QSAR in Development of Antidepressants
QSAR in Development of Antidepressants
QSAR in Development of Antidepressants
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Future drugs<br />
• SSRI current drug <strong>of</strong> choice<br />
– less side effects and toxicity than1 st<br />
generation<br />
– Toxicity<br />
– almost equal efficacy<br />
• Ideal drug<br />
– Faster effect, specificity, fewer side effects<br />
• 5-HT 1A antagonist augmented with SSRI<br />
show biological effect <strong>in</strong> one week
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