Benjamin J. Fregly - Biomedical Engineering - University of Florida

Benjamin J. Fregly
Department of Mechanical and Aerospace Engineering Tel: (352) 392-8157
231 MAE-A Building, P.O. Box 116250 Fax: (352) 392-7303
University of Florida
E-mail: fregly@ufl.edu
Gainesville, FL 32611-6250
Web: www.mae.ufl.edu/~fregly
EDUCATION
1982-1986 Princeton University, Mechanical and Aerospace Engineering Department, Princeton, NJ.
B.S. (Magna Cum Laude) in Mechanical Engineering.
1986-1987 Stanford University, Mechanical Engineering Department (Design Division), Stanford, CA.
M.S. in Mechanical Engineering.
1987-1993 Stanford University, Mechanical Engineering Department (Design Division), Stanford, CA.
Ph.D. in Mechanical Engineering.
Emphasis: Dynamics, design, and control of mechanical and biomechanical systems.
1993-1994 University of Lyon, Center for Mechanics, Lyon, France.
Chateaubriand Post-doctoral Fellowship in Biomechanics.
Emphasis: Three-dimensional kinematic analyses of human movement.
PROFESSIONAL EXPERIENCE
1987-1993 Research Assistant, Mechanical Engineering Department (Design Division), Stanford University,
Stanford, CA and Rehabilitation Research and Development Center, Veterans Administration
Medical Center, Palo Alto, CA.
1993-1994 Post-doctoral Fellow, Center for Mechanics, University of Lyon, Lyon, France.
1994-1995 Consultant, Motion Analysis Corporation, Santa Rosa, CA.
1995-1996 Project Group Leader, Mechanica Division, Parametric Technology/Rasna Corporation, San
Jose, CA.
1996-1999 Research and Development/Software Engineer, Mechanica Division, Parametric Technology
Corporation, San Jose, CA.
1999-present
Assistant Professor, Department of Mechanical & Aerospace Engineering, Department of
Biomedical Engineering (joint), and Department of Orthopaedics and Rehabilitation
(courtesy), University of Florida, Gainesville, FL.
PROFESSIONAL MEMBERSHIPS
1986-present
1988-present
Member, American Society of Mechanical Engineers
Member, American Society of Biomechanics
HONORS
1986 Tau Beta Pi National Engineering Honor Society.
1986-1987 Graduate Student Fellowship, Mechanical Engineering Department, Stanford University.
1993-1994 Chateaubriand Post-doctoral Fellowship, Dept. of Science and Technology, French Government.
2000-2001 Teacher of the Year Award, Dept. of Mechanical & Aerospace Engineering, University of Florida.
2003 Who’s Who Among America’s Teachers
2003-2008 NSF CAREER Award

Benjamin J. Fregly 2
GRANT REVIEWER
NIH Special Emphasis Panel - Biomechanical Modeling of Human Movement, NICHD/NCMRR, Nov 19-20, 2003.
NIH Neuroprosthesis Bioengineering Research Partnership Study Section ZRG1 (Invited), Jul 11, 2003.
NSF Biomedical Engineering and Research to Aid Persons with Disabilities Unsolicited Panel, Jan 14-15, 2003.
NSF Biomedical Engineering and Research to Aid Persons with Disabilities CAREER Panel, Nov 6-7, 2001.
JOURNAL REVIEWER
Clinical Orthopaedics and Related Research
Gait and Posture
Journal of Biomechanics
Journal of Biomechanical Engineering
Medicine and Science in Sports & Exercise
RESEARCH SUPPORT
Fregly, B.J. (PI), Surgery Simulation of High Tibial Osteotomy, Whitaker Foundation Biomedical Engineering
Research Grant, 9/1/2001 - 8/24/2004, $239,979.
Fregly, B.J. (PI), Contact Stress Testing of Artificial Knees, Exactech Corporation, 9/18/2001 - 12/15/2002,
$22,500.
Fregly, B.J. (PI), A Computational Framework for Simulating Joint Mechanics, NIH National Library of Medicine
R03 Grant, 5/1/2002 - 4/30/2005, $206,874.
Fregly, B.J. (PI), Virtual Testing of a Total Knee Replacement Design, Stryker Howmedica Osteonics, 4/1/2003 -
12/1/2004, $12,500.
Fregly, B.J. (PI), Virtual Prototyping of Artificial Knees, NSF BES CAREER Award, 5/1/2003 - 4/30/2008,
$400,000.
PUBLICATIONS
*Graduate student supervised by Dr. Fregly
† Corresponding author
Journal Articles - Published or Accepted for Publication
1. Banks, S. A. † , Fregly, B. J. , Boniforti, F., Reinschmidt, C., and Romagnoli, S. (2004) Comparing in vivo
kinematics of unicondylar and bi-unicondylar knee replacements. Knee Surgery, Sports Traumatology, and
Arthroscopy (accepted).
2. Bei, Y.*, Fregly, B. J. † , Sawyer, W. G., Banks, S. A., and Kim, N. H. (2004) The relationship between contact
pressure, insert thickness, and mild wear in total knee replacements. Computer Modeling in Engineering &
Sciences (accepted).
3. Fregly, B. J. † , Sawyer, W. G., Harman, M. K., and Banks, S. A. (2004a) Computational wear prediction of a
total knee replacement from in vivo kinematics. Journal of Biomechanics special issue on the knee (accepted).
4. Koh, B. I.*, Reinbolt, J. A.*, Fregly, B. J. † , and George, A. D. (2004) Evaluation of parallel decomposition
methods for biomechanical optimizations. Computer Methods in Biomechanics and Biomedical Engineering
(accepted).
5. Reinbolt, J. A.*, Schutte, J. F.*, Fregly, B. J. † , Haftka, R. T., George, A. D., and Mitchell, K. H. (2004)
Determination of patient-specific multi-joint kinematic models through two-level optimization. Journal of
Biomechanics (accepted).
6. Sawyer, W. G. † , Hamilton, M. A., Sucec, M. C., Fregly, B. J. , and Banks, S. A. (2004) Quantifying
multidirectional sliding motions in total knee replacements, Journal of Tribology (accepted).

Benjamin J. Fregly 3
7. Schutte, J. F.*, Reinbolt, J. A.*, Fregly, B. J. † , Haftka, R. T., and George, A. D. (2004a) Parallel global
optimization with the particle swarm algorithm. International Journal for Numerical Methods in Engineering
(accepted).
8. Fregly, B. J. † , Bei, Y.*, and Sylvester, M. E.* (2003) Experimental evaluation of an elastic foundation model to
predict contact pressures in knee replacements. Journal of Biomechanics 36, 1659-1668.
9. Fregly, B. J. † and Sawyer, W. G. (2003) Estimation of discretization errors in contact pressure measurements,
Journal of Biomechanics 36, 609-613.
10. Sawyer, W. G. † , Hamilton, M. A., Fregly, B. J. , and Banks, S. A. (2003) Temperature modeling in a total knee
joint replacement using patient-specific kinematics. Tribology Letters 15, 343-351.
11. Hansen E. A. † , Jorgensen L. V., Jensen K., Fregly B. J. , Sjogaard G. (2002) Crank inertial load affects freely
chosen pedal rate during cycling. Journal of Biomechanics 35, 277-285.
12. Fregly, B. J. † , Zajac, F. E., and Dairaghi, C. A. (2000) Bicycle drive system dynamics: theory and experimental
validation. Journal of Biomechanical Engineering 122, 446-452.
13. Chèze, L. † , Fregly, B. J. , and Dimnet, J. (1998) Determination of joint functional axes from noisy marker data
using the finite helical axis. Human Movement Science 17, 1-15.
14. Fregly, B. J. and Zajac, F. E. † (1996) A state-space analysis of mechanical energy generation, absorption, and
transfer during pedaling. Journal of Biomechanics 29, 81-90.
15. Fregly, B. J. , Zajac, F. E. † , and Dairaghi, C. A. (1996) Crank inertial load has little effect on steady-state
pedaling coordination. Journal of Biomechanics 29, 1559-1567.
16. Chèze, L. † , Fregly, B. J. , and Dimnet, J. (1995) A solidification procedure to facilitate kinematic analyses based
on video system data. Journal of Biomechanics 28, 879-884.
Journal Articles - Conditionally Accepted Pending Revisions
17. Bei, Y.* and Fregly, B. J. † (2004) Multibody dynamic simulation of knee contact mechanics. Medical
Engineering & Physics (conditionally accepted).
18. Fregly, B. J. † , Rahman, H.*, and Banks, S. A. (2004b) Accuracy analysis of model-based shape matching for
measuring natural knee kinematics with single-plane fluoroscopy. Journal of Biomechanical Engineering
(conditionally accepted).
19. Schutte, J. F.*, Koh, B.-I.*, Reinbolt, J. A.*, Fregly, B. J. † , Haftka, R. T., and George, A. D. (2004b)
Evaluation of the particle swarm algorithm for biomechanical optimization. Journal of Biomechanical
Engineering (conditionally accepted).
Conference Papers – Podium Presentations
1. Fregly, B. J. and Reinbolt, J. A.* (2004) Estimation of body segment parameters from three-dimensional gait
data using optimization. In Proceedings of the Eighth International Symposium on the 3D Analysis of Human
Movement, pp. 13-16, Tampa, FL.
2. Koh, B. I.*, Reinbolt, J. A.*, Fregly, B. J. , and George, A. D. (2004) Parallel decomposition methods for
biomechanical optimization. In Proceedings of the Eighth International Symposium on the 3D Analysis of
Human Movement, pp. 69-72, Tampa, FL.
3. Lin, Y.-C.* and Fregly, B. J. (2004) Experimental evaluation of a three-dimensional knee contact model using
response surface optimization. In Proceedings of the Eighth International Symposium on the 3D Analysis of
Human Movement, pp. 29-32, Tampa, FL.
4. Rooney, K.* and Fregly, B. J. (2004) An inverse dynamics optimization approach for predicting human
movement. In Proceedings of the Eighth International Symposium on the 3D Analysis of Human Movement, pp.
85-88, Tampa, FL.
5. Banks, S. A.., Fregly, B. J. , Reinschmidt, C., Boniforti, F., and Romagnoli, S. (2004) In vivo gait and stair
kinematics in patients with uni- and bi-unicondylar knee arthroplasty. of unicondylar and bi-unicondylar knee
replacements. In Proceedings of the 50th Annual Meeting of the Orthopaedic Research Society, Paper #0243,
San Francisco, CA.

Benjamin J. Fregly 4
6. Fregly, B. J. , Rahman, H.*, and Banks, S. A. (2004) An automated image matching procedure for measuring
natural knee kinematics with single-plane fluoroscopy. In Proceedings of the 50th Annual Meeting of the
Orthopaedic Research Society, Paper #0086, San Francisco, CA.
7. Banks, S. A., Romagnoli, S., Boniforti, F., Canciani, J. P., Fregly, B. J. , Reinschmidt, C., and Muenchinger, M.
(2003) Revisiting the bicruciate retaining knee arthroplasty. In Proceedings of the 16th Annual Symposium of
the International Society for Technology in Arthroplasty, San Francisco, CA.
8. Fregly, B. J. , Sawyer, W. G., Harman, M. K., Banks, S. A., and Hodge, W. A. (2003) Knee arthroplasty wear
prediction from in vivo kinematics. In Proceedings of the 16th Annual Symposium of the International Society
for Technology in Arthroplasty, San Francisco, CA.
9. Rahman, H.*, Fregly, B. J. , and Banks, S. A. (2003) Accurate measurement of three-dimensional natural knee
kinematics using single-plane fluoroscopy. In Proceedings of the 2003 Summer Bionengineering Conference
(Edited by Soslowsky, L.J., Skalak, T.C., Wayne, J.S., and Livesay, G.A.), pp. 465-466. The American Society
of Mechanical Engineers, New York.
10. Reinbolt, J. A.*, Schutte, J. F.*, Haftka, R. T., George, A. D., Mitchell, K. H., and Fregly, B. J. (2003)
Determination of patient-specific functional axes through two-level optimization. In Proceedings of the 2003
Summer Bionengineering Conference (Edited by Soslowsky, L.J., Skalak, T.C., Wayne, J.S., and Livesay,
G.A.), pp. 317-318. The American Society of Mechanical Engineers, New York.
11. Sawyer, W. G., Hamilton, M. A., Sucec, M. C., Fregly, B. J. , and Banks, S. A. (2003) Analysis of in vivo
crossing motion in total knee replacements. In Proceedings of the 2003 Summer Bionengineering Conference
(Edited by Soslowsky, L.J., Skalak, T.C., Wayne, J.S., and Livesay, G.A.), pp. 549-550. The American Society
of Mechanical Engineers, New York.
12. Schutte, J. F.*, Koh, B.*, Reinbolt, J. A.*, Haftka, R. T., George, A. D., and Fregly, B. J. (2003) Scaleindependent
biomechanical optimization. In Proceedings of the 2003 ASME Bionengineering Conference
(Edited by Soslowsky, L.J., Skalak, T.C., Wayne, J.S., and Livesay, G.A.), pp. 55-56. The American Society of
Mechanical Engineers, New York.
13. Romagnoli, S., Boniforti, F., Banks, S., Fregly, B. , and Reinschmidt, C. (2003) Deep flexion kinematics in bicruciate
retaining uni and bi-uni knee arthroplasty. In Proceedings of the 6 th
Congress of the European
Federation of National Associations of Orthopaedics and Traumatology (EFORT), p. 282, Helsinki, Finland.
14. Schutte, J. F.*, Fregly, B. J. , Haftka, R. T., and George, A. (2003) A parallel particle swarm algorithm. In
Proceedings of the Fifth World Congress of Structural and Multidisciplinary Optimization, Venice, Italy.
15. Fregly, B. J. (2000) Effect of femoral component malrotation on contact stress in total knee replacements. In
Proceedings of the 24th Annual Meeting of the American Society of Biomechanics, pp. 101-102. University of
Illinois at Chicago.
16. Fregly, B. J. (1999) A three-dimensional compliant contact model for dynamic simulation of total knee
replacements. In Proceedings of the VIIth International Symposium on Computer Simulation in Biomechanics,
pp. 10-13. University of Calgary, Calgary, Alberta, Canada.
17. Fregly, B. J. (1997) A measurement procedure to reduce pedaling inverse dynamics errors due to linkage model
inaccuracies. In Proceedings of the 1997 Summer Bioengineering Conference (Edited by Chandran, K. B.,
Vanderby, R., and Hefzy, M. S.), BED-vol 35, pp. 449-450. The American Society of Mechanical Engineers,
New York.
18. Fregly, B. J. and Whalen, R. T. (1995) Simulated changes in control strategy during altered gravity pedaling. In
Proceedings of the Nineteenth Annual Meeting of the American Society of Biomechanics, pp. 67-68. Stanford
University, Stanford, CA.
Conference Papers – Poster Presentations
19. Bei, Y.*, Fregly, B. J ., Sawyer, W. G., and Banks, S. A. (2004) Predicted sensitivity of knee implant wear to
insert thickness and body mass. In Proceedings of the 50th Annual Meeting of the Orthopaedic Research
Society, Paper #1465, San Francisco, CA.
20. Fregly, B. J. , Sawyer, W. G., Harman, M. K., and Banks, S. A. (2003) Computational prediction of in vivo wear
in total knee replacements. In Proceedings of the 2003 Summer Bionengineering Conference (Edited by
Soslowsky, L.J., Skalak, T.C., Wayne, J.S., and Livesay, G.A.), pp. 1171-1172. ASME, New York.

Benjamin J. Fregly 5
21. Banks, S. A., Boniforti, F, Fregly, B. J. , Rahman, H.*, Reinschmidt, C., and Romagnoli, S. (2003) The
kinematics of deep flexion in bi-cruciate retaining resurfacing knee arthroplasty. In Proceedings of the 49 th
Annual Meeting of the Orthopaedic Research Society, Paper #1323, New Orleans, LA.
22. Goede, T. E.* and Fregly, B. J. (2001) Computational Modeling of Musculskeletal Mechanics. NASA Human
Systems 2001 Conference: Exploring the Human Frontier, Johnson Space Center, Houston, TX, June 20-22.
INVITED SEMINARS
Georgia Institute of Technology, Biomedical Engineering Department, Atlanta, GA. April 24, 2004.
Cornell University, Mechanical and Aerospace Engineering Department, Ithaca, NY. April 8, 2004.
Stanford University, Departments of Bioengineering and Mechanical Engineering, Stanford, CA. March 5, 2004.
University of California at Davis, Mechanical and Aeronautical Engineering Dept., Davis, CA, March 4, 2004.
National Institutes of Health, Rehabilitation Medicine Department, Bethesda, MD. December 12, 2003.
Johns Hopkins School of Medicine, Orthopaedic Biomechanics Lab, Baltimore, MD. December 11, 2003.
University of Tennessee, Mechanical Engineering Department, Knoxville, TN. October 30, 2003.
University of South Florida, Mechanical Engineering Department, Tampa, FL. March 4, 2003.
Colorado State University, Mechanical Engineering Department, Ft. Collins, CO. November 22, 2002.
Smith & Nephew Orthopedics, Research Division, Memphis, TN. May 1, 2002.
SERVICE ACTIVITIES
Department of Mechanical & Aerospace Engineering
1999-2002 Member, Biomechanics Minor Curriculum Ad Hoc Committee
1999-2004 Member, Dynamics PhD Qualifying Exam Ad Hoc Committee
Department of Biomedical Engineering
2003-2004 Member, Facilities/Web Committee
2003-2004 Coordinator, Graduate Student Recruitment Weekend
College of Engineering
200-2002 Graduation Marshall
2001 Grant Reviewer, Research Opportunity Fund

Benjamin J. Fregly 6
GRADUATE STUDENT SUPERVISION
Role Student Research Topic Dept Grad Date
Chair, Ph.D.
Committee
Bei, Y.
Dynamic simulation of knee joint contact during
human movement
AE Dec 2003
Dong, Z. Virtual prototyping of artificial knees ME May 2006*
Reinbolt, J. A.
Patient-specific musculoskeletal models for
predicting post-treatment functional outcome
ME May 2006*
Co-Chair, Ph.D.
Committee
Koh, B.-I.
Parallel algorithms for biomechanical
optimization problems
ECE May 2005*
Schutte, J. F.
Decomposition and optimization of large scale
systems with the particle swarm algorithm
AE May 2005*
Chair, M.S.
Committee
Bei, Y.
Multibody contact model formulations for
simulating human joints
AE Dec 2001
Dy-Liacco, I. A.
Creation of kinematic models of human
movement from video motion data
BME Aug 2001
Goede, T. E
Quantification of patellofemoral osteoarthritis
severity using high field-strength MRI
BME Dec 2001
Lin, Y.-C.
Experimental evaluation of a natural knee
contact model using response surface
optimization
ME Aug 2004
McDowell, M.
Piezoresistive sensor equilibration for contact
pressure measurements
ME May 2005*
Prasad, P. R.
Determination of patient-specific inertial
parameters through two-level optimization
BME Aug 2002
Rahman, H. A.
Accurate measurement of three-dimensional
natural knee kinematics using single-plane
fluoroscopy
BME Aug 2004
Reinbolt, J. A.
Determination of patient-specific functional axes
through two-level optimization
BME Aug 2003
Rooney, K. L.
Human movement prediction using inverse
dynamic optimization
BME Dec 2004*
AE = Aerospace Eng., ME = Mechanical Eng., ECE = Electrical and Computer Eng., BME = Biomedical Eng.
* = Estimated graduation date

Benjamin J. Fregly 7
TEACHING EVALUATIONS
Instructor Evaluation (Mean)
Instructor Overall (Mean)
Term Course Dr. Fregly Dept CoE Course Dept CoE
Fall 1999 EGM 5430 4.64 3.87 3.93 4.73 3.90 3.97
Spring 2000 EGM 4590 4.61 3.85 3.97 4.71 3.87 4.01
Fall 2000 EGM 5430 4.21 3.96 3.95 4.36 3.98 3.99
Spring 2001 EGM 4590 4.83 3.89 3.96 4.91 3.92 4.01
Fall 2001 EGM 5430 4.79 4.04 4.20 4.82 4.05 4.26
Spring 2002 EGM 4590 4.70 3.73 3.93 4.79 3.72 3.96
Fall 2002 EGM 6341 4.24 4.10 4.18 4.31 4.16 4.22
Spring 2003 EGM 4590 4.69 3.72 3.90 4.82 3.70 3.92
Fall 2003 EML 5595 4.91 4.09 4.22 5.00 4.16 4.34
Spring 2004 EGM 4344 4.43 3.95 4.01 4.62 4.03 4.07
Scale:
5 = High, 1 = Low
Course Titles: EGM 5430 = Intermediate Dynamics (F99, F00, F01, F04) – Graduate
EGM 4590 = Biodynamics (S00, S01, S02, S03) - Undergraduate
EGM 6341 = Numerical Methods of Engineering Analysis I (F02) - Graduate
EML 5595 = Mechanics of the Human Locomotor system (F03) - Graduate
EGM 4344 = Introduction to Numerical Methods of Engineering Analysis (S04) - Undergraduate