10 A niversary of IIMCB
10 A niversary of IIMCB
10 A niversary of IIMCB
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A scheme <strong>of</strong> initial steps during µ opioid receptor (GPCR family) activation by the agonist morphine (shown as a<br />
structural formula). The arrows indicate motion <strong>of</strong> a ligand (wider arrow) and breaking <strong>of</strong> a connection (narrow<br />
arrow) between transmembrane helices TM3 (green) and TM7 (red) which constitutes the “3-7 lock” molecular switch<br />
(author: Sławomir Filipek).
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