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NNU: Flucloxacillin + Gentamicin Benzylpenicillin + Gentamicin ...

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Paediatric Empirical<br />

Antimicrobial Card<br />

Expires: August 2012<br />

SEPSIS<br />

CNS<br />

RESPIRATORY<br />

Condition<br />

Early (48 hours) neonatal sepsis<br />

Other: Amoxicillin + Cefotaxime<br />

Infant/child sepsis<br />

Cefotaxime<br />

If toxin production suspected add Clindamycin IV<br />

Immune compromise sepsis Tazocin + stat <strong>Gentamicin</strong><br />

Neonatal/infant 5years<br />

Royal Devon and Exeter<br />

NHS Foundation Trust<br />

Oral Amoxicillin<br />

IV Co-amoxiclav if severe/not tolerating oral<br />

Oral Azithromycin<br />

[+ Amoxicillin if Strep pneumo suspected] or<br />

IV Co-amoxiclav + PO Azithromycin if severe


Paediatric Empirical<br />

Antimicrobial Card<br />

Expires: August 2012<br />

Condition<br />

First-line regimen<br />

Royal Devon and Exeter<br />

NHS Foundation Trust<br />

GU<br />

ENT<br />

BONE/JOINT/<br />

SOFT TISSUE<br />

Infant 3 months: Pyelonephritis<br />

(i.e. fever or loin pain)<br />

>3 months: Cystitis<br />

Uncomplicated otitis media<br />

Bacterial tonsilitis with exudate<br />

Suspected bacterial lymphadenitis<br />

Peri-orbital (preseptal) cellulitis<br />

Orbital cellulitis<br />

Acute soft tissue infection<br />

Acute bone/joint infection<br />

IV Amoxicillin + <strong>Gentamicin</strong><br />

Oral Co-amoxiclav<br />

If vomiting or no response to orals after 24 hours<br />

IV Amoxicillin + <strong>Gentamicin</strong><br />

Oral Trimethoprim<br />

Symptomatic measures<br />

Consider oral Amoxicillin in infants<br />

Oral Penicillin V<br />

IV Co-amoxiclav<br />

Antibiotics not required for viral infections<br />

IV Co-amoxiclav<br />

IV Clindamycin + Cefotaxime<br />

Oral <strong>Flucloxacillin</strong><br />

If necrotising infection or toxin production suspected<br />

IV flucloxacillin + IV clindamycin<br />

Amoxicillin + <strong>Flucloxacillin</strong>

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