Physiology and Pathophysiology of Neuromuscular Transmission
Physiology and Pathophysiology of Neuromuscular Transmission
Physiology and Pathophysiology of Neuromuscular Transmission
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NMJ size <strong>and</strong> muscle mibre diameter are correlated<br />
Specific quantal content (m/µm 2 ) is constant<br />
A<br />
B<br />
100<br />
80<br />
1<br />
60<br />
40<br />
-2<br />
) mµ<br />
m/a<br />
(µm -2 ) 0.1<br />
%Occupancy<br />
% Occupancy<br />
20<br />
0<br />
sub super<br />
m/a (<br />
0.01<br />
sub-sub sub-super super-super<br />
Costanzo et al.(1999) J Physiol 521:365-74<br />
Species<br />
Quantal content<br />
Frog<br />
Rat<br />
Frog 200<br />
Rat, mouse 50-75<br />
Man 20-30<br />
Man<br />
26