5081-7484<br />

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Phone: +514-956-9843<br />

Fax: +514-956-9844<br />

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Phone: +33-1-41054343<br />

Fax: +33-1-41054340<br />

GERMANY<br />

Phone: +49-721-255177-10<br />

Fax: +49-721-255177-73<br />

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Phone: +353-1-800-552-752<br />

Fax: +44-1628-820182<br />

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Phone: +52-55-5679-1619<br />

Fax: +52-55-5684-8098<br />

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Phone: +31-78-629-2800<br />

Fax: +31-78-629-2801<br />

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Phone: +64-508-122-221<br />

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Phone: +46-40-17-6090<br />

Fax: +46-40-17-6099<br />

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Phone: +351-21-000-1647<br />

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Phone: +34-93-470-59-50<br />

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Phone: +41-44-200-76-00<br />

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Phone: +90-212-573-6916<br />

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U.K.<br />

Phone: +44-800-652-1233<br />

Fax: +44-1628-820182<br />

ARGENTINA<br />

<strong>Dental</strong>max, SA<br />

Phone: +541-1482-71001<br />

Fax: +541-1482-67373<br />

CHILE<br />

Cybel, SA<br />

Phone: +56-2-2321883<br />

Fax: +56-2-2330176<br />

CHINA<br />

Atek Inc.<br />

Phone: +86-21-6329-1265<br />

Fax: +86-21-6329-1620<br />

COLOMBIA<br />

3i Colombia<br />

Phone: +571-612-9362<br />

Fax: +571-620-6412<br />

COSTA RICA<br />

<strong>Implant</strong>ec S.A.<br />

Phone: +506-234-9043<br />

Fax: +506-224-7620<br />

EL SALVADOR<br />

Dentimerc SA de CV<br />

Phone: +503-263-6350<br />

Fax: +503-263-6676<br />

GREECE<br />

Impladend <strong>Dental</strong> <strong>Implant</strong>s LLC<br />

Phone: +30-2310-501-651<br />

Fax: +30-2310-522-417<br />

ISRAEL<br />

H.A. Systems<br />

Phone: +972-3-6138777<br />

Fax: +972-3-6138778<br />

HONG KONG<br />

Ositek Inc., Ltd.<br />

Phone: +852-8121-6601<br />

Fax: +852-3747-3754<br />

ITALY<br />

Biomax, srl.<br />

Phone: +39-0444-913410<br />

Fax: +39-0444-913695<br />

JAPAN<br />

<strong>Implant</strong> Innovations Japan<br />

Phone: +81-66-868-3012<br />

Fax: +81-66-868-2444<br />

KOREA<br />

Jungsan 3i Corp.<br />

Phone: +82-2-516-1808<br />

Fax: +82-2-514-9434<br />

MIDDLE EAST<br />

3i MENA s.a.l.<br />

Middle East And North Africa<br />

Phone: +961-1-694000<br />

Fax: +961-1-694222<br />

PARAGUAY<br />

Andres H. Arce y Cia SRL<br />

Phone: +595-21-208185<br />

Fax: +595-21-496291<br />

POLAND<br />

<strong>Dental</strong> <strong>Depot</strong><br />

Phone: +48-71-341-3091<br />

Fax: +48-71-343-6560<br />

RUSSIA<br />

Com-<strong>Dental</strong><br />

Phone: +7-495-797-6686<br />

Fax: +7-499-242-9567<br />

SINGAPORE<br />

Asia <strong>Implant</strong> Support & Services<br />

Phone: +65-6223-2229<br />

Fax: +65-6220-3538<br />

SOUTH AFRICA<br />

Selective Surgical CC<br />

Phone: +27-11-991-7007<br />

Fax: +27-11-672-1391<br />

TAIWAN<br />

Kuo Hwa <strong>Dental</strong> Suppliers Co., Ltd.<br />

Phone: +886-2-2226-1770<br />

Fax: +886-2-2226-8747<br />

THAILAND<br />

3i (Thailand) Co., Ltd.<br />

Phone: +662-252-6685<br />

Fax: +662-252-6686<br />

UKRAINE<br />

Com-<strong>Dental</strong><br />

Phone: +38-067-7007667<br />

Fax: +38-044 5017117<br />

URUGUAY<br />

Pro3implant S.R.L.<br />

Phone: +598-2-4034163<br />

Fax: +598-2-4034163

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