QSAR in Development of Antidepressants
QSAR in Development of Antidepressants QSAR in Development of Antidepressants
from chem.memphis.edu
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01.04.2015
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Synthetic scheme S OH N S OH N O O C 2 H 5 H S OH N O NHCH 3 duloxetine S
Synthetic scheme
- Page 1 and 2: The Next Generation of Antidepressa
- Page 3 and 4: Depression as a Disease • 1 out 5
- Page 5 and 6: Serotonin Hypothesis • serotonerg
- Page 7 and 8: Serotonin effect Phil Skolnick, P.
- Page 9 and 10: Project Aim • explore a faster ac
- Page 11 and 12: QSAR Design • Create training set
- Page 13 and 14: Why use GFA • builds multiple mod
- Page 15 and 16: • r 2 =.87 QSAR results • valid
- Page 17 and 18: Strategy Nh 2 fluoxetine F Cl O H N
- Page 19: Synthetic scheme S antidepressants
- Page 23: References • Phil Skolnick, P. P.
Synthetic scheme
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