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JC. Le Huec - ArgoSpine

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SAGITTAL BALANCE AND TDR:<br />

WHAT IS THE BEST CHOICE<br />

J-C <strong>Le</strong> <strong>Huec</strong> M.D.Ph.D.*<br />

*Chairman SPINE UNIT,<br />

orthopaedic department<br />

Dir. surg research lab<br />

BORDEAUX university, France,<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


THE PELVIS S IS THE<br />

BASEMENT<br />

:<br />

anatomical<br />

Pelvic Parameters<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY<br />

C.<br />

.<br />

S


<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY<br />

C.<br />

S<br />

.


<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY<br />

C.<br />

.<br />

S


<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY<br />

C.<br />

.<br />

S


SS<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY<br />

- PELVIC TILTING and SACRAL SLOPE are<br />

variable positional parameters<br />

PT<br />

SS<br />

PI<br />

PT


Duval-Beaupère & al.<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


Harmonious alignment of the trunk<br />

Anatomical parameters !!!<br />

Allows to stand spending<br />

the least amount of<br />

energy ++++<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


Biomechanical analysis<br />

of the shape of the spine<br />

NO MORE<br />

anatomical based<br />

The french revolution<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


NEW WAY TO ANALYSE SAGITTAL PLAN<br />

Software analysis to help to analyse contour<br />

CC<br />

THORACIC<br />

KYPHOSIS<br />

TC<br />

Inflexion point<br />

Superior arch<br />

LUMBAR<br />

LORDOSIS<br />

spine balance angle<br />

Apex<br />

β<br />

θ<br />

LL<br />

inferior arch<br />

PT<br />

PI<br />

SS<br />

OPTISPINE<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY<br />

EOS DEVICE<br />

2 mtres<br />

2 mtres<br />

ENTREE<br />

Passage<br />

ENTREE<br />

425 mm<br />

BIOSPACE-


THE EOS SYSTEM<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY<br />

EFFECT OF THE INCIDENCE<br />

ANGLE ON THE SHAPE OF<br />

LORDOSIS


PI = 41°<br />

LL = 52°<br />

GLOBAL RESULTS<br />

PI = 44°<br />

LL = 52°<br />

TYPE 1 SS < 35°<br />

TYPE 2 SS < 35°<br />

PI = 51°<br />

LL = 61°<br />

35°< SS < 45°<br />

TYPE 3<br />

PI = 63°<br />

LL = 71°<br />

TYPE 4 SS > 45°<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY<br />

1) Shape of Lordosis depends on Sacral Slope<br />

Type 3<br />

Type 1 Type 2<br />

Type 4


C7 plumb line and Sacral slope<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


C7 plumb line and Sacral slope<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


CONCLUSION<br />

Lumbar lordosis is highly correlated with<br />

pelvic parameters<br />

and particularly sacral slope<br />

Respect or restoration of lordosis is<br />

crucial<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


Effect of one level TDR on saggital alignment<br />

<strong>Le</strong> huec jc, Basso y, Eur Spine J, 2005<br />

Prospective study design:<br />

Total disc prosthesis restore: motion, disc height, and<br />

finally function close to anatomy<br />

Study design: to determine the effect of single level TDA<br />

on sagital balance<br />

the idea: this can protect accelerated DDD at adjacent<br />

levels or improve back pain<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


Material and Method<br />

CC<br />

1. Global lordosis- angle upper endplate of L1<br />

and the sacral endplate<br />

2. Segmental lordosis L4-L5- angle upper<br />

endplate of L4 and lower endplate of L5<br />

3. Segmental lordosis L5-S1- angle upper<br />

endplate of L5 and the sacral endplate<br />

4. Global kyphosis- angle between the upper<br />

endplate of T4 and lower endplate of T12<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY<br />

TC<br />

PT<br />

LL<br />

PI<br />

SS


Results:<br />

global analysis after TDR at L5S1 or L4L5<br />

SAGITTAL BALANCE PARAMETERS<br />

60<br />

50<br />

Pre-op<br />

Post-op<br />

40<br />

30<br />

20<br />

10<br />

0<br />

Global<br />

Lordosis<br />

L4/L5 L5/S1 ST PT Kyphosis<br />

No statistical difference with regards to the overall :<br />

lordosis, ST, PT, kyphosis<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


Results: each group<br />

L4-L5<br />

PROSTHESIS AT L5/S1<br />

L5-S1<br />

60<br />

50<br />

P=0.61<br />

Pre-op<br />

Post-op<br />

40<br />

P=0.63<br />

P=0.24<br />

30<br />

20<br />

10<br />

0<br />

Global<br />

Lordosis<br />

P=0.05<br />

P=0.03<br />

L4/L5 L5/S1 ST PT Kyphosis<br />

No statistical difference with regards to the overall :<br />

lordosis, ST, PT, kyphosis<br />

P=0.57<br />

But significant difference in local lordosis ++++at L4L5<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


Results: each group<br />

PROSTHESIS AT L4/L5<br />

60<br />

50<br />

P=0.72<br />

Pre-op<br />

Post-op<br />

40<br />

30<br />

P=0.84<br />

P=0.39<br />

20<br />

10<br />

0<br />

Global<br />

Lordosis<br />

P=0.001<br />

P=0.053<br />

P=0.49<br />

L4/L5 L3L4 L5/S1 ST PT Kyphosis<br />

No statistical difference with regards to the overall :lordosis, ST, PT, kyphosis<br />

No significant difference in local lordosis at L5S1 p = 0,39<br />

But significant difference in local lordosis ++ at L3L4<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


Results<br />

Analyzis of each group: L4L5 and L5S1 prosthesis level:<br />

Segmental lordosis significantly increase<br />

at the level of prosthesis L4-L5 or L5-S1<br />

and decreased at above adjacent level<br />

But the overall lordosis did not change ++++<br />

No statistical difference in each group<br />

of overall lordosis, ST, PT, kyphosis<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY<br />

balance<br />

A1= 26° A1= 6°<br />

Standing position: balance of the spine


COMPARATIVE study:<br />

Maverick, CharitéIII, Prodisc<br />

(Tournier C, <strong>Le</strong> <strong>Huec</strong> <strong>JC</strong>, Eur Spine J, 2007)<br />

AT L5S1:<br />

location of MCR is very variable<br />

and difficult to calculate<br />

like in a healthy young population<br />

AT L4L5:<br />

location of MCR is posterior under superior L5 plateau<br />

ARE TDR more adapted to L4L5 than L5S1<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


Discussion<br />

TDA restore the local balance in between L4-L5-S1<br />

This is the inferior arch ++++<br />

TDA in between L4-L5-S1<br />

allows maintenance of motion and<br />

simultaneously allows the patient<br />

to adapt his own sagittal balance<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


TWO LEVELS TDR OR<br />

HYBRID<br />

Hybrid surgery: fusionL5S1 and disc arthroplasty L4L5<br />

OR<br />

two disc arthroplasties<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


Biomechanics of 2 levels charité in comparison to fusion plus<br />

single level disc placement combination<br />

spine J 2006, Grauer JN<br />

Finite element model analysis<br />

Cage +TDR / 2 level TDR<br />

The motion at L4L5 level were larger in cage+TDR as compared<br />

to 2 levelTDR<br />

But it is impossible to speculate if an increase in motion across a<br />

segment , as compared with the intact case, is more harmful than<br />

a decrease in motion<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


Hybrid testing of charité disc versus fusions<br />

spine, 2007 april, Penjabi M, Malcolmson G<br />

Cadaveric study Comparison:<br />

TDR, Fusion, TDR 2 levels, Fusion + TDR on top<br />

One and two levels fusion increased motions at proximal levels<br />

(22,9%)<br />

Two levels TDR showed some amount of variable effects at<br />

adjacent levels<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


One or two levels PRODISC versus fusions<br />

spine, 2007 may, Penjabi M, henderson G<br />

Cadaveric study Comparison:<br />

TDR, Fusion, TDR 2 levels, Fusion + TDR on top<br />

One and two levels TDR showed only small Adj <strong>Le</strong>vel Effect<br />

One and two levels fusions showed increased Adj <strong>Le</strong>vel Effect in<br />

all direction (7,8%, 35,3%)<br />

One level TDR + fusion showed small Adj <strong>Le</strong>vel Effect to One level<br />

fusion alone<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


BUT: clinical experience is different<br />

. Siepe CJ, Mayer HM, Heinz-<strong>Le</strong>isenheimer M, Korge A.<br />

Total lumbar disc replacement: different results<br />

for different levels. Spine. 2007; 32:782-90.<br />

showed a deterioration in postoperative results<br />

in both ODI and VAS for two-level TDA. the<br />

reduction in mean VAS back was 2.9 and<br />

reduction in mean ODI was 20%.<br />

TDA L4L5 better indication<br />

Two levels TDR isn’t as good as one level<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


Hybrid construct for two levels<br />

discopathies: a better compromise<br />

<strong>Le</strong> <strong>Huec</strong> <strong>JC</strong>, Meyrat R, Eur Spine J, 2009<br />

Group A:<br />

42 patients<br />

hybrid<br />

Group B: 28 patients double TDR<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


esults<br />

The hybrid construct provides same clinical outcomes<br />

as single level TDR in our experience<br />

Two levels TDR (Prodisc, Korge Siepe, Spine 07)<br />

have inferior results than single level<br />

This is probably in relation with the difficulty<br />

to ideally position the mean center of rotation on multilevels<br />

For hybrid The use of the BMP erases the problem of iliac crest pain<br />

In two levels TDR one third weren’t mobile at L5S1<br />

L4L5 TDR alone seems to be able to adapt spine balance<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


CONCLUSION<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


Take home message<br />

Pelvis shape and Spine shape are very important<br />

factors to analyse for the indication<br />

Pelvis shape and lumbar lordosis and incidence angle are highly<br />

correlated<br />

Type of spine , sacral slope and incidence angle determine good or bad<br />

indication for TDR<br />

ALIF L5S1 or TDR L5S1: : a lot of equivalence, difficult to show<br />

superiority<br />

TDR at L4L5 seems to be the best indication<br />

Two levels<br />

2 levels TDR hasn’ demonstrated superiority compare to fusion<br />

Hybrid construct (ALIF L5S1 and TDR L4L5) demonstrated better spine<br />

balance compare to two levels fusion<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY


Bordeaux :<br />

Saggital spine balance course<br />

September 24 – 25th 2010<br />

Objectives 1: analysis of spine and pelvis<br />

parameters<br />

Objectives 2: how to integrate balance<br />

parameters in your daily practice<br />

J-c.lehuec@u-bordeaux2.fr<br />

<strong>JC</strong> LE HUEC SPINE UNIT BORDEAUX UNIVERSITY

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