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Spring 2010 - Karmanos Cancer Institute

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HOPE<strong>Spring</strong> <strong>2010</strong><br />

A P U B L I C A T I O N O F T H E B A R B A R A A N N K A R M A N O S C A N C E R I N S T I T U T E<br />

INSIDE:<br />

FIGHTING<br />

CANCER<br />

WITHOUT FEAR<br />

Top-notch<br />

cancer care<br />

LOCAL<br />

METEOROLOGIST<br />

OVERCOMES<br />

CANCER<br />

Early detection<br />

is key<br />

ADVANCING<br />

CANCER SCIENCE<br />

Partners invest in<br />

scientific research


PRESIDENT’S LETTER<br />

Dear Friends,<br />

I am extremely honored to serve as the president and chief executive officer<br />

of the Barbara Ann <strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong>.<br />

Since joining <strong>Karmanos</strong> Feb. 1, I have personally seen how the institution<br />

lives up to its reputation for world-class cancer care and cutting-edge<br />

scientific research. Oncologists and other medical professionals have long<br />

been aware of scientific advancements made here, such as the development<br />

of new cancer-fighting drugs that have gone on to receive FDA approval<br />

by the U.S. government. This translates into having advanced treatment<br />

options and therapies for our patients.<br />

I came to <strong>Karmanos</strong> because I want to lead and be associated with an<br />

institution that will make a significant impact on cancer. Judging from<br />

what I’ve seen so far, I know I am in the right place.<br />

Gerold Bepler, M.D., Ph.D<br />

President & Chief Executive Officer<br />

John C. Ruckdeschel, M.D.<br />

ON THE COVER<br />

PRESIDENT AND CHIEF EXECUTIVE OFFICER When David Lepper was diagnosed with an<br />

BARBARA ANN KARMANOS CANCER INSTITUTE aggressive cancer that affects the head and<br />

neck area, he knew he wanted to be treated<br />

at the <strong>Karmanos</strong> <strong>Cancer</strong> Center. Following<br />

surgery, radiation and chemotherapy, he has<br />

been cancer-free for six years.<br />

(Read more on pages 4–5)<br />

Cover image by Stephen Lengnick, Plum Street Studio<br />

...................................................<br />

SPRING <strong>2010</strong><br />

VOLUME 6 | NUMBER 1<br />

...................................................<br />

ABOUT <strong>Karmanos</strong><br />

The Barbara Ann <strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong><br />

is one of only 40 National <strong>Cancer</strong><br />

<strong>Institute</strong>-designated comprehensive cancer<br />

centers in the United States. Federal designation<br />

as a comprehensive cancer center is the<br />

pinnacle of translational oncology research.<br />

...................................................<br />

EXECUTIVE STAFF<br />

Gerold bepler, m.d., Ph.D.<br />

President and Chief Executive Officer<br />

Ann G. Schwartz, Ph.D., MPH<br />

Executive Vice President/Deputy Director<br />

George Yoo, m.d., facs<br />

Chief Medical Officer<br />

GARY MORRISON<br />

Chief Operating Officer<br />

Cynthia K. Sikina<br />

Senior Vice President/Chief Financial Officer<br />

Nick <strong>Karmanos</strong><br />

Vice President, Development<br />

...................................................<br />

<strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong><br />

Board of Directors<br />

Alan S. Schwartz, Chair<br />

Randolph J. Agley, Vice Chair<br />

Charles E. Becker, Lead Vice Chair<br />

Richard M. Gabrys, Vice Chair<br />

W. James Prowse, Vice Chair<br />

Jonathan S. Aaron<br />

Eugene Applebaum<br />

Gerold Bepler, M.D., Ph.D. (ex officio)<br />

Paul Borman<br />

Armando R. Cavazos<br />

Stephen D’Arcy (ex officio)<br />

Debbie Dingell<br />

Joseph Dresner<br />

David W. Drews<br />

Michael E. Duggan<br />

Lillian Erdeljan<br />

Michael Ferrantino, Jr.<br />

Nathan Forbes<br />

Stanley Frankel<br />

Myron Frasier<br />

Bruce A. Gershenson<br />

Adnan Hammad, Ph.D.<br />

Patricia Hartmann<br />

David Jacob<br />

Charles E. Becker, Chair<br />

Timothy Monahan, Vice Chair<br />

Gerold Bepler, M.D., Ph.D. (ex officio)<br />

Leslie C. Bowman<br />

Armando R. Cavazos<br />

Kenneth Eisenberg<br />

Myron Frasier<br />

Thomas A. Goss<br />

S. Scott Hunter<br />

Denise Ilitch<br />

(as of 4/15/10)<br />

Eleanor M. Josaitis<br />

Peter <strong>Karmanos</strong>, Jr.<br />

C. Michael Kojaian<br />

Edward C. Levy, Jr.<br />

Mary Matuja<br />

Timothy Monahan<br />

Paul L. Nine<br />

Jay Noren, M.D., MPH (ex officio)<br />

Thomas D. Ogden<br />

Fred D. Olson<br />

Valerie M. Parisi, M.D. (ex officio)<br />

Hilary Ratner, Ph.D.<br />

Eunice Ring<br />

Richard F. Roth<br />

Gary Sakwa<br />

Nazli G. Sater<br />

Marc R. Schechter<br />

Nettie H. Seabrooks<br />

Nedda N. Shayota<br />

Robert A. Stone<br />

David Trott<br />

Vainutis K. Vaitkevicius, M.D.<br />

Nancy Yaw<br />

<strong>Karmanos</strong> <strong>Cancer</strong> Center<br />

Board of Directors<br />

Valerie M. Parisi, M.D. (ex officio)<br />

W. James Prowse<br />

Anthony J. Rusciano<br />

Alan S. Schwartz (ex officio)<br />

Nettie H. Seabrooks<br />

Maureen L. Stapleton<br />

Jane R. Thomas, Ph.D.<br />

Manuel Valdivieso, M.D.<br />

Antoinette J. Wozniak, M.D. (ex officio)<br />

George Yoo, M.D. (ex officio)


06<br />

CONTENTS<br />

2 FEATURES<br />

A NEW WAY FORWARD<br />

New president & CEO poised to take<br />

<strong>Karmanos</strong> to next level<br />

10<br />

FIGHTING CANCER WITHOUT FEAR<br />

“The doctors at <strong>Karmanos</strong> are amazing.”<br />

– <strong>Cancer</strong> survivor David Lepper<br />

THE IMPORTANCE OF EARLY DETECTION<br />

WDIV Local 4 meteorologist shares his success story<br />

8 COMPASSIONATE CARE<br />

GETTING THE RIGHT DIAGNOSIS<br />

Identifying environmentally caused cancers<br />

12<br />

DRIVING FORCE<br />

Pancreatic cancer survivor forms<br />

Sky Foundation to further research and awareness<br />

12 AT KARMANOS<br />

A PARTY IN PINK<br />

<strong>Karmanos</strong> presents Komen Detroit Race for the Cure®<br />

UP CLOSE<br />

Connie Claybaker, B.A., MBA<br />

Vice President of Research Administration<br />

WE ALL START SOMEWHERE<br />

Medical staff talks about first jobs<br />

18<br />

ADVANCING CANCER SCIENCE<br />

The Partners – a dedicated group of volunteers raising funds<br />

20 AROUND TOWN<br />

21 Kroger’s Acts of Kindness<br />

A tremendous force in the fight against cancer


HOPE | FEATURE<br />

A New Way<br />

On Feb. 1, the <strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong> entered<br />

a new era as it introduced Gerold Bepler, M.D., Ph.D.,<br />

as its new president and chief executive officer. Dr. Bepler<br />

is a noted thoracic oncologist who was previously director<br />

of the Comprehensive Lung <strong>Cancer</strong> Center at the Moffitt<br />

<strong>Cancer</strong> Center in Tampa, Fla.<br />

Dr. Bepler spoke with HOPE about his vision for<br />

<strong>Karmanos</strong> and the future of cancer care. He also offered a<br />

glimpse of his personal life and how he entered medicine.<br />

Q: What attracted you to the position? Why did you want<br />

to lead <strong>Karmanos</strong>?<br />

A: My goal has always been to lead an institution that is<br />

solely focused on cancer care. But I didn’t want it to be<br />

just anywhere – I wanted to go to a place that can make<br />

a significant impact on cancer. <strong>Karmanos</strong> is one of those<br />

places. It offers solid clinical care, it has all the elements<br />

to discover new cancer therapies and it has the tools to<br />

translate those therapies directly to patient care.<br />

Q: What are your top priorities as<br />

the new President and CEO?<br />

A: First, to develop the next generation<br />

of cancer treatments.<br />

Second, given the uniqueness<br />

of our patient demographics,<br />

reduce cancer disparities. Third,<br />

facilitate access to top of the<br />

line cancer care, for example, by<br />

bringing the latest advances in<br />

cancer care closer to home<br />

for suburban patients at our<br />

treatment center in Farmington<br />

Hills, the <strong>Karmanos</strong>-Crittenton<br />

<strong>Cancer</strong> Center in Rochester<br />

Hills, and the Huron Valley-<br />

Sinai Hospital Charach<br />

<strong>Cancer</strong> Treatment Center in<br />

Commerce. Construction begins<br />

2 | HOPE<br />

Forward<br />

New President and CEO is Poised to Take <strong>Karmanos</strong> to the Next Level<br />

GEROLD BEPLER, M.D., Ph.D.<br />

Title:<br />

President and Chief Executive Officer<br />

Age: 53<br />

Birthplace: Giessen, Germany<br />

Education:<br />

M.D., Ph.D., Philipps University School of<br />

Medicine and Dentistry, Marburg, Germany.<br />

Postdoctoral fellowships completed at the<br />

National <strong>Cancer</strong> <strong>Institute</strong>, Philipps University<br />

and the Duke University Medical Center.<br />

Current residence:<br />

Bloomfield Township<br />

Family:<br />

Wife, Tracey; children Tristan, 18,<br />

Breiton, 12, Isabelle, 9, and Christian, 6.<br />

Hobbies:<br />

Family activities, do-it-yourself home<br />

repairs and projects.<br />

Favorite composers and musicians:<br />

Beethoven, J.S. Bach, Schubert, the Red Hot<br />

Chili Peppers, Queen, Phil Collins, Sting,<br />

and Sarah Brightman.<br />

soon for another cancer center in Monroe. We want to<br />

leverage these outreach initiatives to bring the next generation<br />

of cancer care to patients across the region.<br />

Q: Can you describe your current research efforts?<br />

A: I’m focused on discovering and validating molecules<br />

useful for therapeutic decision making in patients, which<br />

is often called personalized medicine. An increasing<br />

amount of information is available about the molecular<br />

profile of tumors and we have better tools to analyze<br />

those tumors. Together, these components will ultimately<br />

lead to better up-front selection of cancer treatments<br />

for each patient; i.e., to avoid potential toxicity from<br />

less effective treatment and to achieve maximum effect<br />

of available therapies.<br />

Q: How will <strong>Karmanos</strong> elevate its care to the next level?<br />

A: We’ll place a priority on building team science –<br />

bringing scientists with different areas of expertise<br />

together for group research projects. This follows the<br />

same concept as our multidisciplinary<br />

team approach to cancer<br />

treatment, only from a research<br />

perspective. We will apply for<br />

team science grants, such as<br />

the National <strong>Cancer</strong> <strong>Institute</strong>sponsored<br />

SPORE (Specialized<br />

Program of Research Excellence)<br />

grants, which are intended to<br />

support a strong collaboration<br />

between scientists and clinicians.<br />

These collaborations will foster<br />

research that can be translated<br />

into improved cancer diagnosis<br />

and treatment.<br />

Q: In your view, what separates<br />

<strong>Karmanos</strong> from other hospitals<br />

in our area that also provide<br />

cancer treatment?


HOPE | FEATURE<br />

Gerold Bepler, M.D., Ph.D<br />

A: <strong>Karmanos</strong> is one of only 40 National <strong>Cancer</strong> <strong>Institute</strong>designated<br />

comprehensive cancer centers in the United<br />

States. As part of this, we offer a Phase I Clinical Trials<br />

Program [which tests newly developed cancer-fighting<br />

drugs]. Dr. Patricia LoRusso, who leads the program,<br />

has helped build it into one of the best Phase I<br />

programs in the world. <strong>Karmanos</strong> patients have access<br />

to new medications that are not available at community<br />

hospitals. We can match patients to a particular clinical<br />

trial, which is part of our personalized medicine model.<br />

Q: What inspired you to become a doctor?<br />

A: When I was growing up, I wanted to be a musician,<br />

not a physician. I played the piano and wound up studying<br />

at the music conservatory in Frankfurt. But I soon realized<br />

I’d never reach the level of the other students around me.<br />

I had always liked mathematics, biology and physics, so<br />

I gravitated toward medicine. One of my idols was Albert<br />

Schweitzer, a musician and theologian who became a<br />

physician (http://www.albertschweitzer.info).<br />

Q: Why did you choose to enter oncology?<br />

A: Oncology was intellectually stimulating. There wasn’t<br />

as much known about cancer at the time. I thought it<br />

was an incredible challenge. Combining molecular<br />

biology with basic science and patient care is fascinating.<br />

Q: Why did you decide to practice medicine in the United<br />

States instead of your native country?<br />

A: The opportunities are much greater in the U.S. than in<br />

Germany. There are many top-notch universities and<br />

research facilities here. And the U.S. has always been at<br />

the forefront of cancer research.<br />

Q: Has anyone in your family been touched by cancer?<br />

A: Yes. My grandfather died of leukemia, and my father<br />

has leukemia. He’s doing well, and I continue to provide<br />

long-distance care to him.<br />

Q: What message do you want to relay to <strong>Karmanos</strong> patients<br />

and their families?<br />

A: There is hope. Newly-diagnosed patients have many<br />

different treatment options today – there are new<br />

ways to approach the disease through surgery and<br />

radiological intervention, and there are new cancerfighting<br />

drugs. We’re making new discoveries every<br />

day, which will one day lead to the end of this disease.<br />

HOPE | 3 HOPE | 3


HOPE | FEATURE<br />

Fighting <strong>Cancer</strong><br />

without Fear<br />

<strong>Karmanos</strong> Physicians Help Patient<br />

Face the Disease with Confidence<br />

“People shouldn’t be afraid of<br />

cancer, because in many cases it<br />

can be successfully treated. There<br />

are great therapies available<br />

for cancer patients today.<br />

And the doctors at <strong>Karmanos</strong><br />

are amazing.<br />

— David Lepper<br />

4 | HOPE


HOPE | FEATURE<br />

At first, David Lepper thought the small bump<br />

just below his right ear was nothing to worry about.<br />

“My doctor noted it during my annual physical,” says<br />

Lepper, 57, a fundraising consultant from Trenton. “It<br />

was a small, hard bump about the size of a pea. My doctor<br />

thought it was best to have a biopsy performed, and I’m<br />

sure glad I did.”<br />

In July 2003, Lepper’s radiologist performed a biopsy and<br />

diagnosed him with parotid mucoepidermoid carcinoma,<br />

an aggressive cancer that affects the head and neck area.<br />

After receiving the diagnosis, Lepper knew exactly where<br />

he wanted to go for treatment.<br />

“I referred myself to the <strong>Karmanos</strong> <strong>Cancer</strong> Center because<br />

I had previously worked in its Development Department,”<br />

he says. “I knew a lot about the high level of care<br />

<strong>Karmanos</strong> physicians provide. I felt very comfortable going<br />

there, knowing that I’d receive top-notch care.”<br />

Lepper says he was especially impressed by <strong>Karmanos</strong>’<br />

multidisciplinary team approach to patient care. Specialists<br />

from each diagnostic, treatment and supportive care<br />

discipline comprise 13 multidisciplinary teams (MDTs)<br />

to ensure that patients are properly diagnosed and receive<br />

the very best treatment. This approach is part of what makes<br />

<strong>Karmanos</strong> one of 40 National <strong>Cancer</strong> <strong>Institute</strong>-designated<br />

comprehensive cancer centers in the United States.<br />

Lepper and his wife met with representatives from<br />

<strong>Karmanos</strong>’ Head & Neck Oncology Multidisciplinary Team.<br />

“I really appreciated the fact that <strong>Karmanos</strong> brought the<br />

team together to discuss my case,” Lepper says. “They helped<br />

me feel confident in my decision to undergo surgery.”<br />

In August 2003, John Jacobs, M.D., professor of otolaryngology<br />

at <strong>Karmanos</strong> and Wayne State University School<br />

of Medicine, performed a complicated five-hour procedure<br />

to remove the tumor from Lepper’s parotid gland. Doing<br />

so required great precision because of the gland’s proximity<br />

to the facial nerve.<br />

“It’s a tricky procedure,” Dr. Jacobs says. “Typically, you<br />

create a flap of skin and elevate it off the patient’s face, then<br />

find the facial nerve. Only then do you remove the tumor.<br />

Damage to the facial nerve can cause your mouth<br />

to droop or prevent you from closing an eye – it would<br />

appear as if you’d had a stroke. With the improvements<br />

made in chemotherapy and radiation therapy, we’ve been<br />

able to perform more conservative surgeries. In David’s case,<br />

we removed the tumor while preserving nerve function.”<br />

Lepper’s tumor was larger than it appeared on the surface<br />

– about 1-1/2 centimeters, or the size of a cherry.<br />

“This type of cancer is not very common,” Dr. Jacobs says.<br />

“There are roughly 40,000 new head and neck cancers<br />

diagnosed in the U.S. each year, and mucoepidermoid is<br />

just a small fraction of that number. Still, it’s regarded as a<br />

high-grade lesion. If unchecked, the tumor can continue<br />

to grow, paralyzing the face and possibly spreading to the<br />

lungs and brain. That’s why it’s critical to get an early<br />

diagnosis. With few exceptions, if the cancer is caught<br />

early enough, we have the tools to help.”<br />

After surgery, Lepper received six months of aggressive<br />

chemotherapy and radiation therapy to destroy any remnant<br />

of the cancer. Since he worked for the Wayne State<br />

University School of Medicine at the time, Lepper usually<br />

walked to his radiation appointments. Finally, in June 2004,<br />

doctors told Lepper he was cancer-free.<br />

“I felt so great at that moment,” Lepper says. “I continue<br />

going to <strong>Karmanos</strong> for my regular checkups, and there’s<br />

been no sign of cancer for six years. I have some minor<br />

numbness in my ear, but otherwise, I feel wonderful.”<br />

Lepper says battling cancer taught him the importance of<br />

setting fear aside and maintaining a positive attitude.<br />

“I’ve always been a pretty positive person, and I had great<br />

confidence in the physicians at <strong>Karmanos</strong>,” he says. “People<br />

shouldn’t be afraid of cancer, because in many cases it can<br />

be successfully treated. There are great therapies available<br />

for cancer patients today. And the doctors at <strong>Karmanos</strong><br />

are amazing. They’re hard-working people who really care<br />

about their patients.”<br />

To learn more about cancer screening and diagnosis or to<br />

make an appointment, call 1-800-KARMANOS.<br />

HOPE | 5


HOPE | FEATURE<br />

The Importance of<br />

Early Detection<br />

WDIV Local 4 Meteorologist Shares<br />

His Story about Battling Testicular <strong>Cancer</strong><br />

Twenty-one years ago, Paul Gross thought he’d be<br />

the least likely person to contract cancer.<br />

“I worked out regularly and had a low-fat, high-fiber<br />

diet,” says Gross, meteorologist and executive producer<br />

of weather on WDIV-TV in Detroit. “I was just 27 at<br />

the time. So when I learned I had cancer, it was surprising.<br />

I went through a roller coaster of emotions.”<br />

Gross’ urologist diagnosed him with an aggressive form<br />

of testicular cancer. And as with many cases of the disease,<br />

Gross felt no pain.<br />

“I noticed that my left testicle was getting larger and my<br />

jeans were getting tighter in that area,” Gross says. “I didn’t<br />

even know you could get cancer there, but I knew it was<br />

important to have it checked out.”<br />

Gross’ academic training helped him take a scientific<br />

approach to tackling his disease. He has a Bachelor of<br />

Science degree from the University of Michigan’s<br />

Department of Atmospheric, Oceanic and Space Science.<br />

“I learned that my type of cancer cell was very responsive<br />

to the chemotherapy that was available,” he says. “I just<br />

dove into treatment and focused on solving the problem.”<br />

In February 1989, Gross underwent surgery, and then<br />

four rounds of aggressive chemotherapy to destroy a<br />

secondary tumor located in the lymph nodes behind his<br />

left kidney. He was treated at a Detroit hospital affiliated<br />

with the Michigan <strong>Cancer</strong> Foundation, now known as the<br />

<strong>Karmanos</strong> <strong>Cancer</strong> Center.<br />

“The chemo worked very well,” Gross says. “Within two<br />

days of treatment, I could literally feel the tumor shrinking.<br />

I continued with regular checkups every six months. Finally,<br />

11 years after the initial diagnosis, my oncologist looked over<br />

my blood work and discharged me. I was always confident<br />

that I’d beat the disease. Being discharged brought a sense<br />

of finality and created a kind of exclamation point. I could<br />

move forward with my life.”<br />

Dangerous, but Curable<br />

Compared with other cancers, testicular cancer is rare.<br />

But it is still the most common form of solid tumor cancer<br />

in American males between the ages of 15 and 34, says<br />

Ulka Vaishampayan, M.D., team leader of <strong>Karmanos</strong>’<br />

Genitourinary Oncology Multidisciplinary Team and<br />

associate professor of internal medicine at the Wayne State<br />

University School of Medicine.<br />

“Very few patients present with testicular pain – just<br />

swelling in that area,” Dr. Vaishampayan says. “Because<br />

this type of cancer is so aggressive, it’s very important to<br />

have any testicular mass checked right away. The mass can<br />

become much larger within a month or two.”<br />

Dr. Vaishampayan adds that testicular cancer is among<br />

the more treatable forms of cancer even in the advanced<br />

stages, but the cure rate is much better when the cancer<br />

is caught early.<br />

“This type of tumor is very sensitive to chemotherapy and<br />

radiation therapy,” she says. “The chances of being cured<br />

drop when the disease is detected at an advanced stage. But<br />

on average, about 75 percent of patients can be completely<br />

cured. It’s essential that patients see a urologist with an<br />

expertise in oncology and seek treatment at a place that<br />

offers a multidisciplinary approach to patient care.”<br />

A common misconception about testicular cancer is that<br />

a man cannot lead a normal life after treatment,<br />

Dr. Vaishampayan says.<br />

“There is a chance that a man cannot have children following<br />

chemotherapy, but this is not common,” she says. “This is<br />

one cancer that is a prime example of research making a huge<br />

difference in people’s lives and these young men, if treated<br />

correctly, have a very high possibility of leading normal,<br />

productive lives. One example is the case of [cyclist] Lance<br />

Armstrong. He maintained his athletic capacity after treatment<br />

for testicular cancer. Men like him who are willing to<br />

speak about this disease are a source of inspiration for others.”<br />

6 | HOPE


HOPE | FEATURE<br />

Paul Gross<br />

Having an Open Discussion<br />

Since beating testicular cancer, Gross, like Armstrong, has<br />

supported efforts to raise awareness about the disease. In June,<br />

Gross will be the emcee of <strong>Karmanos</strong>’ sixth-annual Survivorship<br />

Celebration, which honors cancer survivors and gives<br />

them the chance to rejoice in having beaten the disease.<br />

“I’m honored to be the emcee of the event,” he says. “No<br />

one is happy that they had cancer, but I’ve found something<br />

positive to take away from the experience. If I can help<br />

inspire one person to get through their own struggle with<br />

cancer by telling my story, then I’ve done my job.”<br />

Gross also says there’s no need for men to feel ashamed<br />

about testicular cancer or avoid the subject.<br />

“Our society has no problem talking about breast cancer,<br />

so why should we be squeamish about discussing testicular<br />

cancer?” Gross asks. “The fact is, it’s the most common cancer<br />

to hit men in the prime of their lives. But it’s also curable<br />

when caught early enough. My message is the importance<br />

of early detection – be aware of your body and don’t be<br />

afraid to go to the doctor. If you need treatment, effective<br />

therapies exist.”<br />

For more information about testicular self exams or<br />

to make an appointment, visit www.karmanos.org or<br />

call 1-800-KARMANOS.<br />

<strong>Karmanos</strong> to honor<br />

<strong>Cancer</strong> Survivors<br />

As any cancer survivor will tell you,<br />

beating the disease requires great<br />

inner strength and a positive outlook. To honor survivors<br />

and their families for their amazing resiliency and fortitude,<br />

<strong>Karmanos</strong> is holding its sixth annual Survivorship<br />

Celebration on June 17 from 5:30-8 p.m. at the Silver<br />

Garden Conference Center in Southfield. WDIV<br />

Local 4’s Paul Gross will emcee the event.<br />

“There are always months designated toward raising<br />

awareness of particular cancers, but those are national<br />

in scope and more medically focused,” says Kelly Brittain,<br />

director of Patient Community Education and Support<br />

Services at <strong>Karmanos</strong>. “The Survivorship Celebration is an<br />

uplifting occasion that allows <strong>Karmanos</strong> cancer survivors<br />

and their supporters to enjoy their triumph over the<br />

disease.” During the event, <strong>Karmanos</strong> will present the<br />

Patricia Milner Sachs Heart of a Survivor Award to a<br />

survivor who shows great compassion, commitment, spirit<br />

and courage in helping others fight cancer. The award is<br />

named after a <strong>Karmanos</strong> employee who lost her 11-year<br />

battle with melanoma in June 2006.<br />

The Survivorship Celebration is free and tickets are not<br />

required. For more information about the event, call<br />

1-800-KARMANOS or visit <strong>Karmanos</strong>.org.<br />

HOPE | 7


COMPASSIONATE CARE<br />

Getting the<br />

Right Diagnosis<br />

<strong>Karmanos</strong> Raises Awareness of Environmentally Caused <strong>Cancer</strong>s<br />

Sometimes asking the right questions makes<br />

all the difference.<br />

That’s what Barb Van Haren of West Bloomfield<br />

discovered after spending years going from doctor to<br />

doctor trying to determine the cause of a persistent cough.<br />

Frustrated by her unresolved illness, Van Haren visited<br />

Michael Harbut, M.D., MPH, FCCP, co-director of<br />

<strong>Karmanos</strong>’ National Center for Vermiculite and Asbestos-<br />

Related <strong>Cancer</strong>s, and professor of internal medicine at<br />

Wayne State University School of Medicine. As an expert<br />

in the diagnosis and treatment of environmentally caused<br />

cancers, Dr. Harbut asked Van Haren questions related to<br />

possible exposure to toxins.<br />

As it turned out, Van Haren had Stage I lung cancer,<br />

possibly caused by exposure to asbestos as a child. Through<br />

a mixture of clinical experience and knowledge of environmental<br />

agents, <strong>Karmanos</strong> physicians caught Van Haren’s<br />

cancer early enough to save her life. She underwent<br />

surgery to remove a nodule in her right lung in May 2007.<br />

Today she is cancer-free.<br />

“Dr. Harbut is my guardian angel,” says Van Haren, 61. “Not<br />

many doctors have the knowledge of environmentally caused<br />

cancer. Several doctors I visited told me my illness was all in<br />

my head. But Dr. Harbut really listened to me. He was very<br />

detailed and thorough in compiling my medical history. If<br />

he wasn’t as persistent about my case, had he not asked me<br />

the right questions, I’d have lung cancer today.”<br />

Environmental Factors<br />

When Van Haren first saw Dr. Harbut about her cough in<br />

early 2007, he performed tests that revealed chronic allergy<br />

and inflammation issues. He placed her on antibiotics, but<br />

also ordered a CT scan because of what he learned about<br />

her history.<br />

“I lived in a basement apartment in Chicago until I turned<br />

six,” Van Haren says. “We had to walk through the furnace<br />

room to get to our apartment, so there’s a chance that I was<br />

exposed to asbestos. I never smoked, but my mother was<br />

a chain smoker, so I was exposed to second-hand smoke<br />

through age 18.”<br />

An initial CT scan showed a nodule on Van Haren’s right<br />

lung and doctors placed her on more antibiotics. When<br />

a subsequent CT scan showed the nodule had grown,<br />

<strong>Karmanos</strong>’ Thoracic Oncology Multidisciplinary Team<br />

reviewed her case and recommended surgery. After a biopsy<br />

showed that the nodule was cancer, <strong>Karmanos</strong> surgeons<br />

removed the lower lobe in her right lung.<br />

“Technically, I’ve been cancer-free since that surgery,”<br />

Van Haren says. “Because it was caught so early, I didn’t<br />

have to do chemo or radiation therapy. I was overwhelmed<br />

with joy when I learned the cancer was gone.”<br />

Raising the Standard of Care<br />

“Mrs. Van Haren’s case is a great example of the intersection<br />

of various disciplines that should be part of 21st<br />

century health care,” Dr. Harbut says. “We not only applied<br />

basic clinical science, but also epidemiology, enhanced<br />

radiographic techniques and tenacity. We didn’t dismiss her<br />

case – instead we kept looking to find the cause of her<br />

symptoms. Her remote exposure to asbestos and<br />

CT scans raised the likelihood of her having cancer.<br />

And as the biopsy showed, it was.”<br />

To help more physicians learn how to identify cancers<br />

caused by environmental exposures in their earliest stages<br />

or before they begin, in January Dr. Harbut created and<br />

launched <strong>Karmanos</strong>’ Environmental <strong>Cancer</strong> Initiative, in<br />

partnership with Blue Cross Blue Shield of Michigan and<br />

the U.S. Centers for Disease Control’s Agency for Toxic<br />

Substances and Disease Registry.<br />

According to Dr. Harbut, asbestos and cigarette exposures<br />

individually confer a five- to 10-fold increased risk of lung<br />

cancer, but exposure to both increases that number to a<br />

54- to 90-fold increased risk.<br />

“Michigan has a higher rate of lung cancer than other<br />

states, and recent data suggests that more than 30 percent<br />

of lung cancers are caused by environmental agents after<br />

controlling for smoking,” Dr. Harbut says.<br />

8 | HOPE


COMPASSIONATE CARE<br />

“The three major environmental<br />

agents that<br />

contribute to this are<br />

asbestos in products like<br />

insulation, arsenic in<br />

drinking water and radon<br />

gas that can seep through<br />

basement walls. We want<br />

to elevate the standard<br />

of care pertaining to the<br />

diagnosis and treatment<br />

of patients with exposure<br />

to these toxins.”<br />

The Environmental <strong>Cancer</strong><br />

Initiative consists of four,<br />

hour-long online courses<br />

that give physicians the<br />

diagnostic tools to identify<br />

patients at risk before<br />

symptoms become apparent.<br />

There is no<br />

charge to enroll and<br />

Blue Cross compensates<br />

physicians for their<br />

time with an incentive<br />

payment upon completion<br />

of the course. The program<br />

is the first of its kind in<br />

the country.<br />

“Environmental cancers can<br />

be very aggressive,” Dr. Harbut says. “That’s why early<br />

detection is imperative. Patients should not dismiss<br />

unexplained symptoms that may be associated with certain<br />

environmental cancer-causing agents. When in doubt,<br />

check it out.”<br />

Van Haren concurs with Dr. Harbut’s advice.<br />

Barb Van Haren<br />

“Don’t ignore symptoms like a persistent cough – get it<br />

diagnosed early,” she says. “I’m very fortunate to be in the<br />

care of <strong>Karmanos</strong> doctors,” she says. “Not only are they<br />

among the best in the country, they take the time to listen<br />

to me and provide top-notch care.”<br />

For more information on the Environmental <strong>Cancer</strong><br />

Initiative, visit www.karmanos.org and click on the<br />

“Education” tab.<br />

HOPE | 9


COMPASSIONATE CARE<br />

Driving<br />

FORCE<br />

<strong>Cancer</strong> Survivor<br />

Supports Research<br />

for Early Pancreatic<br />

<strong>Cancer</strong> Test<br />

According to the National <strong>Cancer</strong><br />

<strong>Institute</strong>, more than 42,000 people will<br />

be diagnosed with pancreatic cancer this<br />

year and more than 35,000 patients will die<br />

from the disease. Pancreatic cancer and its<br />

mortality rates have changed little in the<br />

past three decades – the five-year survival<br />

rate is just five percent.<br />

This cancer is particularly deadly because<br />

its symptoms are initially subtle and often<br />

attributed to other ailments. Because the<br />

pancreas is located in the center of the<br />

abdomen deep inside the body, it’s often<br />

difficult to identify the disease at an early<br />

stage. In many cases, by the time the disease<br />

is correctly diagnosed, the cancer has spread<br />

to the patient’s lymph nodes, liver or lungs,<br />

significantly reducing the chance for a cure.<br />

As with all cancers, getting an early diagnosis<br />

is critical. And researchers at the <strong>Karmanos</strong><br />

<strong>Cancer</strong> <strong>Institute</strong>, the Wayne State University<br />

School of Medicine and Henry Ford Health<br />

System are working together to develop<br />

a new blood test that will help detect<br />

pancreatic cancer at an early stage.<br />

Sheila sky kasselman<br />

Sheila Sky Kasselman, a tenacious<br />

pancreatic cancer survivor from West<br />

Bloomfield, is a driving force behind the<br />

research. As she recovered from cancer<br />

surgery in 2008, she began raising the<br />

funds necessary to launch the project.<br />

10 | HOPE


COMPASSIONATE CARE<br />

Steve Dudas, Ph.D.<br />

Photo by Brad Kasselman<br />

True to Her Promise<br />

Kasselman had dealt with various ailments for about<br />

a year before doctors determined their true cause.<br />

Fortunately, her disease was diagnosed at Stage 1 –<br />

early enough for successful treatment.<br />

“I had lost 12 pounds in a month, and I normally<br />

weigh about 110,” says Kasselman, 69, a retired financial<br />

planner. “Then I developed diabetes and became<br />

jaundiced. A CT scan in October 2007 revealed a<br />

tumor at the head of my pancreas.”<br />

Kasselman underwent simultaneous chemotherapy<br />

and radiation therapy for six weeks to shrink the tumor.<br />

In January 2008, surgeons removed the tumor in a<br />

10-hour procedure that impacted her pancreas, small<br />

intestine, bile duct and stomach.<br />

“I was told that it was a very involved, high-risk surgery,”<br />

Kasselman says. “But I remained mentally strong. In my<br />

diary I wrote, ‘I’m not going to die. I have way too much to<br />

accomplish.’ I made a promise to myself and my family that<br />

I would do everything I could to challenge this disease.”<br />

Kasselman has remained true to her promise. While<br />

recovering from surgery, she formed the Sky Foundation<br />

to help increase awareness of pancreatic cancer and raise<br />

funds to help researchers find better ways of diagnosing<br />

the disease. Through her Henry Ford Hospital gastroenterologist,<br />

Ann Silverman, M.D., Kasselman learned<br />

about the research underway at <strong>Karmanos</strong>.<br />

Early Stage Biomarkers<br />

Michael Tainsky, Ph.D., leader of <strong>Karmanos</strong>’ Molecular<br />

Biology and Genetics Program and professor in<br />

the Department of Pathology at the Wayne State<br />

University School of Medicine, had spent seven years<br />

researching diagnostic biomarkers for ovarian cancer.<br />

Inspired by Kasselman’s enthusiasm and drive to help<br />

pancreatic cancer patients, Dr. Tainsky and his team<br />

began working with Dr. Silverman on developing an<br />

early detection blood test.<br />

“We’re using the same approach we applied when<br />

researching ovarian cancer biomarkers,” says Research<br />

Associate Steve Dudas, Ph.D., a member of Dr. Tainsky’s<br />

research team. “We’re collecting serum samples from a<br />

number of bio-repositories and through the National<br />

<strong>Cancer</strong> <strong>Institute</strong>’s Early Detection Research Network.<br />

We basically look for profiles of cancer-associated<br />

auto-antibodies in the blood that would be indicative<br />

of a malignancy in the pancreas. Identifying these<br />

auto-antibodies as cancer biomarkers will help us<br />

develop an advanced screening blood test.”<br />

Dr. Dudas says the Sky Foundation was instrumental<br />

in launching the project.<br />

“We’ve worked with the foundation almost since its<br />

inception to raise the funds needed to begin the discovery<br />

phase of our research,” he says. “It takes time and money<br />

to launch a study of this magnitude. We’re optimistic<br />

that we’ll carry our work forward to the point where<br />

we can apply for additional funding from the National<br />

<strong>Institute</strong>s of Health.”<br />

Thus far, the Sky Foundation has raised about $165,000<br />

and continues to advance toward its initial $500,000<br />

fundraising goal. The foundation has become a labor<br />

of love for Kasselman.<br />

“I’m very fortunate to be one of the few people who<br />

survive the disease,” she says. The foundation is my way<br />

of giving back – we want to supply hope for patients, as<br />

well as solid scientific data. We have tremendous faith<br />

in the research team and their collaborative efforts to<br />

develop a diagnostic tool that will save lives.”<br />

To get involved or to make a contribution, call the<br />

Sky Foundation at 248-978-9845 or the <strong>Karmanos</strong><br />

<strong>Cancer</strong> <strong>Institute</strong> at 313-576-8119. You can also visit<br />

skyfoundationinc.org. For more information about cancer<br />

services, call 1-800-KARMANOS or visit <strong>Karmanos</strong>.org.<br />

HOPE | 11


AT KARMANOS<br />

A Party<br />

in Pink<br />

Woodward Avenue in Midtown Detroit is never<br />

more beautiful than the day it’s decked out for the Susan<br />

G. Komen Detroit Race for the Cure®. About 30,000<br />

people descend upon Comerica Park each year to increase<br />

breast cancer awareness, celebrate survivorship and raise<br />

much-needed funds to support local breast cancer<br />

education, screening programs and cancer research.<br />

This year’s race, scheduled for Saturday, May 22, will be<br />

the 19th annual event.<br />

“The Komen Detroit Race for the Cure is a big<br />

Detroit party for the entire family,” says Maureen<br />

Keenan Meldrum, race chair and director of Breast<br />

<strong>Cancer</strong> Special Programs at the <strong>Karmanos</strong> <strong>Cancer</strong><br />

<strong>Institute</strong>. “Our job is to keep it fresh and wonderful.<br />

We promise the same mix of traditions that people<br />

have come to love about our race, as well as some cool<br />

new surprises.”<br />

Despite the tough economy, last year’s event raised<br />

just over $2 million. Each year, 75 percent of the proceeds<br />

remain within the local community for breast cancer<br />

screening and treatment programs for medically<br />

underserved populations. The remaining funds support<br />

breast cancer research grants for projects across the globe,<br />

including work underway at <strong>Karmanos</strong>.<br />

The theme of the <strong>2010</strong> race is “The Power of 10.”<br />

Organizers are encouraging race participants to increase<br />

their involvement with actions like asking 10 more people<br />

to make a donation or telling 10 more women about the<br />

importance of mammograms.<br />

<strong>Karmanos</strong> <strong>Cancer</strong> Center Mammography Screening Guidelines<br />

Last November, the United States Preventative<br />

Services Task Force issued new breast cancer<br />

screening guidelines that were met with some<br />

controversy. <strong>Karmanos</strong> <strong>Cancer</strong> Center breast<br />

cancer specialists are not adopting these new<br />

guidelines. <strong>Karmanos</strong> recommends that:<br />

1. Beginning at age 40, women should speak<br />

to their doctors about mammography to<br />

understand the potential benefits and risks,<br />

and determine what is best for them.<br />

Though mammography is not perfect, it<br />

remains the best tool for physicians to detect a tumor<br />

that is too small to be felt.<br />

2. Continue with self-breast exams. Women need to be<br />

familiar with their bodies and immediately contact their<br />

physician if they detect a lump or other abnormality.<br />

3. Discussions about the new guidelines do not apply<br />

to women who are considered to be of high risk for<br />

breast cancer. This includes, but is not limited to:<br />

• Anyone with a strong family history of breast cancer.<br />

• Women with a history of breast cancer.<br />

• Women who detect a lump in their breast.<br />

12 | HOPE


AT KARMANOS<br />

May 22 Marks the 19th Annual Komen Detroit Race for the Cure ®<br />

“At first, I went to the<br />

event to support my mom.<br />

But I also found that<br />

going helps build you<br />

up – and you need a lot<br />

of support when you<br />

face cancer.<br />

— Sherry Thrower<br />

HOPE | 13


AT KARMANOS<br />

“Everyone knows someone who has been<br />

touched by breast cancer,” Meldrum says. “As<br />

a breast cancer survivor myself, I know how<br />

comforting it is to become involved with the race.<br />

The biggest thing participants take away from<br />

the event is tremendous optimism from seeing so<br />

many pink shirts and happy cancer survivors.”<br />

One of those survivors is Sherry Thrower of Detroit.<br />

Doctors diagnosed her with breast cancer in 2007 after<br />

a routine mammogram.<br />

“My mother is a three-time cancer survivor, so I<br />

understand the importance of regular mammograms,”<br />

says Thrower, 43. “She was treated at <strong>Karmanos</strong>, so I was<br />

very comfortable seeing them for a second opinion. They<br />

concurred with the first diagnosis, and I had chemotherapy,<br />

a mastectomy and radiation therapy in 2008. Now, I’m<br />

cancer-free. I had an awesome team of doctors and<br />

they were always positive. I’d recommend them for their<br />

expertise and attitude.”<br />

Thrower has attended the last three Komen Detroit<br />

Race for the Cure events with her mother.<br />

“At first, I went to the event to support my mom. But I<br />

also found that going helps build you up – and you need<br />

a lot of support when you face cancer. I heard many<br />

wonderful stories about survivorship at the race. It’s a<br />

very uplifting, positive event.”<br />

For Early Detection,<br />

Get a Mammogram<br />

As with all cancers, early detection is the key. And one of the most valuable tools<br />

for an early breast cancer diagnosis is a mammogram.<br />

“Early diagnosis not only results in a lower death rate, but also more treatment options,”<br />

says Sharon Helmer, M.D., clinical service chief of the <strong>Karmanos</strong> <strong>Cancer</strong> Center Imaging<br />

Department and medical director of Breast Imaging. “It opens up the possibility of<br />

conservative therapy for breast conservation. It also gives patients more treatment<br />

options in terms of chemotherapy and radiation therapy.”<br />

Dr. Helmer emphasizes that mammograms aren’t perfect and can sometimes show a<br />

false positive or miss cancers that are present, but it’s still the best method available<br />

for detecting the disease. “It is very important for women to have annual mammograms<br />

beginning at age 40,” she says.<br />

“Until the early 1990s, little progress had been made in decreasing breast cancer<br />

mortality,” Dr. Helmer adds. “But since the development of mammography, the breast<br />

cancer death rate has declined by 30 percent. It’s been extremely successful.”<br />

For further information about mammography screenings, visit karmanos.org<br />

or call 1-800-KARMANOS.<br />

014 | | HOPE


AT KARMANOS<br />

Race Info<br />

WHAT:<br />

The 19th Annual<br />

Susan G. Komen Detroit<br />

Race for the Cure ®<br />

5K Run/Walk and 1-Mile Walk<br />

locally presented by the<br />

<strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong>.<br />

WHEN:<br />

Saturday, May 22,<br />

7-11:30 a.m.<br />

Street closures will begin at 7 a.m.<br />

Opening Ceremony 8 a.m.<br />

Race and walk 9 a.m.<br />

Closing Ceremony 10:30 a.m.<br />

WHERE:<br />

Comerica Park, Detroit.<br />

WHY:<br />

To help save lives and end breast<br />

cancer forever.<br />

FOR MORE<br />

INFORMATION:<br />

karmanos.org/detroitraceforthecure<br />

HOPE | | 15 0


AT KARMANOS<br />

Up Close:<br />

Connie Claybaker, B.A., MBA<br />

Throughout her career spanning 30+ years, Connie<br />

Claybaker has worn a lot of hats. From catalog distribution<br />

center accountant to restaurant owner to her current<br />

role as vice president of Research Administration at the<br />

<strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong>, she’s put many different skills<br />

to work. But through all her career moves, the common<br />

thread is strong leadership.<br />

“I love developing business processes, handling complex<br />

projects and leading people,” says Claybaker, who joined<br />

<strong>Karmanos</strong> in 2003 and assumed her current position last<br />

June. “I’m a people-oriented person who thrives in environments<br />

that support independent thinking and collaboration.”<br />

Claybaker’s department helps <strong>Karmanos</strong> obtain federal,<br />

state, and corporate funding for its research activities, including<br />

clinical trials. The department manages hundreds of<br />

grant proposals and contracts at any one time and provides<br />

administrative support services for the competitive <strong>Cancer</strong><br />

Center Support Grant. This grant is key to <strong>Karmanos</strong>’ designation<br />

as a comprehensive cancer center by the National<br />

<strong>Cancer</strong> <strong>Institute</strong>. <strong>Karmanos</strong> is one of just 40 such centers in<br />

the United States.<br />

“Of those 40 comprehensive cancer centers, only a dozen<br />

or so are stand alone, independent hospitals,” Claybaker<br />

says. “<strong>Karmanos</strong> is one of those and we only treat cancer.<br />

That’s an important distinction, because <strong>Karmanos</strong> patients<br />

know that no matter who they encounter here, that person<br />

gives their undivided attention to curing cancer. Embedded<br />

within that is my job – taking the administrative burden off<br />

our cancer researchers so they can do what they do best.”<br />

Claybaker launched her career in the mid-1970s as a staff<br />

accountant at the J.C. Penney Distribution Center in Columbus,<br />

Ohio. From there, she held accounting and management<br />

positions at various companies before opening a health food<br />

restaurant, the Hip Pocket Deli, in Columbus.<br />

Connie Claybaker (center) with staff members Valerie Wade<br />

and Evano Piasentin in the Leonard N. Simons <strong>Cancer</strong> Research<br />

Library located in <strong>Karmanos</strong>’ Prentis <strong>Cancer</strong> Research Center.<br />

Photo by Gregg W. Hettel<br />

“Running a restaurant was very physical work,” Claybaker<br />

says. “Things like tofu and pickles came in these enormous<br />

tubs that you had to carry. It was physically exhausting work.”<br />

After about two years in the restaurant business, Claybaker<br />

joined Riverside Methodist Hospitals in Columbus to<br />

manage its accounts payable and payroll department.<br />

After advancing to director of Medical Staff Administration,<br />

she knew that working in health care was her true<br />

calling. She moved to Michigan in 1999 and joined<br />

<strong>Karmanos</strong> after managing financial and grant activities at<br />

other health care organizations.<br />

“When you enter health care, it becomes a passion,”<br />

Claybaker says. “I’ve never touched a patient or<br />

administered a drug, but I don’t feel as though I haven’t<br />

made a contribution. Research is much more than just a<br />

mission statement at <strong>Karmanos</strong>. Everyone here is very<br />

passionate about what they do and many people wear<br />

it on their sleeves. That’s infectious. I’m proud of this<br />

organization because it clearly gives itself to patients<br />

for unselfish reasons. It’s clear to me that our work will<br />

one day help someone’s parent or grandparent or loved<br />

one beat this disease.”<br />

[BIO]<br />

Connie Claybaker, B.A., MBA<br />

TITLE: Vice President of<br />

Research Administration<br />

BIRTHPLACE: Coshocton, Ohio<br />

EDUCATION: B.A., Accounting and<br />

Management (Cum Laude); MBA, Capital<br />

University, Columbus, Ohio.<br />

HOME: West Bloomfield<br />

HOBBIES: Golf, reading, going to the movies and<br />

playing with her dog, Buster. “I just began reading<br />

Barbara Kingsolver’s new novel, ‘The Lacuna.’ A<br />

perfect weekend for me is sleeping in, watching a<br />

movie and having dinner with friends.”


We All Start<br />

Somewhere<br />

<strong>Karmanos</strong> Medical Staff Share Stories about Their First Jobs<br />

Sharon Helmer, M.D.<br />

Clinical Service Chief, Imaging Department, Medical Director of <strong>Karmanos</strong> Breast Imaging<br />

“I got my first job at age 16 as a waitress at the Deer Run Golf Club in Horton,<br />

Michigan. Not only did I take the golfers’ orders in the clubhouse, I also prepared the<br />

food in the kitchen and then had to serve and clear the table. I could make incredible<br />

fried onion rings…a skill I often regretted. That job was my first taste of dealing with the<br />

public. I learned a lot that summer about working with people from different backgrounds<br />

and with different expectations. I’ve carried many of those lessons with me – particularly<br />

about treating everyone equally and with respect no matter how they treat you.”<br />

Ho-Sheng Lin, M.D., FACS<br />

Leader, Head & Neck Oncology Multidisciplinary Team<br />

“When I was 16, I worked as a technician in a microbiology laboratory in Ocala,<br />

Florida. This was my dream job because I got to work in a medically related field<br />

and the job sounded cooler than working in a supermarket or fast food restaurant.<br />

However, the job wasn’t very glamorous. Most of the time, I was washing test tubes<br />

and bottles filled with germs. I don’t think they had very good OSHA (Occupational<br />

Safety and Health Administration) regulations back then. However, I did learn some<br />

microbiological techniques and some cool bug names, such as ‘streptococcus.’”<br />

Michael Simon, M.D., MPH<br />

Medical Oncologist<br />

“In the summer after my senior year of high school, I worked evenings and some weekends at a<br />

Baskin-Robbins ice cream store in the Chicago neighborhood where I grew up. During the day,<br />

I was a day camp counselor at the Henry Hart Jewish Community Center. I loved being outside<br />

and working with kindergarten-age children. We often took them to a large park on Chicago’s<br />

north side for various activities. I enjoyed the ice cream shop because friends and family came<br />

regularly for ice cream. Making the various sodas was fun – eventually I learned how to make<br />

some of the more complicated orders.”<br />

Lisa Zajac, MSN, APRN-BC, OCN<br />

Informatics Nursing Specialist<br />

“I got my first job at the Dearborn Toys “ ” Us when I was 17. I started as a “Geoffrey’s<br />

Helper” (helping shoppers on the sales floor), but also worked as a cashier and stocking<br />

shelves. I loved helping a grandparent find a gift for their grandchild during the holiday<br />

season. I also enjoyed working until 2 a.m. straightening the shelves for the next day.<br />

One night we had to re-shelve 140 carts of merchandise that customers left in the<br />

wrong spot. This job really prepared me to be a nurse. I not only learned about providing<br />

excellent customer service, but, at times, I worked days, afternoons and midnights, just<br />

as I’ve done at <strong>Karmanos</strong> through the years.”<br />

HOPE | 17<br />

Photo by Gregg W. Hettel


At karmanos<br />

Advancing<br />

<strong>Cancer</strong> Science<br />

Partners Vigorously Supports <strong>Karmanos</strong> Researchers<br />

Every day, <strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong> scientists<br />

and clinicians break new ground in their search for<br />

better cancer detection and treatment methods. Because<br />

there’s a tremendous cost in terms of equipment and staffing,<br />

funding from sources outside <strong>Karmanos</strong> is essential for<br />

launching and maintaining these exciting research initiatives.<br />

And that’s where fundraising groups like Partners come in.<br />

Partners is a dynamic group of volunteers, ages 25 to 50, who<br />

are dedicated to making an impact in the fight against cancer.<br />

Philanthropists Anna and Harry Korman created Partners<br />

in 1994 in honor of their late daughter, Suzanne, who died<br />

of cancer at age 36. They established a research fund with<br />

the hope of finding better treatments and earlier detection<br />

methods for cancer patients. Since the group’s formation,<br />

it has raised more than $5.6 million for <strong>Karmanos</strong> through<br />

fundraising events and individual donations.<br />

One initiative Partners has supported with $750,000 in<br />

donations over the past five years is <strong>Karmanos</strong>’ National<br />

Oncogenomics and Molecular Imaging Center (NOMIC).<br />

Directed by Principal Investigator Stephen Ethier, Ph.D.,<br />

NOMIC is engaged in developing technology that will<br />

help physicians better diagnose cancer by defining gene<br />

mutations that characterize cancers in individual patients.<br />

This research will one day allow physicians to create highly<br />

customized treatment therapies based on the specific gene<br />

mutations identified in a patient.<br />

“In order to secure federal funding for research, you have<br />

to prove that your project will generate results,” Dr. Ethier<br />

says. “We don’t just spend funds from groups like Partners,<br />

we try to leverage it to obtain more funding. Having the<br />

lab up and running allowed us to obtain federal grants.<br />

“The bottom line is, financial assistance from Partners<br />

doesn’t just support cool science – it helps us take care of<br />

patients in ways never before possible. Our goal is to make<br />

sure we’re bringing the best technology to cancer patients.”<br />

Beyond NOMIC, according to Dr. Ethier, Partners funds<br />

have purchased vital research equipment that ensures<br />

cutting-edge research continues in the research labs, and<br />

ensures that <strong>Karmanos</strong>’ shared resource laboratories always<br />

have state-of-the-art equipment, which is essential to a<br />

strong cancer center. This ultimately benefits the nearly<br />

6,000 new patients who come to <strong>Karmanos</strong> annually for<br />

“We knew we’d have to make a significant investment in<br />

NOMIC in order to meet our research goals,” Dr. Ethier<br />

says. “Partners has been instrumental in helping us launch<br />

the program. Through their generous donations, we’ve been<br />

able to purchase state-of-the-art equipment and attract<br />

cutting-edge researchers. NOMIC simply wouldn’t exist<br />

without their support.”<br />

Partners funding has also helped NOMIC secure more<br />

than $14 million in grants from the U.S. Army Medical<br />

Research and Materiel Command.<br />

18 | HOPE<br />

From left: Ramsi Haddad, Ph.D., director, Laboratory of<br />

Translational Oncogenomics; Raj Atikukke, post-doctoral<br />

fellow, and Irene Broner, lab manager. Photo by Gregg W. Hettel


At karmanos<br />

Photo by Gregg W. Hettel<br />

treatment. As it looks to the future, Partners plans to raise<br />

funds for a laboratory to investigate lung cancer.<br />

“I find it personally rewarding to be part of a group of<br />

young, enthusiastic people dedicated to raising money for<br />

cancer research,” says Dan Cornwell, executive co-chair of<br />

Partners and financial planning consultant. “It’s worthwhile<br />

for me to be part of this group considering cancer has<br />

impacted my family and many of my clients.<br />

“The staff at the <strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong> has always<br />

been generous with time and resources. Partners members<br />

are gratified to know that our efforts make a real difference<br />

to those on the front lines of cancer research. Supporting<br />

<strong>Karmanos</strong> scientists aligns with our group’s goal of one day<br />

bringing cancer under complete control.”<br />

J.J. Modell, who shares the executive co-chair position with<br />

Cornwell, has been a member of the organization for about<br />

10 years and has seen the change that comes about from<br />

the Partners’ efforts.<br />

“During my time with the Partners organization, I have<br />

seen firsthand the wonderful and tremendous progress that<br />

has been made in the fight against cancer,” Modell said.<br />

“Partners members are pleased to know they are helping<br />

bring hope to <strong>Karmanos</strong>’ patients.”<br />

To learn how to become a member of Partners, call<br />

(313) 576-8107 or e-mail partners@karmanos.org.<br />

Upcoming Partners Events<br />

PARTNERS GOLF OUTING<br />

Monday, August 30<br />

Franklin Hills Country Club<br />

Nearly 200 golfers participate in a competitive scramble.<br />

For their generous contributions, guests enjoy a great<br />

day of golf, food, drink and prizes.<br />

PARTNERS NIGHT<br />

Saturday, September 11<br />

Detroit <strong>Institute</strong> of Arts<br />

Partners Night is the group’s signature event. It includes<br />

an incredible silent auction, a raffle, fine strolling savory<br />

fare, and live entertainment and dancing.<br />

For more information on these events, contact the Partners at (313) 576-8107 or partners@karmanos.org.<br />

HOPE | 19


AROUND<br />

town<br />

FUND-RAISING EVENTS<br />

MAY<br />

Horsemen’s Paradise Trail Ride<br />

Saturday, May 15<br />

9 a.m. – 2 p.m.<br />

Belle Isle<br />

North Brothers Ford &<br />

the City of Westland 12th Annual<br />

5K Fun Run/Walk<br />

Saturday, May 15<br />

8 – 11 a.m.<br />

Bailey Recreation Center<br />

36651 Ford Rd, Westland<br />

The $500,000 Odyssey 2-Ball<br />

Putt Challenge presented<br />

by Carl’s Golfland<br />

Saturday, May 15<br />

10:30 a.m. – 2:30 p.m.<br />

Carl’s Golfland<br />

1976 S. Telegraph Rd., Bloomfield Hills<br />

2nd Annual Ken Wood<br />

Memorial Golf Outing<br />

Saturday, May 15<br />

Noon – 5 p.m.<br />

Pheasant Run Golf Course<br />

1150 S. Canton Center Road, Canton<br />

Artunes on the Mountain<br />

Saturday, May 22<br />

11 a.m. – 10 p.m.<br />

Bald Mountain State Recreation Area<br />

1330 East Greenshield Road, Lake Orion<br />

JUNE<br />

Noodles & Company Benefit Night<br />

Thursday, June 3<br />

4 – 9 p.m.<br />

Noodles & Company #8007<br />

470 S. Main Street, Royal Oak<br />

Hank Greenberg Memorial<br />

Golf Invitational<br />

Monday, June 21<br />

Oakland Hills Country Club<br />

3951 W. Maple Road, Bloomfield Hills<br />

<strong>2010</strong> Solstice Run<br />

Saturday, June 26<br />

7 a.m. – Noon<br />

Downtown Northville<br />

JULY<br />

International Dragon<br />

Boats Festival<br />

Friday, July 9 – Sunday, July 11<br />

Windsor, ON<br />

SKIN III<br />

Saturday, July 24<br />

Location to be determined<br />

Three Shots Against <strong>Cancer</strong><br />

Saturday, July 24<br />

8 a.m.<br />

Wyandotte Shores Golf Course<br />

3625 Biddle Avenue, Wyandotte<br />

Ryan O’Donnell Golf Outing<br />

Saturday, July 24<br />

Sycamore Hills Golf Club<br />

48787 North Avenue, Macomb<br />

Torch Lakes Classics Rendezvous<br />

Saturday, July 24<br />

Torch Lake in Bellaire<br />

AUGUST<br />

6th Annual Tammy Z Golf outing<br />

Saturday, August 7<br />

Mystic Creek,<br />

One Champions Circle, Milford<br />

Pummill <strong>Cancer</strong> Golf Classic<br />

Saturday, August 14<br />

The Links at Whitmore Lake<br />

1111 6 Mile Rd, Whitmore Lake<br />

BAPS Charities Annual Walkathon<br />

August 21<br />

8 a.m.<br />

1150 Canton Center Road South, Canton<br />

10th Annual Kenneth J. Scott<br />

Memorial Golf Outing<br />

Sunday, August 22<br />

Fox Hills Golf & Banquet Center<br />

8768 North Territorial Road, Plymouth<br />

Hero Foundation Golf Outing<br />

Saturday, August 28<br />

11:30 a.m. – 5 p.m.<br />

Twin Lakes Golf & Swim Club in Oakland Township<br />

455 Twin Lakes Drive, Oakland Township<br />

Partners Golf<br />

Monday, August 30<br />

Franklin Hills Country Club<br />

31675 Inkster Road, Franklin<br />

20 | HOPE


Kroger’s<br />

Acts of Kindness<br />

Ongoing Donations Fund <strong>Cancer</strong> Research at <strong>Karmanos</strong><br />

As a community partner, the Kroger Company<br />

is a tremendous force in the fight against cancer.<br />

Over the past four years, Kroger’s Michigan Division<br />

has made a strong commitment to supporting cancer<br />

research and patients at the <strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong><br />

and American <strong>Cancer</strong> Society. Each year, Kroger’s<br />

combined in-store promotions raise about $150,000<br />

for <strong>Karmanos</strong>. The funds primarily support ovarian<br />

and breast cancer research.<br />

“Kroger’s primary customers are women between the<br />

ages of 25 and 54, and cancer is one of their biggest health<br />

concerns,” says Dale Hollandsworth of Kroger Consumer<br />

Communications. “We have an obligation to support<br />

initiatives that address those concerns. We welcome the<br />

opportunity to team with a world-class organization<br />

like the <strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong> to improve treatments<br />

for breast and ovarian cancer and even find a cure for<br />

these life-threatening diseases.”<br />

evaluate new cancer-fighting drugs. Kroger plans to<br />

continue providing treats for Phase I patients in the<br />

coming months.<br />

“We are grateful for the extraordinary support of<br />

Kroger and its customers,” says Nick <strong>Karmanos</strong>, vice<br />

president of Development for <strong>Karmanos</strong>. “Kroger’s<br />

continued generosity to provide resources for cancer research<br />

and education is an exceptional example of corporate<br />

partnership and their commitment to this community.”<br />

One in eight women will be diagnosed with breast cancer.<br />

A woman’s risk of getting ovarian cancer in her lifetime<br />

is about one in 67. Early detection is critical to saving<br />

lives and research is a vital component in finding better<br />

ways to diagnose and treat the disease.<br />

If your organization is interested in partnering with<br />

the <strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong>, call 313-576-8111.<br />

In 2006, Kroger launched its Teal Ribbon campaign at<br />

its stores to support the Gail Purtan Ovarian <strong>Cancer</strong><br />

Research Fund at <strong>Karmanos</strong>. Three years ago, Kroger<br />

began raising funds for breast cancer research through<br />

coin box donations at checkout lines, the sale of special<br />

“Recipes for Hope” cookbooks and other promotions.<br />

“Kroger is committed to funding research to help find a<br />

cure for cancer and the <strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong> and<br />

the American <strong>Cancer</strong> Society are uniquely suited to lead<br />

this effort,” says Rick Going, president of Kroger’s<br />

Michigan Division. “We’re thrilled to partner with the<br />

<strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong> and the American <strong>Cancer</strong><br />

Society and hope our donations, through the generous<br />

support from our partners, customers and associates, will<br />

have even more impact on cancer research initiatives.”<br />

Kroger associates also showed their appreciation for<br />

<strong>Karmanos</strong> patients last August when they sent a basket<br />

of Kroger bakery cookies to the Phase I clinical trial unit.<br />

Patients in this unit are enrolled in research studies that


Email: hope@karmanos.org<br />

...................................................<br />

Mary ANn SHort<br />

Vice President,<br />

Marketing and Communications<br />

Linda H. Remington<br />

Editor<br />

Director,<br />

Marketing and Communications<br />

<strong>Karmanos</strong>.org<br />

1-800-KARMANOS<br />

Mail Code: NCO6MC<br />

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DETROIT, MI 48201<br />

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U.S. POSTAGE<br />

PAID<br />

DETROIT, MI<br />

PERMIT NO. 1579<br />

Associate Editors:<br />

Patricia A. Ellis<br />

Media Relations Manager<br />

Elizabeth Katz<br />

External Marketing and Communications Associate<br />

Christine Parker<br />

Internal Marketing and Communications Associate<br />

...................................................<br />

Photos by Stephen Lengnick, Plum Street Studio<br />

Copyright <strong>2010</strong> Barbara Ann <strong>Karmanos</strong> <strong>Cancer</strong> <strong>Institute</strong><br />

Grand Opening<br />

The <strong>Karmanos</strong>-Crittenton <strong>Cancer</strong> Center<br />

The <strong>Karmanos</strong>-Crittenton <strong>Cancer</strong> Center recently<br />

celebrated its grand opening with a ribbon-cutting<br />

ceremony. The new 30,000-square-foot facility brings<br />

state-of-the-art cancer care to patients in Rochester Hills<br />

and the surrounding communities. Photos by David Dalton<br />

“Ford Corporate Flowers” by Chris McCauley - A guest<br />

admires artwork at the cancer center provided by local<br />

artists from Oakland University and Paint Creek Center<br />

for the Arts.<br />

Interior photo of bldg: Photography by Beth Singer Photographer, Inc.<br />

Steve Stolaruk, who donated the land<br />

for this facility, Gerold Bepler, M.D.,<br />

Ph.D., president & CEO, <strong>Karmanos</strong><br />

<strong>Cancer</strong> <strong>Institute</strong>; and Lynn Orfgen,<br />

president & CEO, Crittenton Hospital<br />

Medical Center, cut the ribbon.

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