10 A niversary of IIMCB

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A scheme of initial steps during µ opioid receptor (GPCR family) activation by the agonist morphine (shown as a structural formula). The arrows indicate motion of a ligand (wider arrow) and breaking of a connection (narrow arrow) between transmembrane helices TM3 (green) and TM7 (red) which constitutes the “3-7 lock” molecular switch (author: Sławomir Filipek).
Laboratory of Biomodelling Lab Leader: Sławomir Filipek, PhD, DSc. Habil. Junior Researchers: Michał Koliński, MSc Aleksander Dębiński, MSc Wojciech Puławski, MSc Undergraduate student: Krzysztof Młynarczyk Left the Laboratory in 2008: Krzysztof Jóźwiak – Post-doctoral Fellow Krystiana Krzyśko – PhD defense, April 2008 Anna Zwolińska – MSc defense, Sep. 2008
Page 1 and 2: INTERNATIONAL INSTITUTE OF MOLECULA
Page 3 and 4: Contents International Institute of
Page 5 and 6: laboratories were launched: the Lab
Page 7 and 8: International Advisory Board Struct
Page 9 and 10: International Advisory Board of the
Page 11 and 12: Description of the Institute’s Ac
Page 13 and 14: Grants 7 th Framework Programme •
Page 15 and 16: ioinformatics to characterize and d
Page 17 and 18: Scientific Meetings and Lectures
Page 19 and 20: Lab Leaders Competitions The princi
Page 21 and 22: Diversity of Funding IIMCB’2008 A
Page 23 and 24: Department of Molecular Biology Lab
Page 25 and 26: Selected publications • Wawrzynow
Page 27 and 28: Fig. 3. Massive overexpression of H
Page 29 and 30: Laboratory of Bioinformatics and Pr
Page 31 and 32: Publications in 2008 • Orlowski J
Page 33 and 34: cross-linking, mass spectrometry, c
Page 35 and 36: Laboratory of Structural Biology MP
Page 37 and 38: • Filipek R, Potempa J, Bochtler
Page 39 and 40: Fig. 4. Overview of peptidoglycan a
Page 41 and 42: Laboratory of Neurodegeneration Lab
Page 43 and 44: Publications in 2008 • Bojarski L
Page 45 and 46: Fig. 2. 21 days in vitro hippocampa
Page 47: involved in defence against pathoge
Page 51 and 52: • Jozwiak K, Krzysko KA, Bojarski
Page 53 and 54: Fig. 3. Superimposition of EF-hand
Page 55 and 56: Laboratory of Cell Biology Lab Lead
Page 57 and 58: Description of Current Research The
Page 59 and 60: Fig. 2. Endocytosis of transferrin
Page 61 and 62: Laboratory of Molecular and Cellula
Page 63 and 64: • Swiech L, Perycz M, Malik A, Ja
Page 65 and 66: target of rapamycin). mTOR is a ser
Page 67 and 68: Fig. 3: mTOR inhibition impairs mic
Page 69 and 70: Laboratory of Cell Cortex Mechanics
Page 71 and 72: Research The main goal of the group
Page 73 and 74: Fig. 3: Oscillations induced by las
Page 75 and 76: Laboratory of Protein Structure Lab
Page 77 and 78: 1. Integrase superfamily Integrase
Page 79 and 80: Centre for Innovative Bioscience Ed
Page 81 and 82: The Polish Volvox web site (http://
Page 83 and 84: Laboratory of Protein Structure Mar
Page 85 and 86: Centre for Innovative Bioscience Ed
Page 87: International Institute of Molecula

10 A niversary of IIMCB

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