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Physiology and Pathophysiology of Neuromuscular Transmission

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EPP’s<br />

(muscle action potential blocked)<br />

EPP’s in low Ca/high Mg<br />

Mg 2+<br />

Ca 2+<br />

5 mV<br />

10.00 ms<br />

5 mV<br />

10.00 ms<br />

Binomial model:<br />

Let:<br />

n=3<br />

p= 0.17<br />

(q=1-p)<br />

m=n.p<br />

P(0) = ?<br />

P(1) = ?<br />

P(2) = ?<br />

P(3) = ?<br />

14

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