Zhen Yuan Curriculum Vitae - Biomedical Engineering - University ...
Zhen Yuan Curriculum Vitae - Biomedical Engineering - University ...
Zhen Yuan Curriculum Vitae - Biomedical Engineering - University ...
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<strong>Zhen</strong> <strong>Yuan</strong><br />
<strong>Curriculum</strong> <strong>Vitae</strong><br />
Name: <strong>Zhen</strong> <strong>Yuan</strong> (Ph.D.)<br />
Position Title: Research Assistant Professor<br />
Postal Address: Room 289, 1275 Center Drive, JG56 BMS Building, POB<br />
116131, Gainesville, FL 32611<br />
E-mail: yzhen@bme.ufl.edu<br />
Tel: 352-273-9330(O)<br />
Positions, Employment and Education<br />
09/2007- Research Assistant Professor, <strong>Biomedical</strong> <strong>Engineering</strong><br />
Department, <strong>University</strong> of Florida. Research Field: <strong>Biomedical</strong><br />
Imaging and <strong>Biomedical</strong> Optics.<br />
01/2005-09/2007 Postdoctoral Research Associate, <strong>Biomedical</strong> <strong>Engineering</strong><br />
Department, <strong>University</strong> of Florida, Gainesville, FL32611. Research<br />
Field: <strong>Biomedical</strong> Imaging and Signal Processing.<br />
03/2004-01/2005 Postdoctoral Research Fellow, Department of Physics, Clemson<br />
<strong>University</strong>, SC29634. Research Field: <strong>Biomedical</strong> Optical Imaging.<br />
03/2002-03/2004 Postdoctoral Research Scientist, Institute of High performance<br />
Computing, National <strong>University</strong> of Singapore, Singapore 117523.<br />
Research Field: BioMEMS.<br />
06/2002 Ph.D., <strong>University</strong> of Science and Technology of China (USTC),<br />
Hefei 230026, China. Major: Computational <strong>Engineering</strong><br />
(Biomechanics).<br />
Professional Services<br />
Member of SPIE<br />
Senior Member of OSA<br />
Member of IEEE<br />
Member of <strong>Biomedical</strong> <strong>Engineering</strong> Society<br />
Reviewers of IEEE Transactions on <strong>Biomedical</strong> <strong>Engineering</strong>, IEEE Transactions on<br />
<strong>Biomedical</strong> Imaging, Applied Optics, Optics Letter, Optics Express,<br />
JOSA A, Medical Physics, Physics in Medicine & Biology, Arthritis &<br />
Rheumatism, <strong>Biomedical</strong> Optics Express, Journal of <strong>Biomedical</strong> Optics,<br />
Journal of X-ray Science & Technology<br />
Research Interest<br />
I: <strong>Biomedical</strong> Imaging and Signal Processing<br />
• Diffuse Optical Imaging & Spectroscopy<br />
• Photoacoustic Imaging & Spectroscopy<br />
• EEG Source Localization and Signal Processing
• X-ray image reconstruction techniques<br />
• Molecular Imaging based on Fluorescent and Bioluminescent Tomography<br />
• Multi-modality Imaging<br />
• Photon Transport in Biological Tissues<br />
II: Neurosciences<br />
• Neurovascular and Neurometabolic Coupling<br />
• Brain Connectivity, Brain (Neuron) Network and Brain Plasticity<br />
• Data Driven and Model Based Neural Signal Analysis Methods<br />
• Neuroinformatics & Computational Informatics<br />
• Epilepsy, Neurocognitive Processing<br />
III: Modeling and Simulation, Computational <strong>Engineering</strong><br />
• Inverse Problems, Optimization methods, Numerical Solution of Partial<br />
Differential Equations, Statistical Methods<br />
• Reconstruction Algorithms and Signal Processing Methods<br />
• High Performance Numerical Methods: Meshless Method, Incompatible and<br />
Hybrid Finite Element Methods, Boundary Element methods.<br />
• Modeling and Simulation in Multiphysics<br />
• High Performance Computing: Cluster-based Parallel Computation and CPU-<br />
GPU-based Parallel Computing<br />
• Image Segmentation and Classification, Partial Correlation and Coherence<br />
Analysis, Partial Mutual Information Analysis, Granger Causality Analysis<br />
• Structural, Functional and Effective Connectivity Methods<br />
Programming Skills<br />
Matlab, C++/C, Fortran, ANSYS, Autocad, PATRAN, Abaqus, NASTRAN<br />
Teaching Interests<br />
• High Performance Numerical Methods, High Performance Computing<br />
• Finite Element Method, Biostatistics Methods<br />
• <strong>Biomedical</strong> <strong>Engineering</strong> Introduction, <strong>Biomedical</strong> Optics, <strong>Biomedical</strong> imaging and<br />
Signal Processing, Applied Optics, <strong>Biomedical</strong> Instrumentations,<br />
Neuroengineering<br />
• Multivariate Signal Processing Method<br />
Academic Service<br />
• 2007-2010 Served as a member of the Supervisory Committee for 3 Ph. D<br />
candidates in <strong>Biomedical</strong> <strong>Engineering</strong> Dept. at the <strong>University</strong> of Florida<br />
• 2009 Reviewed grant proposals for the National Medical Research Council<br />
(Singapore)<br />
• 2007-2010 Mentored 4 graduate students in <strong>Biomedical</strong> <strong>Engineering</strong> Dept. at<br />
<strong>University</strong> of Florida<br />
• 2006-2010(Summer) Mentored 5 high school students in the Innovation program<br />
at the <strong>University</strong> of Florida<br />
Editorial board<br />
Editorial board member of Journal of Biosensors and Bioelectronics<br />
Guess Associate Editor of Medical Physics<br />
Guess Associate Editor of Applied Optics
Honors and Fellowships<br />
“Lixue Pandeng” Scholarship of Chinese Academy of Sciences<br />
Postdoctoral Fellowship of ASTAR (Singapore)<br />
<strong>University</strong> of Florida: High performance Computing Fellowship (2006)<br />
2008, 2009, 2010 &2011 “Who is Who in America”<br />
2009 ,2010 &2011 “Who is Who in the World”<br />
2010,2011 “Who is Who in Medicine”<br />
2011 “Who is Who in Science and <strong>Engineering</strong><br />
Professional Experience<br />
Research Assistant Professor<br />
Dates (July 07 – present)<br />
Dept of <strong>Biomedical</strong> <strong>Engineering</strong>, <strong>University</strong> of Florida, Gainesville, FL 32611<br />
(http://www.bme.ufl.edu)<br />
• Clinically investigated the combined optical and fluorescence<br />
imaging\spectroscopy of breast cancer with enhanced sensitivity and specificity<br />
• Provided a new multi-modality imaging strategy for x-ray guided three-dimensional<br />
diffuse optical tomography\spectroscopy of osteoarthritis with improved resolution<br />
and contrast<br />
• Combined EEG recording and optical tomography/spectroscopy for neurovascular<br />
and neurometabolic coupling<br />
• Granger causality statistical software development for brain connectivity<br />
• Photoacoustic tomography\spectroscopy of epilepsy with high imaging contrast<br />
and resolution<br />
• Research report preparation, NIH research grant applications<br />
• Multi-modality imaging setups development<br />
Postdoctoral Research Fellow<br />
Dates (Jan 05 – July 07)<br />
Dept of <strong>Biomedical</strong> <strong>Engineering</strong>, <strong>University</strong> of Florida, Gainesville, FL 32611<br />
(http://www.bme.ufl.edu)<br />
• Software development for quantitative photoacoustic tomography\spectroscopy<br />
• Diffuse optical imaging software development based on photon transport equation<br />
• Photoacoustic tomography for imaging nanoparticles<br />
• Manages a team of 3 students for photoacoustic imaging system development<br />
Postdoctoral Research Associate<br />
Dates (March 04 – Jan 05)<br />
Dept of Physics, Clemson <strong>University</strong>, Clemson, SC 29634<br />
(http://www.clemson.edu/ces/departments/physics-astro/)<br />
• Reconstruction algorithm development for diffuse optical imaging of breast cancer<br />
• Software development for diffuse optical spectroscopy of biological tissues<br />
• Reconstruction algorithm development for bioluminescence tomography
Postdoctoral Research Scientist<br />
Dates (March 02 – March 04)<br />
Institute of High Performance Computing, National <strong>University</strong> of Singapore,<br />
Singapore<br />
(http://www.ihpc.a-star.edu.sg/)<br />
• Model development and numerical simulation in multi-physics<br />
• Biomaterials development and Biomechanics application in BioMEMS.<br />
Teaching Experience<br />
Courses Taught<br />
Spring 2007-2010 Graduate course BME, titled “Advanced Mathematics and High<br />
Performance Numerical Methods” offered through the<br />
Department of <strong>Biomedical</strong> <strong>Engineering</strong> at <strong>University</strong> of Florida<br />
Courses Developed (Collaborate with Dr. Huabei Jiang)<br />
Spring 2007-2010, “<strong>Biomedical</strong> Imaging,” Graduate course in the Department of<br />
<strong>Biomedical</strong> <strong>Engineering</strong> at <strong>University</strong> of Florida<br />
Patent<br />
• Hybrid Photoacoustic Tomography (PAT) and Diffuse Optical Tomography (DOT):<br />
Methods and Algorithms, International Application No. PCT/US2008/055894.<br />
• METHOD AND APPARATUS FOR TOMOGRAPHIC IMAGING OF ABSOLUTE<br />
OPTICAL ABSORPTION COEFFICIENT IN TURBID MEDIA USING COMBINED<br />
PHOTOACOUSTIC AND DIFFUSING LIGHT MEASUREMENTS<br />
(WO/2009/011934)<br />
Book Chapters<br />
1. Z. <strong>Yuan</strong>, H. Jiang, “Photoacoustic tomography,” Advances in Optical<br />
Imaging for Clinical Medicine by Dr. N.V. Iftimia, Dr. W. Brugge, and Dr. D.X.<br />
Hammer (John Wiley and Sons Ltd);(http://www.wisepress.com/index.asp-Q-I-E-<br />
9780470619094-advances-in-optical-imaging-for-clinical-medicine,61860).<br />
2. Z. <strong>Yuan</strong>, H. Jiang, “Photoacoustic tomography for imaging nanoparticles,” in<br />
Cancer Nanotechnology by Drs. Stephen R. Grobmyer and Brij Moudgil.<br />
http://www.springer.com/978-1-60761-608-5.<br />
3. Z. <strong>Yuan</strong>, H. Jiang, “Diffuse Optical Tomography of osteoarthritis,” in<br />
Handbook of Biophotonics, Volume 2, Photonics for Health Care, Edited by<br />
Jurger Popp, Valery V. Tuchin, Arthur Chiou, and Stefan Heinemann. Published<br />
by Wiley-VCH (2011).
4. Z. <strong>Yuan</strong>, H. Jiang, “Optical Methods and Instrumentation in Brain Imaging and<br />
Therapy,” Invited Book Chapter by Springer.<br />
Selected Peer-Reviewed Articles<br />
<strong>Biomedical</strong> Imaging and Signal Processing<br />
1. Z. <strong>Yuan</strong>, HB Jiang, “Quantitative photoacoustic tomography: recovery of optical<br />
absorption coefficient maps of heterogeneous medium,” Applied Physics<br />
Letters 88, 231101APL 1-3 (2006).<br />
2. Z. <strong>Yuan</strong>, H.Z. Zhao, C.F. Wu, H.B. Jiang, “Imaging of small nanoparticle<br />
containing objects using finite element-based photoacoustic tomography,” Optics<br />
Letters 30, 3054-3056(2005).<br />
3. Z. <strong>Yuan</strong>, H. Jiang, “Simultaneous recovery of tissue physiological and acoustic<br />
properties and the criteria for wavelength selection in multispectral photoacoustic<br />
tomography,” Optics Letters 34, 1714-1716 (2009).<br />
4. Z. <strong>Yuan</strong>, Q. Zhang, H.B. Jiang, “3D diffuse optical tomography imaging of<br />
osteoarthritis: initial results in the finger joints,” Journal of <strong>Biomedical</strong> Optics<br />
12(3), 034001 (2007).<br />
5. Z. <strong>Yuan</strong>, Q. Zhang, E. Sobel, H. Jiang, “Tomographic x-ray-guided 3D diffuse<br />
optical tomography imaging of osteoarthritis: Initial results in the finger joints,”<br />
Journal of <strong>Biomedical</strong> Optics 13, 044006 (2008).<br />
6. Z. <strong>Yuan</strong>, Q. Zhang, E. Sobel, H. Jaign, “Comparison of diffusion approximation<br />
and higher order diffusion equation for optical tomography of osteoarthritis,”<br />
Journal of <strong>Biomedical</strong> Optics 14, 054013(2009).<br />
7. Z. <strong>Yuan</strong>, Q. Wang, H. Jiang, “Reconstruction of optical absorption coefficient<br />
maps of heterogeneous medium by photoacoustic tomography coupled with<br />
diffusion equation based regularized Newton Method,” Optics Express 15,<br />
18078-18081(2007).<br />
8. Z. <strong>Yuan</strong>, Q. Zhang, H. Jiang, “Simultaneous reconstruction optical and acoustic<br />
properties by quantitative photoacoustic tomography,” Optics Express 14, 6749-<br />
6754 (2006).<br />
9. Z. <strong>Yuan</strong>, H.Z. Zhao, H.B. Jiang, “Finite element-based photoacoustic<br />
tomography: phantom and chicken bone experiments,” Applied Optics 45(13),<br />
3177-3183(2006).<br />
10. Z. <strong>Yuan</strong>, H.B. Jiang, “An image reconstruction scheme that combines modified<br />
Newton method and efficient initial guess estimation for optical tomography of<br />
finger joints,” Applied Optics 46, 2757-2768 (2007).<br />
11. Z. <strong>Yuan</strong>, H.B. Jiang, “Three-dimensional finite element-based photoacoustic<br />
tomography: Reconstruction algorithm and simulations,” Medical Physics 34(2),<br />
538-546(2007).<br />
12. Z. <strong>Yuan</strong>, H. Jiang, “Quantitative photoacoustic tomography,” Philosophical<br />
Transaction of the Royal Society A 367, 3043-3054 (2009).<br />
13. Z. <strong>Yuan</strong>, X. Hu, H. Jiang, “A higher order diffusion model for three-dimensional<br />
photon migration and image reconstruction in optical tomography,” Physics in<br />
Medicine and Biology 54,65-88(2009).<br />
14. Z. <strong>Yuan</strong>, H. Jiang. “High resolution x-ray guided three dimensional diffuse optical<br />
tomography of joint tissues in hand osteoarthritis: Morphological and functional<br />
assessments,” Medical Physics, 37 (8), 2010.
15. Z. <strong>Yuan</strong>, Q. Zhang, E. Sobel, H. Jiang, “Image-guided optical spectroscopy in<br />
diagnosis of osteoarthritis: A clinical study,” <strong>Biomedical</strong> Optics Express 1, 74-<br />
86(2010).<br />
16. H.B. Jiang, Z. <strong>Yuan</strong>, X.J. Gu, “Spatially varying optical and acoustic property<br />
reconstruction using finite element-based photoacoustic tomography,” Journal of<br />
the Optical Society of America A 23(4), 878-888 (2006).<br />
17. J. Xiao, Z. <strong>Yuan</strong>, H. Jiang, “Quantitative multispectral photoacoustic tomography<br />
and wavelength optimization,” Journal of X-Ray Science and Technology, 02<br />
(2010).<br />
18. Q. Zhang, L. Yin, Y. Tan, Z. <strong>Yuan</strong>, H. Jiang, “Quantitative bioluminescence<br />
tomography guided by diffuse optical tomography,” Optics Express 16, 1481-<br />
1483 (2008).<br />
19. Z. <strong>Yuan</strong>, “Recent advances in Nano imaging using photoacoustic<br />
measurements” Nano express 2011 (invited paper).<br />
20. Q. Zhang, Z. Liu, P. Camey, Z. <strong>Yuan</strong>, H. Jiang, “Noninvasive imaging of epileptic<br />
seizure in vivo using photoacoustic tomography,” Physics in Medicine and<br />
Biology 53(7),1921-1931(2008).<br />
21. J. Zhang, Z. Wang, Z. <strong>Yuan</strong> and H. Jiang, “Computer aided classification of<br />
optical images for diagnosis of osteoarthritis in the finger joints,” Journal of X-<br />
Ray Science and Technology, 2011 (accepted).<br />
22. Z. <strong>Yuan</strong>, H. Jiang, “A more vigorous quantitative photoacoustic tomography<br />
reconstruction method,” Journal of <strong>Biomedical</strong> Optics Letters, 2011 (in review).<br />
23. Z. <strong>Yuan</strong>, Q. Zhang, H. Jiang. “X-ray guided three-dimensional diffuse optical<br />
imaging of the finger joints in osteoarthritis and psoriatic arthritis: A comparable<br />
study,” Journal of <strong>Biomedical</strong> Optics (in review).<br />
Computational Bioengineering and Computational <strong>Engineering</strong><br />
24. H. Li, Z. <strong>Yuan</strong>, K.Y. Lam et al., “Model development and numerical simulation of<br />
electric-stimulus-responsive hydrogels subject to external electric field,”<br />
Biosensors and Bioelectronics19 (9), 1097-1107 (2004).<br />
25. H. Li, Z. <strong>Yuan</strong>, T.Y. Ng, K.Y. Lam, “Constitutive model development and<br />
microstructural topology optimization for Nafion hydrogel membrane with ionic<br />
clustering,” Journal of Biomaterials Science-Polymer Edition.14, 1181-1196<br />
(2003).<br />
26. L. Yin, Z. <strong>Yuan</strong>, L.H. He, “Model development and numerical simulation of<br />
temperature-sensitive hydrogels,” Computational Materials Sciences 31, 299-<br />
308 (2004).<br />
27. Z. <strong>Yuan</strong>, C.C. Wu, Hua Li, “Homogenized-based topology design for pure torsion<br />
of composite shafts,” ACTA MECHANICA SINICA 19(3), 241-246(2003).<br />
28. L. Yin, Z. <strong>Yuan</strong> et al., “Model development and numerical simulation of<br />
biohydrogels in aqueous salt solutions,” ACTA MECHANICA SINICA 37(3), 363-<br />
367(2005).<br />
29. Z. <strong>Yuan</strong>, C.C. Wu, “Topology optimization for microstructures of cross-section of<br />
composite torsional shafts,” ACTA MECHANICA SINICA, 35(1): 39-42(2003).<br />
30. Z. <strong>Yuan</strong>, C.C. Wu, “Topology optimization of continuum structures using<br />
incompatible finite elements,” ACTA MECHANICA SINICA 35(2), 176-180(2003).<br />
31. Z. <strong>Yuan</strong>, C.C. Wu, “Topology optimization for periodic linear elastic<br />
microstructures of composite materials,” ACTA MECHANICA SOLIDA SINICA<br />
24(1), 40-45(2003).
32. Z. <strong>Yuan</strong>, C.C. Wu, “Numerical simulation of mechanical properties of prestress<br />
concrete members due to creep and shrinkage,” ACTA MECHANICA SOLIDA<br />
SINICA 24, 298-303(2001).<br />
33. Z. <strong>Yuan</strong>, Z.R. Li, C.C. Wu, “Simulation of Mixed-mode Fatigue Crack Growth by<br />
Element Free Galerkin Method,” <strong>Engineering</strong> Mechanics 19(1), 25-28(2002).<br />
34. Z. <strong>Yuan</strong>, Y. Liu, “Effective method for dynamic analysis of interaction of fluid and<br />
structure of mechanical equipment,” Journal of Mechanical Strength (1), 16-<br />
17(2000).<br />
35. Z. <strong>Yuan</strong>, C.C. Wu, “Analytical respond sensitivity computation using incompatible<br />
elements,” Journal of Mechanical Strength 24(1), 59-61(2002).<br />
36. Z. <strong>Yuan</strong>, C.C. Wu, “Topology optimization of continuum structure using hybrid<br />
elements and artificial material model,” Journal of China <strong>University</strong> of Science<br />
and Technology 31 (6), 694-699(2001). (In Chinese with English Abstract)<br />
37. S. Zhuang, C.C. Wu, Z. <strong>Yuan</strong>, “Microscopic investigation of cellular materials<br />
mechanical properties based on homogenization theory,” Materials Science and<br />
<strong>Engineering</strong> 19(4), 9-13(2001). (In Chinese with English Abstract)<br />
Neuroimaging and Neuroinformatics<br />
38. J. Zhang, T. Guo and Z. <strong>Yuan</strong>, “Analysis of fMRI Data Using an Integrated<br />
Principal Component Analysis and Supervised Affinity Propagation Clustering<br />
Approach,” IEEE Transaction on <strong>Biomedical</strong> <strong>Engineering</strong>,2011(8),PMID:<br />
21859596.<br />
39. Q. Zhang, Z. Liu, P. Camey, Z. <strong>Yuan</strong>, H. Jiang, “Noninvasive imaging of epileptic<br />
seizure in vivo using photoacoustic tomography,” Physics in Medicine and<br />
Biology 53(7),1921-1931(2008).<br />
40. Z. <strong>Yuan</strong>, H. Jiang, “A nonlinear reconstruction method for EEG source locations,”<br />
IEEE Transactions on <strong>Biomedical</strong> Imaging, 2011 (in review).<br />
41. Z. <strong>Yuan</strong>, H. Jiang, “Investigation of brain effective connectivity in epilepsy using<br />
diffuse optical measurement, “ASE 2011 Conference.<br />
42. R. Jiang, Z. <strong>Yuan</strong>, H. Jiang. “Imaging the blood flow and cellular morphology in<br />
epilepsy with diffuse optical tomography,” 2010 Technical Digest of OSA<br />
<strong>Biomedical</strong> Optics Topical Meeting, Miami, Florida, USA. April.<br />
Invited International Conference Presentations<br />
1. Z. <strong>Yuan</strong>, H. Jiang. Three-dimensional finite element-based PAT: initial results,<br />
Proc. SPIE 6437, 64371A, 2007.<br />
2. Z. <strong>Yuan</strong>, L. Yin, H. Jiang. Numerical simulation of transient nonlinear behaviors<br />
of electric-sensitive hydrogel membrane under an external electric field, Proc.<br />
SPIE 6465, 64650W, 2007.<br />
3. Z. <strong>Yuan</strong>, Q. Zhang, Y. Sun, H. Jiang. Simultaneous reconstruction of acoustic<br />
and optical properties of in-vivo tissues by PAT, Proc. SPIE 6437, 64371V,<br />
2007.<br />
4. Z. <strong>Yuan</strong>, Q. Zhang, H.B. Jiang. Diagnosis of osteoarthritis in the finger joints by<br />
three-dimensional diffuse optical tomography: Pilot clinical results. 2006<br />
Technical Digest of OSA <strong>Biomedical</strong> Optics Topical Meeting, Fort Lauderdale,<br />
Florida, USA, March 19–23, 2006.
5. Z. <strong>Yuan</strong>, Q. Zhang, Y. Sun, H. Jiang. Simultaneous reconstruction of acoustic<br />
and optical properties of in-vivo tissues by PAT, Proc. SPIE 6437, 64371V,<br />
2007.<br />
6. Z. <strong>Yuan</strong>, H. Jiang. Simultaneous recovery of chromophore concentrations and<br />
ultrasound velocity by PAT. Proc. SPIE BO203, 63, 2009.<br />
7. Z. <strong>Yuan</strong>, H. Jiang. X-ray guided 3D DOT imaging of OA finger joints: a clinical<br />
study. Proc. SPIE BO110, 11, 2009.<br />
8. Z. <strong>Yuan</strong>, H. Jiang. Diffuse optical imaging of OA finger joints by higher-order<br />
diffuse equations. Proc. SPIE BO118, 68, 2009.<br />
9. H, Jiang, Z. <strong>Yuan</strong>. Quantitative photoacoustic tomography: recover of optical<br />
absorption coefficient maps of heterogeneous media, Proc. SPIE 6437, 64371S,<br />
2007.<br />
10. Q. Zhang, Z. <strong>Yuan</strong>, H. Jiang, X-ray guided 3D diffuse optical tomography: in<br />
vivo study of osteoarthritis in the finger joints, Proc. SPIE 6431, 643112, 2007.<br />
11. Z. <strong>Yuan</strong>, H. Li, Ng T. Y. and J. Chen. A coupled multi-field formulation for<br />
stimuli-responsive hydrogel subject to electric field, Proceeding of the<br />
International Conference on Scientific & <strong>Engineering</strong> Computation (IC-<br />
SEC):884-887, Singapore, 2002.<br />
12. Z. <strong>Yuan</strong>, L. Yin, C.C. Wu et al. Topology optimization of continuum structures<br />
using high performance finite elements, Proceeding of the 4th International<br />
Conference on Nonlinear Mechanics: 717-720, Shanghai, China, 2002.<br />
13. Z. <strong>Yuan</strong> et al. “Image-guided photoacoustic spectroscopy in diagnosis of<br />
osteoarthritis,” 2011 Photonics West, SPIE, California.<br />
14. Z. <strong>Yuan</strong> et al., “ The diffuse optical imaging of epilepsy network in small<br />
animal,” ASE 2010, Texas.<br />
International Conference Papers<br />
1. Z. <strong>Yuan</strong>, Q.Z. Zhang, H.B. Jiang. 3D diffuse optical tomography of finger joints<br />
based on globally convergent methods and enhanced initial values optimization<br />
scheme. 2006 Technical Digest of OSA <strong>Biomedical</strong> Optics Topical Meeting, Fort<br />
Lauderdale, Florida, USA, March 19–23, 2006.<br />
2. Z. <strong>Yuan</strong>, Q. Wang, H.B. Jiang. Recovery of Absolute Absorption Coefficient<br />
Maps of Heterogeneous Media by Photoacoustic Tomography Coupled with<br />
Diffusion Optical Reconstruction Algorithm. 2008 Technical Digest of OSA<br />
<strong>Biomedical</strong> Optics Topical Meeting, Florida, USA, March 16–20.<br />
3. Z. <strong>Yuan</strong>, X. Hu, H. Jiang. A Simplified Spherical Harmonics Approximated<br />
Radiation Transport Model for Three Dimensional (3-D) Photon Migration in<br />
Small Volume Tissues. 2008 Technical Digest of OSA <strong>Biomedical</strong> Optics<br />
Topical Meeting, Florida, USA, March 16–20.<br />
4. Z. <strong>Yuan</strong>, Q.Z. Zhang, H.B. Jiang. A clinical investigation on x-ray guided<br />
three-dimensional diffuse optical imaging of osteoarthritis in the finger<br />
joints. 2010 Technical Digest of OSA <strong>Biomedical</strong> Optics Topical Meeting, Miami,<br />
Florida, USA. April.<br />
5. Z. <strong>Yuan</strong>, H.B. Jiang. Diffusion approximation and higher-order diffusion<br />
equations for optical tomography of osteoarthritis: A comparable study. 2010<br />
Technical Digest of OSA <strong>Biomedical</strong> Optics Topical Meeting, Miami, Florida,<br />
USA. April.<br />
6. Z. <strong>Yuan</strong>, Q. Zhang, E. Sobel, H. Jiang. Imaging molecular signatures for<br />
detection of osteoarthritis by combining spectral and spatial a-priori information.
2010 Technical Digest of OSA <strong>Biomedical</strong> Optics Topical Meeting, Miami,<br />
Florida, USA. April.<br />
7. Z. <strong>Yuan</strong>, Q. Zhang, E. Sobel, H. Jiang. X-ray guided three-dimensional diffuse<br />
optical tomography of osteoarthritis and psoriatic arthritis in finger joints: A<br />
comparable study. 2010 Technical Digest of OSA <strong>Biomedical</strong> Optics Topical<br />
Meeting, Miami, Florida, USA. April.<br />
8. Z. <strong>Yuan</strong>, H.B. Jiang. Simultaneous recovery of tissue physiological and acoustic<br />
properties and uniqueness in multi-spectral photoacoustic tomography. 2010<br />
Technical Digest of OSA <strong>Biomedical</strong> Optics Topical Meeting, Miami, Florida,<br />
USA. April.<br />
9. H, Jiang, Z. <strong>Yuan</strong>. Quantitative photoacoustic tomography: recover of optical<br />
absorption coefficient maps of heterogeneous media, Proc. SPIE 6437, 64371S,<br />
2007.<br />
10. Q. Zhang, Z. <strong>Yuan</strong>, H. Jiang, X-ray guided 3D diffuse optical tomography: in<br />
vivo study of osteoarthritis in the finger joints, Proc. SPIE 6431, 643112, 2007.<br />
11. Qizhi Zhang, Lu Yin, Yiyong Tan, Z. <strong>Yuan</strong>. Three-Dimensional Bioluminescence<br />
Tomography Assisted by Diffuse Optical Tomography. 2008 Technical Digest of<br />
OSA <strong>Biomedical</strong> Optics Topical Meeting, Florida, USA, March 16–20.<br />
12. Z. <strong>Yuan</strong>, C. Wu. Numerical problem study on structural topology optimization,<br />
Proceedings of the 11 th National Computational Mechanics Conference,<br />
Guangzhou, China, 2001.<br />
13. Q. Zhang, Z. <strong>Yuan</strong>. “In vivo x-ray guided optical tomography of osteoarthritis in<br />
the knee joints,” 2010 Technical Digest of OSA <strong>Biomedical</strong> Optics Topical<br />
Meeting, Miami, Florida, USA. April.<br />
14. R. Jiang, Z. <strong>Yuan</strong>, H. Jiang. “Imaging the blood flow and cellular morphology in<br />
epilepsy with diffuse optical tomography,” 2010 Technical Digest of OSA<br />
<strong>Biomedical</strong> Optics Topical Meeting, Miami, Florida, USA. April.<br />
15. Q. Zhang, Z. <strong>Yuan</strong>, H. Jiang. “Diffuse Optical Tomography of large joints: a<br />
phantom study,” 2010 Technical Digest of OSA <strong>Biomedical</strong> Optics Topical<br />
Meeting, Miami, Florida, USA. April.<br />
16. Q. Zhang, Z. <strong>Yuan</strong>, H. Jiang. “Imaging osteoarthritis in the knee joints using x-<br />
ray guided diffuse optical tomography,” SPIE 7548, 2010.