Physiology and Pathophysiology of Neuromuscular Transmission

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Binomial statistics are a better predictor or response variability when p>0.1 p=0.044 p=0.49 Problems - Non-Poisson conditions - MEPP variance - Non-linear summation 20
The Normal (Gaussian) Distribution y = exp(!(x ! µ) 2 / 2" 2 ) / (" 2# ) y (!x 2 ) # % exp $ & 2" 0.25 y = 5 0.5 2' (µ = 0; σ =0.5) x n + P(x) = " exp(!m) mx .- k =1 x! ,- 1 % !( x ! kx ) 2 (. 2#k$ 2 ' 0 & 2k$ 2 * )/ 0 10 ' exp (! 3) " 3 x y 15 % ' & ( 1 '! ( x ! 1.1k) 2 ( % ' exp # x! $ 0.2 2)k # % 2k0.2 2 $ & & ( ( = * % & # # $ $ k = 1 m=3 quanta σ= 0.2 mv x =1.1mv 21
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Physiology and Pathophysiology of Neuromuscular Transmission

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