FERRONYL® IRON

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Contents Introduction 3 Physical and Chemical Properties 4-6 Product Description Iron Content Particle Morphology Particle Size and Particle Size Distribution Stability Bioavailability 7 Applications 8-9 Tablets Liquid Suspensions Safety and Toxicity Summary 10-13 Poison Control Statistics Animal Toxicity Studies Regulatory 14 Summary 15 References 15
Introduction Iron deficiency continues to be a concern around the world, especially in women and children, often resulting in anemia. One approach to prevent iron deficiency is supplementation of food, vitamins and nutritional products. In formulating an iron supplement, one must consider bioavailability, toxicity, side effects, iron content, stability, taste and ease of formulation when selecting an iron source. Ferronyl® iron is an ideal source of essentially pure iron with low toxicity, minimal metallic taste and excellent bioavailability. Thus, it is the better choice for iron supplementation. Ferronyl iron powder is elemental iron (Fe) with high (> 98%) iron content. High iron content results in lower use levels to achieve same daily intake levels compared to ferrous (Fe 2+ ) salts (e.g., ferrous sulfate, ferrous fumarate, or ferrous gluconate). This is important in multivitamin formulations where smaller tablets are preferred for consumer compliance, but often difficult to achieve with the large number of actives in a formulation. Benefits of Ferronyl Iron Powder ● Low Use Levels In addition to the high iron content, a key physical property of Ferronyl iron is its fine spherical particle size that results in higher human bioavailability than other elemental iron forms. Each year accidental iron overdose accounts for a significant number of emergency room visits and too many childhood deaths. Thus, one must consider toxicity when selecting an iron source for a supplement product. Ferronyl iron is far less toxic than soluble iron salts, it causes fewer side effects, and the slow absorption from the GI tract provides time for clinical intervention in the event of accidental overdose. ● ● ● ● ● Low Toxicity Excellent Bioavailability Highly Resistant to Oxidation Easy to Formulate Generally Recognized as Safe (GRAS) With its low use level, excellent bioavailability and low toxicity, Ferronyl iron is a better choice for iron supplementation, of: ● ● ● Multivitamin and iron supplement tablets; Chewable vitamin tablets; and Liquid suspensions. A Better Choice 3
Page 1: FERRONYL® IRON Dietary Iron Supple
Page 5 and 6: Physical & Chemical Properties Part
Page 7 and 8: Bioavailability The amount of iron
Page 9 and 10: Applications Liquid Suspensions For
Page 11 and 12: Safety & Toxicity Summary Animal To
Page 13 and 14: Safety & Toxicity Summary Plasma ir
Page 15 and 16: Summary Each year accidental iron o

FERRONYL® IRON

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