DNA Microarray Image Analysis - University of Illinois at Urbana ...
DNA Microarray Image Analysis - University of Illinois at Urbana ...
DNA Microarray Image Analysis - University of Illinois at Urbana ...
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<strong>DNA</strong> <strong>Microarray</strong> <strong>Image</strong> <strong>Analysis</strong><br />
• The goal <strong>of</strong> microarray image analysis steps is to extract<br />
intensity descriptors from each spot th<strong>at</strong> represent gene<br />
expression levels and input fe<strong>at</strong>ures for further analysis.<br />
Biological conclusions are then drawn based on the results from<br />
d<strong>at</strong>a mining and st<strong>at</strong>istical analysis <strong>of</strong> all extracted fe<strong>at</strong>ures.<br />
• Components <strong>of</strong> <strong>DNA</strong> <strong>Microarray</strong> <strong>Analysis</strong><br />
— Grid Alignment Problem<br />
— Foreground Separ<strong>at</strong>ion<br />
— Quality Assurance<br />
— Quantific<strong>at</strong>ion<br />
— Normaliz<strong>at</strong>ion<br />
• D<strong>at</strong>a management - Minimal Inform<strong>at</strong>ion About <strong>Microarray</strong><br />
Experiments (MIAME) standard<br />
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