FOBT METODOU OC-SENSOR - Dialab

FOBT METODOU OC-SENSOR - Dialab FOBT METODOU OC-SENSOR - Dialab

15.11.2012 Views

LABORATORNÍ DIAGNOSTIKA V GASTROENTEROLOGII Kocna P. 16 1200 1000 800 600 400 200 0 STABILITA KONCENTRACE Hb Vzorky retestovány retestov retestovány ány 5x během 10-14 10 10-14 14 dnů, uchovány při pokojové teplotě ng/ml ng ng/ml /ml Kolorektální karcinom Adenomy pokročilé Adenomy drobné 0 2-3 4-6 6-9 8-12 10-14 dny Leo G.M. van Rossum1, Rossum1 Rossum1, Anne F. van Rijn, Rijn Rijn, Martijn G.H. van Oijen et others: others others: False negative fecal occult blood tests due to delayed sample return in colorectal cancer screening, screening screening, , Int. Int Int. . J. Cancer 2009

LABORATORNÍ DIAGNOSTIKA V GASTROENTEROLOGII Kocna P. 17 OPTIMALIZACE CUT-OFF CUT CUT-OFF OFF HODNOTY Studie VFN a 1.LFUK 1. LFUK Praha a IKEM Praha 2008 - 2009 813 nemocných nemocných indikovaných ke kolonoskopii optimalizace cut-off cut off hodnoty v rozsahu 50 - 150 ng/ml ng/ml optimální cut-off cut off je 75 ng/ml ng/ml detekce KRCA: KRCA senzitivita 90%, specificita 89%, přesnost 89% Kovarova JT, JT JT, Kocna P, Kohout P, Vranova J, Vanickova Z, Granatova J, Zak A, Lukas K, Celko MA. MA MA. Quantitative Immunochemical Fecal Occult Blood Test in Colorectal Carcinoma Screening in the Czech Republic. Republic Republic. . Prague - 2009 200 2009 9 Optimal cut-off cut cut-off off value 76 ng/ml ng ng/ml /ml Cut-off Cut Cut-off off value determines screening performace of a quantitative immunochemical FOBT van Rossum LGN, LGN LGN, , van Rijn AF, AF AF, Laheij RJF, RJF RJF, , van Oijen MGH.... MGH MGH.... .... Vienna 2008

LABORATORNÍ DIAGNOSTIKA V GASTROENTEROLOGII Kocna P.<br />

16<br />

1200<br />

1000<br />

800<br />

600<br />

400<br />

200<br />

0<br />

STABILITA KONCENTRACE Hb<br />

Vzorky retestovány<br />

retestov retestovány ány 5x během 10-14 10 10-14 14 dnů, uchovány při pokojové teplotě<br />

ng/ml ng ng/ml /ml<br />

Kolorektální karcinom<br />

Adenomy pokročilé<br />

Adenomy drobné<br />

0 2-3 4-6 6-9 8-12 10-14<br />

dny<br />

Leo G.M. van Rossum1, Rossum1 Rossum1, Anne F. van Rijn, Rijn Rijn, Martijn G.H. van Oijen et others: others others:<br />

False negative fecal occult blood tests due to delayed sample return<br />

in colorectal cancer screening, screening screening, , Int. Int Int. . J. Cancer 2009

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