FERRONYL® IRON

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Physical & Chemical Properties Product Description Ferronyl iron powder is elemental iron manufactured by the chemical decomposition of iron pentacarbonyl. The resulting iron particles are small, uniform particles of high purity with only traces of carbon, oxygen and nitrogen. Chemical Description: Elemental Iron CAS Registry Number: 7439-89-6 CAS Registry Name: Iron Chemical Formula: Fe Synonyms: Carbonyl iron, carbonyl iron powder (CIP) Iron Content With greater than 98% iron, Ferronyl iron has a much higher iron level than ferrous salts, such as ferrous gluconate, ferrous sulfate and ferrous fumarate (Table 1). As a result, substantially less Ferronyl iron is required to reach the same unit dose than a ferrous salt, resulting in lower tablet weight. This makes Ferronyl iron well suited for multivitamin applications with high active levels as Ferronyl iron can reduce tablet weight. Table 1. Less Ferronyl iron is required to reach same unit dose compared to other iron sources. Ferronyl Iron (Fe) Ferrous Gluconate (C 12 H 22 O 19 Fe) Ferrous Fumarate (C 4 H 2 FeO 4 ) Ferrous Sulfate (FeSO 4 ) % Iron 98 12 32 36 Molecular Weight 56 446 170 152 Amount of Iron Supplement needed to meet US RDA* 18.4 mg 150.0 mg 54.4 mg 50.0 mg *RDA (Recommended Daily Allowance) for Adults is 18 mg/day. 4
Physical & Chemical Properties Particle Morphology Ferronyl carbonyl iron powder (CIP) is a grey powder. When examined under a scanning electron microscope (SEM), Ferronyl iron particles are highly spherical (Figure 1). The spherical particle morphology provides for excellent flow during manufacturing. Figure 1. Ferronyl iron particles are spherical providing good flow properties. Particle Size and Particle Size Distribution Ferronyl carbonyl iron has a narrow particle size distribution (Figure 2). The typical average particle size is about 7 to 9 microns which is smaller than the 10-100 microns of other forms of elemental iron (e.g., reduced, electrolytic and atomized). This small particle size contributes to its high bioavailability. With a narrow particle size distribution, Ferronyl iron does not require additional processing prior to formulation. Other iron sources can have wide particle size distributions and, thus, must be sieved, milled or ground prior to use which adds time and cost to the manufacturing process. Figure 2. Ferronyl carbonyl iron has a narrow particle size distribution and small particle size. Typical Average Particle Size = 7-9 µm 10 Volume % 0.1 1.0 10.0 100.0 1000.0 Particle Diameter (µm) 0 A Better Choice 5
Page 1 and 2: FERRONYL® IRON Dietary Iron Supple
Page 3: Introduction Iron deficiency contin
Page 7 and 8: Bioavailability The amount of iron
Page 9 and 10: Applications Liquid Suspensions For
Page 11 and 12: Safety & Toxicity Summary Animal To
Page 13 and 14: Safety & Toxicity Summary Plasma ir
Page 15 and 16: Summary Each year accidental iron o

FERRONYL® IRON

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