dr.sc. Zvonimir Koporc - Odjel za biotehnologiju - SveuÄiliÅ¡te u Rijeci
dr.sc. Zvonimir Koporc - Odjel za biotehnologiju - SveuÄiliÅ¡te u Rijeci
dr.sc. Zvonimir Koporc - Odjel za biotehnologiju - SveuÄiliÅ¡te u Rijeci
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
ŽIVOTOPIS<br />
Ime i a<strong>dr</strong>esa<br />
Osobni podatci<br />
Obrazovanje<br />
Dr.<strong>sc</strong>. <strong>Zvonimir</strong> <strong>Koporc</strong>, znanstveni suradnik<br />
Sveučilište u <strong>Rijeci</strong><br />
<strong>Odjel</strong> <strong>za</strong> <strong>biotehnologiju</strong><br />
S. Krautzeka b.b.<br />
51000 Rijeka, Hrvatska<br />
e-mail: zkoporc@biotech.uniri.hr<br />
Datum roĎenja: 30.03.1972.<br />
Mjesto roĎenja: Zagreb, Hrvatska<br />
2006 - nostrifikacija Agencije <strong>za</strong> znanost visoko obrazovanje RH<br />
(KL: UP/I *-602-06/06-02/0944//UR.BR.:355-05-06-04): doktor<br />
prirodnih znanosti polje kemija (<strong>dr</strong>.<strong>sc</strong>.)<br />
2006 - promocija Dr.rer.nat. (<strong>dr</strong>.<strong>sc</strong>.) TU- Beč, Republika Austrija<br />
Naslov doktorske dizertacije: “Use of mobilized peripheral blood<br />
stem cells for the induction of mixed chimerism and tolerance”<br />
1999 - EU-AT titula “Dipl.Ing.” BMWV-GZ 53.011/63-I/D/3/99<br />
1999 - promocija dipl.ing. prehrambene tehnologije i biotehnologije,<br />
Prehrambeno biotehnološki fakultet, Sveučilište u Zagrebu<br />
(diplomski rad u suradnji s BOKU-Beč), Naslov diplomskog rada:<br />
“Enzimska sinte<strong>za</strong> ksilitola”<br />
Članstvo<br />
Nagrade<br />
Österreichi<strong>sc</strong>he Gesell<strong>sc</strong>haft für Transplantation, Transfusion und<br />
Genetik<br />
Rektorova nagrada Sveučilišta u Zagrebu <strong>za</strong> najbolji studentski<br />
rad pod naslovom: „Biodegradacija sirove nafte“ šk. god.<br />
1995/1996<br />
Rektorova nagrada Sveučilišta u Zagrebu <strong>za</strong> najbolji studentski<br />
Životopis Dr. Sc. <strong>Zvonimir</strong> <strong>Koporc</strong> 1
Glavni istraživački interesi<br />
rad pod naslovom: „Enzimska sinte<strong>za</strong> ksilitola“ šk. god.<br />
1996/1997<br />
Nagrada “Austrotransplant-Biotest-Preis BIOTEST” godine 2003<br />
Nagrada <strong>za</strong> najbolji znanstveni poster na American Transplant<br />
Congress, Boston MA,USA 2004<br />
Nagrada “Young Investigator Travel Award” <strong>za</strong> “Basic Science<br />
Symposium of The Transplantation Society 2003”, Keystone,<br />
Colorado, USA<br />
Znanstveno i radno iskustvo:<br />
eksperimentalna transplantacijska imunologija, matične stanice<br />
2008-danas znanstveni evaluator <strong>za</strong> FP7-Marie Curie program, EUROPEAN<br />
COMMISSION<br />
2009-danas znanstveni suradnik <strong>Odjel</strong> <strong>za</strong> <strong>biotehnologiju</strong>, Sveučilište u <strong>Rijeci</strong><br />
2008-2009 znanstvenik povratnik – Institut RuĎer Bošković, Zavod <strong>za</strong> Molekularnu<br />
Medicinu<br />
2002-2006 znanstveni suradnik (“Wiss. mitarbeiter”): Allgemeine Krankenhaus<br />
(AKH), Beč- Austrija/EU, Klini<strong>sc</strong>he Abteilung für Transplantation,<br />
Transplant Labor, znanstveni tim A.O. Univ. Prof. Dr.Thomas Wekerle /<br />
mentorstvo Univ.Prof. Peter. C. Kubicek TU -Beč, Austrija, EU<br />
Dizertacija: Use of mobilized peripheral blood stem cells for the induction<br />
of mixed chimerism and tolerance<br />
2000-2001 znanstveni suradnik (“Wiss. mitarbeiter”): Allgemeine Krankenhaus<br />
(AKH), Beč- Austrija/EU, Institut für Pathophysiologie, znanstveni tim Univ.<br />
Prof. Dr. Jürg Graf /Ao. Univ. Prof. Dr. Renate Fuchs<br />
Projekt: Comparative analysis of the mechanism of uncoating of three<br />
different picornaviruses<br />
1999-2000 znanstveni suradnik (“Wiss. Mitarbeiter”): TU (Techni<strong>sc</strong>he Universität<br />
Wien) - Institut <strong>za</strong> kemijsko inžinjerstvo (Institute of Chemical Engineering)<br />
znanstveni tim Eur.-Ing.DI.Dr. Richard Gapes<br />
Projekt 1: Aceton Butanol Fermentation<br />
Project 2: Proizvodnja Biodizela (Production of Biodisel)<br />
Životopis Dr. Sc. <strong>Zvonimir</strong> <strong>Koporc</strong> 2
9/1996-5/1997<br />
diplomski rad: Enzymatical synthesis of xylitol<br />
BOKU (Universität für Bodenkultur Wien), Beč, Austrija/EU, Institut<br />
Prehrambene tehnologije i Biotehnologije (Institut für<br />
Lebensmitteltehnologie und Biotechnologie) znanstveni tim<br />
Univ.Prof.Dr.Klaus D. Kulbe<br />
Publikacije:<br />
1. Blaha P, Bigen<strong>za</strong>hn S, <strong>Koporc</strong> Z, Schmid M, Langer F, Selzer E,<br />
Bergmeister H, Wrba F, Kurtz J, Kiss C, Roth E, Muehlbacher F, Sykes M, Wekerle T:<br />
The influence of immunosuppressive <strong>dr</strong>ugs on tolerance induction through bone marrow<br />
transplantation with costimulation blockade. Blood 101: 2886-2893, 2003<br />
2. Wekerle T, Blaha P, <strong>Koporc</strong> Z, Bigen<strong>za</strong>hn S, Pu<strong>sc</strong>h M, Muehlbacher F:<br />
Mechanisms of tolerance induction through the transplantation of donor hematopoietic<br />
stem cells: central versus peripheral. Transplantation 75: 21S-25S, 2003<br />
3. <strong>Koporc</strong> Z, Pree I, Bigen<strong>za</strong>hn S, Blaha P, Nierlich P, Fariborz E, Sykes M,<br />
Muehlbacher F, Wekerle T: Murine Mobilized Peripheral Blood Stem Cells Have a Lower<br />
Capacity than Bone Marrow to Induce Mixed Chimerism and Tolerance, American<br />
Journal of Transplantation 8: 2025-2036, 2008<br />
4. Blaha P, Bigen<strong>za</strong>hn S, <strong>Koporc</strong> Z, Sykes M, Muehlbacher F, Wekerle T:<br />
Short-term immunosuppression facilitates induction of mixed chimerism and tolerance<br />
after BMT without cytoreductive conditioning. Transplantation 80: 237-43, 2005<br />
5. Bigen<strong>za</strong>hn S, Blaha P, <strong>Koporc</strong> Z, Pree I, Selzer E, Bergmeister H, Wrba<br />
F, Heusser C, Wagner K, Muehlbacher F, Wekerle T: The role of non-deletional<br />
tolerance mechanisms in a murine model of mixed chimerism with costimulation<br />
blockade. American Journal of Transplantation 5: 1237-1247, 2005<br />
6. <strong>Koporc</strong> Z, Bigen<strong>za</strong>hn S, Blaha P, Fariborz E, Selzer E, Sykes M,<br />
Muehlbacher F, Wekerle T: Induction of Mixed Chimerism through Transplantation of<br />
CD45-Congenic Mobilized Peripheral Blood Stem Cells after Nonmyeloablative<br />
Irradiation. Biology of Blood and Marrow Transplantation 12: 284-292 , 2006<br />
7. Pree I, Bigen<strong>za</strong>hn S, Fuchs D, <strong>Koporc</strong> Z, Nierlich P, Winkler C,<br />
Brandacher G, Sykes M, Muehlbacher F, Langer F, Wekerle T: CTLA4Ig PROMOTES<br />
THE INDUCTION OF HEMATOPOIETIC CHIMERISM AND TOLERANCE<br />
INDEPENDENTLY OF INDOLEAMINE-2,3-DIOXYGENASE (IDO). Transplantation<br />
83(5):663-,2007<br />
Oralne prezentacije, posteri i sažetci:<br />
1. <strong>Koporc</strong> Z, Blaha P, Bigen<strong>za</strong>hn S, Muehlbacher F, Sykes M, Wekerle T:<br />
Use of mobilized peripheral blood stem cells for the induction of mixed chimerism. Proc.<br />
Basic Sciences Symposium 2003 of The Transplantation Society 2003<br />
2. <strong>Koporc</strong> Z, Blaha P, Bigen<strong>za</strong>hn S, Muehlbacher F, Sykes M, Wekerle T:<br />
Use of mobilized peripheral blood stem cells for the induction of mixed chimerism and<br />
tolerance. European Surgery Acta Chirurgica Austrianica 35 : 12 , 2003<br />
3. Bigen<strong>za</strong>hn S, Blaha P, <strong>Koporc</strong> Z, Schmid M, Selzer E, Bergmeister H,<br />
Heusser C, Wagner K, Mühlbacher F, Wekerle T: : Influence of an anti-CD25 mAb on<br />
tolerance induction through BMT plus costimulation blockade. European Surgery Acta<br />
Životopis Dr. Sc. <strong>Zvonimir</strong> <strong>Koporc</strong> 3
Chirurgica Austrianica 34: 17, 2002<br />
4. Blaha P, Langer F, Bigen<strong>za</strong>hn S, <strong>Koporc</strong> Z, Selzer E, Bergmeister H,<br />
Mühlbacher F, Sykes M, Wekerle T: Minimal irradiation dose required for tolerance<br />
induction through bone marrow transplantation with costimulation blockade . European<br />
Surgery Acta Chirurgica Austrianica 34: 18, 2002<br />
5. Bigen<strong>za</strong>hn S, Blaha P, <strong>Koporc</strong> Z, Schmid M, Selzer E, Bergmeister H,<br />
Heusser C, Wagner K, Muehlbacher F, Wekerle T: Influence of an anti-CD25 mAb on<br />
tolerance induction through BMT with costimulation blockade. Journal of Heart and Lung<br />
Transplantation 22: 81, 2003<br />
6. Bigen<strong>za</strong>hn S, Blaha P, <strong>Koporc</strong> Z, Selzer E, Bergmeister H, Heusser C,<br />
Wagner K, Muehlbacher F, Wekerle T: Anti-CD25 mAb treatment inhibits tolerance<br />
induction through BMT with costimulation blockade. American Journal of Transplantation<br />
3: 455, 2003<br />
7. Blaha P, Bigen<strong>za</strong>hn S, <strong>Koporc</strong> Z, Muehlbacher F, Sykes M, Wekerle T:<br />
Short-course immunosuppression allows a reduction in the cell dose required for<br />
tolerance induction in a model using BMT with costimulation blockade without<br />
cytoreduction. European Surgery Acta Chirurgica Austrianica 35: 12, 2003<br />
8. <strong>Koporc</strong> Z, Blaha P, Bigen<strong>za</strong>hn S, Muehlbacher F, Sykes M, Wekerle T:<br />
Use of mobilized peripheral blood stem cells for the induction of mixed chimerism and<br />
tolerance. European Surgery Acta Chirurgica Austrianica 35: 12, 2003<br />
9. Blaha P, Bigen<strong>za</strong>hn S, <strong>Koporc</strong> Z, Muehlbacher F, Takeuchi Y, Sykes M,<br />
Wekerle T: Peripheral deletion of alloreactive T cells in a tolerance model using BMT<br />
and costimulation blockade cannot be elicited by the transplantation of separated B cells<br />
or den<strong>dr</strong>itic cells. European Surgery Acta Chirurgica Austrianica 35: 26, 2003<br />
10. Bigen<strong>za</strong>hn S, Blaha P, <strong>Koporc</strong> Z, Selzer E, Wrba F, Heusser C, Wagner K,<br />
Muehlbacher F, Wekerle T: The role of regulation for induction and maintenance of<br />
tolerance through BMT plus costimulation blockade. European Surgery Acta Chirurgica<br />
Austrianica 35: 27, 2003<br />
11. Bigen<strong>za</strong>hn S, Blaha P, <strong>Koporc</strong> Z, Muehlbacher F, Wekerle T: Progress<br />
towards clinical tolerance induction through mixed chimerism. European Surgery Acta<br />
Chirurgica Austrianica 35: 7, 2003<br />
12. Blaha P, Bigen<strong>za</strong>hn S, <strong>Koporc</strong> Z, Schmid M, Langer F, Selzer E,<br />
Bergmeister H, Wrba F, Kurtz J, Kiss C, Roth E, Muehlbacher F, Sykes M, Wekerle T:<br />
The influence of immunosuppressive <strong>dr</strong>ugs on tolerance induction through bone marrow<br />
transplantation with costimulation blockade. European Surgery Acta Chirurgica<br />
Austrianica 36: 7-8, 2004<br />
13. Blaha P, Bigen<strong>za</strong>hn S, <strong>Koporc</strong> Z, Muehlbacher F, Sykes M, Wekerle T:<br />
Transient immunosuppression allows a reduction in the cell dose required for tolerance<br />
induction through BMT with costimulation blockade without cytoreduction. Proc. Basic<br />
Sciences Symposium 2003 of The Transplantation Society 2003<br />
14. Bigen<strong>za</strong>hn S, Blaha P, <strong>Koporc</strong> Z, Selzer E, Heusser C, Wagner K ,<br />
Muehlbacher F, Wekerle T: The role of regulation for induction and maintenance of<br />
tolerance through BMT plus costimulation blockade. Proc. Basic Sciences Symposium<br />
2003 of The Transplantation Society 2003<br />
15. <strong>Koporc</strong> Z, Bigen<strong>za</strong>hn S, Blaha P, Muehlbacher F, Sykes M, Wekerle T:<br />
The use of Mobilized peripheral blood stem cells for the induction of mixed chimerism<br />
and tolerance. XX international congress of the transplantation society, Vienna-Austria<br />
Congress Abstracts Supplement to Transplantation 78: 131, 2004<br />
Životopis Dr. Sc. <strong>Zvonimir</strong> <strong>Koporc</strong> 4
16. Blaha P, Bigen<strong>za</strong>hn S, <strong>Koporc</strong> Z, Muehlbacher F, Sykes M, Wekerle T:<br />
Short-term immunosuppressive therapy improves chimerism and tolerance development<br />
in a model using bone marrow transplantation plus costimulation blockade without<br />
cytoreduction. XX international congress of the transplantation society, Vienna-Austria<br />
Congress Abstracts Supplement to Transplantation 78: 41, 2004<br />
17. <strong>Koporc</strong> Z, Bigen<strong>za</strong>hn S, Blaha P, Wrba F, Muehlbacher F, Sykes M,<br />
Wekerle T: Mobilized peripheral blood stem cells show lower tolerogenic potential than<br />
bone marrow cells in recipients of costimulation blockade. American Journal of<br />
Transplantation 4: 324, 2004<br />
18. Blaha P, Bigen<strong>za</strong>hn S, <strong>Koporc</strong> Z, Muehlbacher F, Sykes M, Wekerle T:<br />
Short-course immunosuppression facilitates chimerism and tolerance in a noncytoreductive<br />
model using BMT and costimulation blockade. 6th International<br />
Conference on NEW TRENDS IN IMMUNOSUPPRESSION, Book of abstracts 42, 2004<br />
19. Pree I, Bigen<strong>za</strong>hn S, Nierlich P, <strong>Koporc</strong> Z, Blaha P, Langer F, Selzer E,<br />
Fuchs D, Winkler C, Brandacher G, Sykes M, Muehlbacher F, Wekerle T: The role of<br />
Indoleamine 2,3-Dioxygenase (IDO) in a Murine CTLA4Ig-Based Mixed Chimerism<br />
Model. Clinical Immunology Supplement 1: 279, 2005<br />
20. <strong>Koporc</strong> Z, Uporaba mobiliziranih krvotnih maticnih celic iz periferrne krvi<br />
(mPBSC) <strong>za</strong> indukcijo mesanega himerizma in tolerance, DELO-ZNANOST,26, 2007<br />
21. <strong>Koporc</strong> Z, Razlike u kapacitetu indukcije stanja miješanog kimerizma i<br />
tolerancije mobiliziranih perifernih krvnih matičnih stanica (mPBSC) u usporedbi s<br />
koštanom srži (BM), Zavod <strong>za</strong> molekularnu medicinu IRB, pristupno predavanje, 2009<br />
Životopis Dr. Sc. <strong>Zvonimir</strong> <strong>Koporc</strong> 5
Change language