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PRODUCT SELECTION GUIDE – Innovative actives for personal care

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extraits de plantes des alpes suisses<br />

<strong>PRODUCT</strong> <strong>SELECTION</strong> <strong>GUIDE</strong> <strong>–</strong><br />

<strong>Innovative</strong> <strong>actives</strong> <strong>for</strong> <strong>personal</strong> <strong>care</strong> and beauty.<br />

plant extracts from the swiss alps


The World of PENTAPHARM<br />

Pentapharm Switzerland, founded in 1948,<br />

is recognised as a world leading company in the field<br />

of cosmetic active ingredients.<br />

The portfolio includes <strong>actives</strong> <strong>for</strong> all types of skin<br />

<strong>care</strong> applications complemented with selected<br />

products <strong>for</strong> hair <strong>care</strong>.<br />

Every product is provided with claim substantiation<br />

and an extended product dossier including safety<br />

aspects and in vivo as well in vitro studies.<br />

Through continuous commitment to research,<br />

Pentapharm is able to successfully introduce<br />

innovative products every year produced by<br />

means of peptide synthesis, extraction of natural<br />

substances and biotechnology.<br />

Pentapharm focuses on 4 core competencies:<br />

SYNTHETIC PEPTIDES: Thanks to its 25 years<br />

of pharmaceutical expertise in peptides and peptide<br />

mimetics, the developments of VIALOX ® ,<br />

SYN ® -COLL, SYN ® -AKE and SYN ® -TACKS have<br />

been possible in the cosmetics field;<br />

NATURAL SUBSTANCES: A wide field that<br />

is continuously being developed in the Cosmetic<br />

Division; the integration of ALPAFLOR ®<br />

into Pentapharm shows the commitment of<br />

PENTAPHARM in the development of further<br />

natural active ingredients.<br />

The ALP ® -ORGANIC range is Alpaflor ® ’s answer<br />

to all customers who want to produce organic/natural<br />

certified cosmetics or use plant extracts that<br />

are simply traceable. All ALP ® -ORGANIC active<br />

ingredients are certified by ECOCERT as raw<br />

material <strong>for</strong> Natural and Organic Cosmetics;<br />

BIOTECHNOLOGY: Research and development<br />

as well as production of high tech products;<br />

e.g. PEPHA ® -TIMP, highly purified SOD<br />

(Dismutin ® -BT) and ERYTHRULOSE produced<br />

via fermentation;<br />

SERVICE CENTER COSMETICS: The group<br />

ensures that any new cosmetic active ingredient<br />

is suitable <strong>for</strong> the most demanding cosmetic<br />

applications and provides important in<strong>for</strong>mation<br />

<strong>for</strong> <strong>for</strong>mulators. Customized product development<br />

as well as the development of DUAL VIAL SYSTEM<br />

<strong>for</strong>mulation are also done by this team.<br />

If your company is looking <strong>for</strong> the Qualitative<br />

Partner that has expertise in cosmetic research,<br />

product development and production following<br />

the highest standards required, Pentapharm<br />

should be your partner of choice.<br />

PENTAPHARM is represented on all continents<br />

by well known local distributors.<br />

For further in<strong>for</strong>mation please visit us at<br />

www.pentapharm.com.<br />

On August 29th, 2007 the ownership of Pentapharm<br />

was transferred to DSM Nutritional Products AG<br />

(headquarter Kaiseraugst/Switzerland), the world’s<br />

leading supplier of vitamins, carotenoids and other<br />

fine chemicals to the feed, food, pharmaceutical and<br />

<strong>personal</strong> <strong>care</strong> industries.


PENTAPHARM COSMETIC INGREDIENTS<br />

Anti-Aging:<br />

Skin Protection<br />

Profile of Ingredients<br />

Suppression of harmful environmental influences that lead to accelerated skin aging.<br />

Activity against reactive oxygen species, proteases, air pollutants (heavy metals,<br />

exhaust gases). For internal and external (photo aging) aged skin.<br />

Product Name (Code No.) Origin INCI Name (Active) Activity<br />

ABI COMPLEX AO<br />

ARTEMISIA AO<br />

BUDDLEJA AO<br />

COLHIBIN<br />

DISMUTIN ® -BT<br />

EDELWEISS EP<br />

EDELWEISS B.*<br />

ELHIBIN ®<br />

LIPOGARD*<br />

NECTAPURE PF*<br />

PEPHA ® -CTIVE<br />

PEPHA ® -PROTECT<br />

PEPHA ® -TIMP<br />

PREREGEN ®<br />

(930-01)<br />

(922-01)<br />

(920-01)<br />

(801057)<br />

(313-01)<br />

(900-13)<br />

(900-08)<br />

(301-02)<br />

(312-01)<br />

(911-04)<br />

(800545)<br />

(800464)<br />

(800420)<br />

(315-01)<br />

Plant<br />

Plant<br />

Plant<br />

Plant<br />

Biotech<br />

Plant<br />

Plant<br />

Plant/Synthetic<br />

Plant<br />

Biotech<br />

Plant<br />

Biotech<br />

Plant/Biotech<br />

Peucedanum Ostruthium<br />

Leaf Extract, Buddleja<br />

Davidii Extract, Artemisia<br />

Umbelli<strong>for</strong>mis Extract<br />

Artemisia Umbelli<strong>for</strong>mis<br />

Extract<br />

Buddleja Davidii Extract<br />

Hydrolyzed Rice Protein<br />

Superoxide Dismutase<br />

Leontopodium Alpinum<br />

Extract<br />

Glycine Soja (Soybean)<br />

Protein<br />

Squalane, Ubiquinone<br />

Buddleja Davidii<br />

Extract, Thymus Vulgaris<br />

(Thyme) Extract<br />

Algae Extract<br />

Citrullus Lanatus<br />

(Watermelon) Fruit Extract<br />

Human Oligopeptide-20<br />

Glycine Soja (Soybean)<br />

Protein, Oxido Reductases<br />

A complete anti-aging treatment with anti-oxidative,<br />

protective and repairing activity on the skin.<br />

Antioxidant and radical scavenging, anti-inflammatory,<br />

antimicrobial.<br />

DNA protective, antioxidant and radical scavenging, wound<br />

healing, antimicrobial.<br />

Plant-derived collagenase inhibitor, helps to protect skin<br />

from unscheduled collagen degradation. Direct benefit of<br />

maintaining the skin’s moisture content and elasticity.<br />

Highly purified yeast CuZnSOD, inactivates oxygen free<br />

radicals, minimizes <strong>for</strong>mation of inflammation, protects cell<br />

membranes.<br />

Antioxidant, radical scavenging and soothing properties.<br />

Purified soy bean peptide fraction, inhibits leukocyte and<br />

fibroblast elastase, prevents irritation and inflammation of<br />

skin, maintains skin elasticity, moisturizes the skin.<br />

Oil-soluble free radical scavenger, prevents lipid<br />

peroxidation.<br />

Against «city stress», increases the antioxidant defense by<br />

strengthening the endogenic system, exclusive detoxifying<br />

and moisturizing treatment, helps to keep radiance and vitality.<br />

Biotechnologically produced microalgae extract<br />

(Dunaliella salina) protects and stimulates mitochondria<br />

by increasing ATP levels. Improves skin radiance.<br />

Purified concentrate of compatible solutes based on watermelon<br />

fraction. Protects DNA. Improves skin’s<br />

protection system against sun rays.<br />

Biotechnologically derived, highly purified inhibitor of<br />

human matrix metallo proteinases (MMPs), identical to<br />

human TIMP-2, protects from UV-induced collagen<br />

breakdown, removes visible signs of photoaging.<br />

A unique complex with free radical neutralizing, elastase<br />

inhibiting properties and anti-ozone activity. Protects from<br />

pollution.<br />

Skin Energizing/<br />

Cell Revitalisation<br />

Profile of Ingredients<br />

Positive influence on fitness and energy of skin cells. Increase of cell proliferation<br />

and cell turnover rate. For healthy young looking skin.<br />

Product Name (Code No.) Origin INCI Name (Active) Activity<br />

Immucell ®<br />

Oxy 229-BT<br />

Pepha ® -ctive<br />

Pepha ® -nutrix*<br />

Placentol<br />

Revitalin ® -BT<br />

(302-01)<br />

(294-01)<br />

(800545)<br />

(800272)<br />

(165-04)<br />

(291-01)<br />

Biotech<br />

Biotech<br />

Biotech<br />

Milk<br />

Animal<br />

Biotech<br />

Glycoproteins<br />

Saccharomyces Lysate<br />

Algae Extract<br />

Colostrum Whey<br />

Placental Enzymes<br />

Glycoproteins<br />

Purified cytosolic fraction from yeast, increases cell turnover<br />

and cell proliferation, stimulates the immune<br />

system of the skin by increasing the phagocytotic activity.<br />

Activates and reactivates the tissue regeneration through<br />

a significant stimulation of cell respiration, has additional<br />

soothing activity.<br />

Biotechnologically produced microalgae extract<br />

(Dunaliella salina) protects and stimulates mitochondria<br />

by increasing ATP levels. Improves skin radiance.<br />

Youth prolonging complex of natural nutrition factors (oligopeptides,<br />

amino acids, vitamins, minerals), maintains<br />

and restores the skin›s youthful appearance, revitalizes<br />

the skin and promotes collagen <strong>for</strong>mation.<br />

Supports skin regeneration by increasing the metabolic<br />

rate and oyxgen consumption.<br />

Purified mitochondrial and cytoplasmic fraction from yeast,<br />

stimulates cell respiratory activity and cell-turnover, revitalizes<br />

cell metabolism, strengthens skin’s self-protection<br />

mechanism.<br />

*unpreserved<br />

ALPAFLOR ®<br />

Ecocert certified


Anti-Aging:<br />

Skin Regeneration &<br />

Functional Support<br />

Profile of Ingredients<br />

Positive interaction on cells and structural elements of the skin. Activation or induction<br />

of synthesis of molecules of the extracellular matrix. Strong effect on superficial wrinkles<br />

and fine lines.<br />

Product Name (Code No.) Origin INCI Name (Active) Activity<br />

ABI COMPLEX AO<br />

ImperatoRIA AO<br />

Pepha ® -Nutrix*<br />

PLANTAGO AO<br />

Preregen ®<br />

Regu ® -age<br />

Regu ® -STRETCH<br />

Syn ® -coll*<br />

SYN ® -TACKS*<br />

(930-01)<br />

(927-01)<br />

(800272)<br />

(924-01)<br />

(315-01)<br />

(800131)<br />

(801330)<br />

(800421)<br />

(801045)<br />

Plant<br />

Plant<br />

Milk<br />

Plant<br />

Plant/Biotech<br />

Plant/Biotech<br />

Plant/<br />

Synthetic<br />

Synthetic<br />

Synthetic<br />

Peucedanum Ostruthium<br />

Leaf Extract, Buddleja<br />

Davidii Extract, Artemisia<br />

Umbelli<strong>for</strong>mis Extract<br />

Peucedanum Ostruthium<br />

Leaf Extract<br />

Colostrum Whey<br />

Plantago Lanceolata<br />

Leaf Extract<br />

Glycine Soja (Soybean)<br />

Protein, Oxido Reductases<br />

Hydrolyzed Rice Bran<br />

Protein, Glycine Soja<br />

(Soybean) Protein,<br />

Oxido Reductases<br />

Panthenol, Marrubium<br />

Vulgare Extract, Palmitoyl<br />

Tripeptide-5<br />

Palmitoyl Tripeptide-5<br />

Palmitoyl Dipeptide-5<br />

Diamino butyroyl<br />

Hydroxythreonine,<br />

Palmitoyl Dipeptide-5<br />

Diaminohydroxybutyrate<br />

A complete anti-aging treatment with anti-oxidative,<br />

protective and repairing activity on the skin.<br />

Accelerates wound healing and skin’s revitalization.<br />

Youth prolonging complex of natural nutrition factors<br />

(oligopeptides, amino acids, vitamins, minerals), maintains<br />

and restores the skin’s youthful appearance, revitalizes<br />

the skin and promotes collagen <strong>for</strong>mation.<br />

Enhances collagen production, wound healing, antioxidant.<br />

A unique complex with free radical neutralizing, elastase<br />

inhibiting properties and anti-ozone activity. Protects from<br />

pollution.<br />

Anti-aging complex that reduces dark circles and puffiness<br />

around the eyes, prevents irritation and inflammation of<br />

the skin.<br />

An unique complex that protects the skin structure<br />

from stretch marks, and activates the repairing process by<br />

stimulating the synthesis of collagen and reducing<br />

the skin inflammation. Additionally the skin is moisturized<br />

and smoothed; the body appearance is restored.<br />

Synthetic tripeptide, boosts collagen synthesis<br />

via TGF-ß stimulation, removes any type of wrinkles.<br />

Stimulates significantly all relevant proteins of the Dermal-<br />

Epidermal Junction (DEJ), has outstanding activity on skin<br />

tone, elasticity and density.<br />

Anti-Wrinkle:<br />

Expression Line<br />

Refinement<br />

Profile of Ingredients<br />

Leveling off the skin and smoothing of expression lines by biochemical mechanisms such<br />

as relaxation of overactive facial muscles. Strong effect on deep wrinkles.<br />

Product Name (Code No.) Origin INCI Name (Active) Activity<br />

Syn ® -ake*<br />

Vialox ® powder*<br />

(800628)<br />

(099-12)<br />

Synthetic<br />

Synthetic<br />

Dipeptide Diaminobutyroyl<br />

Benzylamide Diacetate<br />

Pentapeptide-3<br />

Mimics the activity of Waglerin 1, a protein found in<br />

the venom of the Temple viper, excellent anti-wrinkle<br />

properties, inhibits nicotinic AChR, thus reduces muscle<br />

contractions.<br />

Topical alternative to injections, intensive anti-wrinkle<br />

<strong>care</strong>, especially fighting against expression lines.<br />

Inhibits muscle contractions as competitive antagonist<br />

at the AChR receptor.<br />

Tightening/<br />

Firming<br />

Profile of Ingredients<br />

Tightening of the skin and smoothing of wrinkles by biophysical mechanisms.<br />

Product Name (Code No.) Origin INCI Name (active) Activity<br />

PentA<strong>care</strong>-HP<br />

Penta<strong>care</strong>-NA<br />

Pepha ® -tight<br />

(305-02)<br />

(319-01)<br />

(800356)<br />

Plant/Animal<br />

Plant<br />

Biotech<br />

Ceratonia Siliqua Gum,<br />

Hydrolyzed Casein<br />

Hydrolyzed Wheat Gluten,<br />

Ceratonia Siliqua Gum<br />

Algae Extract, Pullulan<br />

Film <strong>for</strong>ming, strong tightening and anti-wrinkle activity.<br />

Skin tightener with instant feel, moisturizing, film-<strong>for</strong>ming.<br />

Based on biotechnologically derived microalgae<br />

(Nannochloropsis oculata), excellent immediate skin<br />

tightening effect, has in parallel a long term firming effect:<br />

protects the skin cells against oxidative stress and<br />

stimulates the <strong>for</strong>mation of collagen type l.<br />

*unpreserved ALPAFLOR ® Ecocert certified


Microcirculation<br />

Regulation<br />

Profile of Ingredients<br />

Positive influence on the skin microcirculation.<br />

Product Name (Code No.) Origin INCI Name (Active) Activity<br />

Regu ® -age<br />

Sambucus AO<br />

(800131)<br />

(925-01)<br />

Plant/Biotech<br />

Plant<br />

Hydrolyzed Rice Bran<br />

Protein, Soja (Soybean)<br />

Protein, Oxido Reductases,<br />

Glycine<br />

Sambucus Nigra Flower<br />

Extract<br />

Anti-aging complex that reduces dark circles and puffiness<br />

around the eyes, prevents irritation and inflammation of<br />

the skin.<br />

Reduces the biosynthesis of VEGF, anti-inflammatory,<br />

anti-oedemic.<br />

Moisturizing/<br />

Hydroregulation<br />

Profile of Ingredients<br />

Hydration of the skin by hygroscopic or occlusive effects or influencing endogenic<br />

biochemical pathways. For a perfect hydrated skin.<br />

Product Name (Code No.) Origin INCI Name (Active) Activity<br />

Collagen<br />

Hyaluronic Acid* (182-06)<br />

Hyaluronic Acid-BT* (295-03)<br />

HyaSOL-BT<br />

(296-04)<br />

Hydrolastan<br />

MALVA AO<br />

NeCTAPURE PF*<br />

Pentaglycan<br />

Pentavitin ® *<br />

Phytaluronate ®<br />

Sericin<br />

(150-01)<br />

(170-02)<br />

(928-01)<br />

(911-04)<br />

(181-01)<br />

(180-01)<br />

(298-01)<br />

(303-02)<br />

Animal<br />

Animal<br />

Biotech<br />

Biotech<br />

Animal<br />

Plant<br />

Plant<br />

Marine<br />

Plant<br />

Plant<br />

Silk<br />

Soluble Collagen<br />

Sodium Hyaluronate<br />

Sodium Hyaluronate<br />

Hydrolyzed Elastin<br />

Malva Sylvestris (Mallow)<br />

Flower Extract<br />

Buddleja Davidii<br />

Extract, Thymus Vulgaris<br />

(Thyme) Extract<br />

Glycosaminoglycans<br />

Saccharide Isomerate<br />

Ceratonia Siliqua Gum<br />

Sericin<br />

High potential to bind water, helps to promote skin<br />

hydration, accelerates wound healing.<br />

Binds tremendous amounts of moisture to skin, granting<br />

elasticity and suppleness.<br />

Hyasol BT is an aqueous solution of HYALURONIC-ACID BT.<br />

It binds tremendous amounts of moisture to skin and offers<br />

outstanding spreading and lubricating properties<br />

to your <strong>for</strong>mula.<br />

Protection of skin and hair, film-<strong>for</strong>ming.<br />

Soothing, anti-irritant, emollient, moisturizing, antiinflammatory.<br />

Against «city stress», increases the antioxidant defense by<br />

strengthening the endogenic system, exclusive detoxifying<br />

and moisturizing treatment, helps to keep radiance and vitality.<br />

Imparts lubricity to skin surface, has moisturizing and<br />

smoothing properties.<br />

Carbohydrate complex, increases water holding capacity<br />

of the stratum corneum, binds to keratin of the horny layer,<br />

reduces dryness and irritation caused by alpha hydroxy<br />

acids (AHAs).<br />

Moisturizing and skin smoothing properties, <strong>for</strong>ms a light,<br />

permeable, visco-elastic film, has a high compatibility to<br />

raw materials in cosmetic <strong>for</strong>mulations due to its neutral<br />

charging, increases water holding capacity.<br />

HMW sericin from silk, improves skin relief, smoothing<br />

and moisturizing activity, decreases TEWL, film-<strong>for</strong>ming,<br />

persists even after washing. Leads to a silky skin touch.<br />

Barrier<br />

Regulation &<br />

Functional<br />

Support<br />

Profile of Ingredients<br />

Regeneration of the epidermal lipid barrier (reduction of the transepidermal water loss) by<br />

replenishment of lipids or activation of lipid synthesis. For skin nourishing.<br />

Product Name (Code No.) Origin INCI Name (Active) Activity<br />

Cephalipin<br />

Cerasol*<br />

Fitobroside<br />

Lactomide<br />

SCUTELLARIA AO<br />

Stimu-tex ® *<br />

Stimu-tex ® As*<br />

(293-01)<br />

(321-01)<br />

(292-01)<br />

(309-01)<br />

(956-01)<br />

(290-01)<br />

(290-02)<br />

Plant<br />

Biotech<br />

Plant<br />

Milk/Biotech<br />

Plant<br />

Plant<br />

Plant<br />

Cephalins, Disodium<br />

Cocoamphodiacetate<br />

Hexyldecanol, Ceramide 3<br />

Triticum Vulgare (Wheat)<br />

Germ Extract<br />

Milk Lipids, Ceramide 3<br />

Scutellaria Alpina<br />

Flower/Leaf/Stem Extract<br />

Spent Grain Wax<br />

Spent Grain Wax,<br />

Butyrospermum Parkii<br />

(Shea Butter) Extract,<br />

Argania Spinosa Kernel Oil<br />

Cereal derived cephalin fraction, contributes to the regeneration<br />

of skin lipids, suitable <strong>for</strong> after shave and tooth<br />

paste <strong>for</strong>mulations due to its hemostatic properties.<br />

Solubilized bioengineered ceramides, leading to<br />

regeneration of the epidermal barrier.<br />

Reconstitutes intercellular lipid layers of the stratum corneum,<br />

reduces TEWL.<br />

Liposomal dispersion, compensates loss of lipids in<br />

permeability barrier, reduces TEWL.<br />

Beta-endorphin stimulating: «happiness inducing», lipid<br />

replenishing, anti-inflammatory, soothing, anti-oxidant,<br />

radical scavenging.<br />

Soothes dry and irritated skin, antipruritic and antiinflammatory<br />

activities, lipid replenishing, reduces TEWL.<br />

Soothes irritated skin, has strong histamine blocking,<br />

anti-itching and anti-inflammatory activities.


Sebum<br />

Regulation/<br />

Skin Flora<br />

Regulation<br />

Profile of Ingredients<br />

Positive influence on seborrheic and acne-prone skin and on skin flora.<br />

Product Name (Code No.) Origin INCI Name (Active) Activity<br />

ALP ® -SEBUM<br />

Hyssopus AO<br />

Regu ® -seb*<br />

THYMUS AO<br />

(953-01)<br />

(923-01)<br />

(331-01)<br />

(921-01)<br />

Plant<br />

Plant<br />

Plant<br />

Plant<br />

Epilobium Fleischeri Extract<br />

Hyssopus Officinalis<br />

Extract<br />

Argania Spinosa Kernel<br />

Extract, Serenoa Serrulata<br />

Fruit Extract, Sesamum<br />

Indicum (Sesame) Seed<br />

Extract<br />

Thymus Vulgaris<br />

(Thyme) Extract<br />

Outstanding sebum regulation capacity (inhibition of<br />

5a-reductase), reduces the size of pores and oily appearance<br />

of skin, anti-inflammatory (inhibition of IL-1 and IL-8).<br />

Antimicrobial and antiseptic, anti-inflammatory, antioxidant.<br />

Effective long term regulation and control of sebum, based<br />

on 5a-reductase inhibition.<br />

Anti-microbial, anti-bacterial, anti-inflammatory.<br />

Soothing/<br />

Anti-Irritation/<br />

Anti-Inflammatory<br />

Profile of Ingredients<br />

Positive influence on irritated and sensitive skin.<br />

Product Name (Code No.) Origin INCI Name (Active) Activity<br />

Calendula AO<br />

Eashave<br />

Echinacea AO<br />

Edelweiss EP<br />

Edelweiss B.*<br />

Elhibin ®<br />

HYPERICUM B.<br />

Iricalmin<br />

LINUM AO<br />

MALVA AO<br />

Marrubium AO<br />

Pentavitin ® *<br />

Sambucus AO<br />

Sericin<br />

SeTAKOL ®<br />

SeTAKOL ® Powder*<br />

Stimu-tex ® *<br />

Stimu-tex ® As*<br />

(903-03)<br />

(316-01)<br />

(902-05)<br />

(900-13)<br />

(900-08)<br />

(301-02)<br />

(904-03)<br />

(316-02)<br />

(929-01)<br />

(928-01)<br />

(926-01)<br />

(180-01)<br />

(925-01)<br />

(303-02)<br />

(320-01)<br />

(333-01)<br />

(290-01)<br />

(290-02)<br />

Plant<br />

Plant/Biotech<br />

Plant<br />

Plant<br />

Plant<br />

Plant<br />

Plant/Biotech<br />

Plant<br />

Plant<br />

Plant<br />

Plant<br />

Plant<br />

Silk<br />

Silk<br />

Plant<br />

Plant<br />

Calendula Officinalis Flower<br />

Extract<br />

Triticum Vulgare<br />

(Wheat) Germ Extract,<br />

Saccharomyces Cerevisiae<br />

Extract, Sodium<br />

Hyaluronate<br />

Echinacea Purpurea Extract<br />

Leontopodium Alpinum<br />

Extract<br />

Glycine Soja (Soybean)<br />

Protein<br />

Hypericum Per<strong>for</strong>atum<br />

Extract<br />

Triticum Vulgare<br />

(Wheat) Germ Extract,<br />

Saccharomyces Cerevisiae<br />

Extract, Sodium<br />

Hyaluronate<br />

Linum Alpinum<br />

Flower/Leaf/Stem Extract<br />

Malva Sylvestris (Mallow)<br />

Flower Extract<br />

Marrubium Vulgare Extract<br />

Saccharide Isomerate<br />

Sambucus Nigra Flower<br />

Extract<br />

Sericin<br />

Hydrolyzed Sericin<br />

Spent Grain Wax<br />

Spent Grain Wax,<br />

Butyrospermum Parkii<br />

(Shea Butter) Extract,<br />

Argania Spinosa Kernel Oil<br />

Soothing and healing, antiseptic.<br />

Eases shaving, anti-irritant, sebum-replenishing and moisturizing<br />

properties.<br />

Protecting and antiseptic, especially <strong>for</strong> stressed and tired<br />

skin.<br />

Antioxidant, radical scavenging and soothing properties.<br />

Purified soy bean peptide fraction, inhibits leukocyte and<br />

fibroblast elastase, prevents irritation and inflammation of<br />

skin, maintains skin elasticity, moisturizes the skin.<br />

Anti-inflammatory: inhibits COX-1 and COX-2 as well as IL-<br />

1 and PGE2, soothing and healing.<br />

Soothes irritated skin caused by UV and depilation, has<br />

anti-irritant, sebum-replenishing, moisturizing and cooling<br />

properties.<br />

Anti-inflammatory, anti-oxidant, soothing, calming.<br />

Soothing, anti-irritant, emollient, moisturizing, antiinflammatory.<br />

Anti-histaminic, anti-inflammatory, wound healing,<br />

antimicrobial.<br />

Carbohydrate complex, increases water holding capacity<br />

of the stratum corneum, binds to keratin of the horny layer,<br />

reduces dryness and irritation caused by alpha hydroxy<br />

acids (AHAs).<br />

Reduces the biosynthesis of VEGF, anti-inflammatory, antioedemic.<br />

HMW sericin from silk, improves skin relief, smoothing<br />

and moisturizing activity, decreases TEWL, film-<strong>for</strong>ming,<br />

persists even after washing. Leads to a silky skin touch.<br />

Gives new condition to stressed hair, <strong>for</strong>mes a film that<br />

protects and strenghtens scalp and hair.<br />

Soothes dry and irritated skin, antipruritic and antiinflammatory<br />

activities, lipid replenishing, reduces TEWL.<br />

Soothes irritated skin, has strong histamine blocking,<br />

anti-itching and anti-inflammatory activities.<br />

*unpreserved ALPAFLOR ® Ecocert certified


Slimming/<br />

Body Shaping<br />

Profile of Ingredients<br />

Positive influence on cellulite and on subcutaneous adipose tissue.<br />

For a perfect body shiloutte.<br />

Product Name (Code No.) Origin INCI Name (Active) Activity<br />

Regu ® -shape<br />

Regu ® -slim*<br />

(800134)<br />

(334-01)<br />

Plant<br />

Plant/Synthetic<br />

Isomerized Linoleic<br />

Acid, Lecithin, Glycerin,<br />

Polysorbate 80<br />

Maltodextrin, Caffeine,<br />

Paullinia Cupana Seed<br />

Extract, Carnitine, Microcrystalline<br />

Cellulose,<br />

Cysteic Acid, Pantetheine<br />

Sulfonate<br />

Nano-emulsion based on conjugated linoleic acid,<br />

prevents lipid uptake into adipocytes, stimulates the<br />

breakdown of lipids in adipocytes.<br />

Improves body aesthetics by reducing sub-cutaneous lipids,<br />

smoothing the skin’s appearance, firming tissues and<br />

restoring the body’s youthful look.<br />

Skin Lightening/<br />

Anti-Age Spots<br />

Profile of Ingredients<br />

Lightening of the skin by bleaching of endogeneous pigmentation or inhibition<br />

of melanogenesis. Even out of skin tone.<br />

Product Name (Code No.) Origin INCI Name (Active) Activity<br />

Alpha-Arbutin*<br />

(336-01)<br />

Synthetic<br />

Alpha-Arbutin<br />

Effective and fast skin lightener, minimizes age spots.<br />

Gigawhite*<br />

Melawhite ®<br />

Melfade ® -J<br />

(910-02)<br />

(282-01)<br />

(308-04)<br />

Plant<br />

Animal<br />

Plant/Synthetic<br />

Malva Sylvestris (Mallow)<br />

Extract, Mentha Piperita<br />

(Peppermint) Leaf Extract,<br />

Primula Veris Extract,<br />

Alchemilla Vulgaris Extract,<br />

Veronica Officinalis Extract,<br />

Melissa Officinalis Leaf<br />

Extract, Achillea Millefolium<br />

Extract<br />

Leukocyte Extract<br />

Arctostaphylos Uva-Ursi<br />

Leaf Extract, Magnesium<br />

Ascorbyl Phosphate<br />

Skin lightener with anti-age spot activity.<br />

Tyrosinase inhibitor; minimizes <strong>for</strong>mation of melanin,<br />

freckles, liver spots, age-pigmentation.<br />

Tyrosinase inhibitor, suitable <strong>for</strong> quasi drug <strong>for</strong>mulations.<br />

Skin Tanning<br />

Profile of Ingredients<br />

Systems <strong>for</strong>ming colored dyes by interaction with skin surface.<br />

Product Name (Code No.) Origin INCI Name (Active) Activity<br />

ERYTHRULOSE*<br />

(307-01) Biotech Erythrulose<br />

Biotechnologically derived to give a new dimension<br />

<strong>for</strong> your self tanning products. Leads to a deep, even<br />

and natural long lasting tan without streaks, avoids<br />

skin dryness. Use in combination with DHA<br />

is recommended (global patent by Pentapharm).<br />

Hair Care/<br />

Scalp Care<br />

Profile of Ingredients<br />

For hair and scalp treatment.<br />

Product Name (Code No.) Origin INCI Name (Active) Activity<br />

Hydrolastan<br />

Sericin<br />

SeTAKOL ®<br />

SeTAKOL ® Powder*<br />

Stimu-tex ® AS*<br />

(170-02)<br />

(303-02)<br />

(320-01)<br />

(333-01)<br />

(290-02)<br />

Animal<br />

Silk<br />

Silk<br />

Plant<br />

Hydrolyzed Elastin<br />

Sericin<br />

Hydrolyzed Sericin<br />

Spent Grain Wax,<br />

Butyrospermum Parkii<br />

(Shea Butter) Extract,<br />

Argania Spinosa Kernel Oil<br />

Protection of skin and hair, film-<strong>for</strong>ming.<br />

HMW sericin from silk, improves skin relief, smoothing<br />

and moisturizing activity, decreases TEWL, film-<strong>for</strong>ming,<br />

persists even after washing. Leads to a silky skin touch.<br />

Gives new condition to stressed hair, <strong>for</strong>mes a film that<br />

protects and strenghtens scalp and hair.<br />

Soothes irritated skin, has strong histamine blocking,<br />

anti-itching and anti-inflammatory activities.<br />

*unpreserved ALPAFLOR ®


PENTAPHARM<br />

COSMETIC<br />

INGREDIENTS<br />

*unpreserved<br />

ALPAFLOR ®<br />

Ecocert certified<br />

Anti-Aging:<br />

Skin Protection<br />

Skin Energizing/<br />

Cell Revitalisation<br />

Anti-Aging:<br />

Skin Regeneration &<br />

Functional Support<br />

Anti-Wrinkle:<br />

Expression Line<br />

Refinement<br />

Tightening/Firming<br />

Microcirculation<br />

Regulation<br />

Moisturizing/<br />

Hydroregulation<br />

Barrier Regulation &<br />

Functional Support<br />

Sebum Regulation/<br />

Skin Flora Regulation<br />

Soothing/<br />

Anti-Irritation/<br />

Anti-Inflammatory<br />

Slimming/<br />

Body Shaping<br />

Skin Ligthening/<br />

Anti-Age Spots<br />

Skin Tanning<br />

Hair Care<br />

gruner brenneisen communications 6004<br />

ABI-COMPLEX AO (930-01)<br />

ALP ® -SEBUM (953-01)<br />

ALPHA-ARBUTIN* (336-01)<br />

ARTEMISIA AO (922-01)<br />

BUDDLEJA AO (920-01)<br />

CALENDULA AO (903-03)<br />

CEPHALIPIN (293-01)<br />

CERASOL* (321-01)<br />

COLHIBIN (801057)<br />

COLLAGEN (150-01)<br />

DISMUTIN ® -BT (313-01)<br />

EASHAVE (316-01)<br />

ECHINACEA AO (902-05)<br />

EDELWEISS EP (900-13)<br />

ELHIBIN ® (301-02)<br />

ERYTHRULOSE* (307-01)<br />

FITOBROSIDE (292-01)<br />

GIGAWHITE* (910-02)<br />

HYALURONIC ACID-BT* (295-03)<br />

Hyasol-BT (296-04)<br />

HYDROLASTAN (170-02)<br />

HYPERICUM B. (904-03)<br />

HYSSOPUS AO (923-01)<br />

IMMUCELL ® (302-01)<br />

IMPERATORIA AO (927-01)<br />

IRICALMIN (316-02)<br />

LACTOMIDE (309-01)<br />

LINUM AO (929-01)<br />

LIPOGARD* (312-01)<br />

MALVA AO (928-01)<br />

MARRUBIUM AO (926-01)<br />

MELAWHITE ® (282-01)<br />

MELFADE ® -J (308-04)<br />

NECTAPURE PF* (911-04)<br />

OXY 229-BT (294-01)<br />

PENTACARE-HP (305-02)<br />

PENTACARE-NA (319-01)<br />

PENTAGLYCAN (181-01)<br />

PENTAVITIN ® * (180-01)<br />

PEPHA ® -CTIVE (800545)<br />

PEPHA ® -NUTRIX* (800272)<br />

PEPHA ® -PROTECT (800464)<br />

PEPHA ® -TIGHT (800356)<br />

PEPHA ® -TIMP (800420)<br />

PHYTALURONATE ® (298-01)<br />

PLANTAGO AO (924-01)<br />

PREREGEN ® (315-01)<br />

REGU ® -AGE (800131)<br />

REGU ® -SEB* (331-01)<br />

REGU ® -SHAPE (800134)<br />

REGU ® -SLIM (334-01)<br />

REGU ® -STRETCH (801330)<br />

REVITALIN ® -BT (291-01)<br />

SAMBUCUS AO (925-01)<br />

SCUTELLARIA AO (956-01)<br />

SERICIN (303-02)<br />

SETAKOL ® (320-01)<br />

SETAKOL ® POWDER* (333-01)<br />

STIMU-TEX ® * (290-01)<br />

STIMU-TEX ® AS* (290-02)<br />

SYN ® -AKE* (800628)<br />

SYN ® -COLL* (800421)<br />

SYN ® -TACKS* (801045)<br />

THYMUS AO (921-01)<br />

VIALOX ® POWDER* (099-12)<br />

Registered as DSM Nutritional Products Ltd Branch Pentapharm<br />

Engelgasse 109, P. O. Box, CH-4002 Basel/Switzerland, Phone: +41 61-706 48 48, Fax: +41 61-319 96 19, www.pentapharm.com

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