BIORESORB® Macro Pore Augmentation material - Optident

BIORESORB ® Macro Pore 

Augmentation material


Augmentation material 


Helps 

create bone 

New micro and macro porous 99% ß-Tricalcium phosphate 

ceramics as bone regeneration material 

Non-autogenous bone 

replacement materials for 

guided bone regeneration 

find increasing acceptance. 

The development of these 

materials have been constantly 

adapted to the latest 

scientific knowledge, as they 

show clear advantages as 

compared to other materials. 

In the meantime, advancements 

have progressed 

to create a new patented 

process for the manufacture 

of porous materials which are 

very similar to bone.



Macro and micro pores 

Why Bioresorb 

Macro Pore? 

With Bioresorb Macro Pore 

you are applying a material 

which derives from pure 

synthetic chemicals. This 

pure-phase ß-Tricalcium 

phosphate (99%) shows a 

crystalline structure which 

has optimal biological 

properties and is 100% 

resorbable. The material 

can be easily applied by 

any dentist in all indication 

situations. 

• Synthetic materials have 

absolutely no remaining 

risk of transfer of possible 

bacteria or of foreign body 

rejection. 

• Important: There is no 

requirement for patient 

information. This saves a 

considerable amount of 

your time. 

• Record result: The macroporous 

material can be 

easily applied similar to 

autogenous bone 

• The structure of Bioresorb 

Macro Pore is similar to 

natural bone. Complete 

vascularization is 

guaranteed by the optimal 

interconnecting porosity 

• An extremely high 

immediate stability of the 

granules in the defect is 

secured 

Interconnecting porosity 

The open and interconnecting 

porosity of the granules 

enable bone growth over the 

complete osteon structures. In 

addition, the material shows 

an exceptional capillary 

suction property. 

Osteoconductive 

Bioresorb Macro Pore allows 

bone to directly grow into the 

interconnecting pores prior 

to the resorption process. 

Bioresorb Macro Pore 

functions as guidance for new 

bone formation. 

Biocompatible 

The high biocompatibility 

of ß-Tricalcium phosphate 

(ß-TCP) was documented 

in numerous studies. There 

were no unfavorable tissue 

reactions nor immunologic 

reactive rejections. Bioresorb 

Macro Pore displays a very 

high integration within the 

natural bone without any 

soft tissue encapsulation or 

pathological reactions. There 

was no evidence of osteoclast 

activity. 

Complete resorption 

The resorption rate of 

Bioresorb Macro Pore is 

similar to the rate of new bone 

growth. The resorption of the 

ß-TCP occurs simultaneously 

with the formation of new 

natural bone within the 

augmentation site, depending 

upon the regeneration 

dynamics. 

Insertion of implants 

immediately post-extraction 

The prospective success 

of the therapy is increased 

considerably by the application 

of Bioresorb Macro 

Pore after immediate implant 

insertion or if applied in an 

alveolar defect.



Traces 

of the 

truth 

The percentage of micropores 

of an average size of 5 µm and 

the percentage of macropores 

with an average size of 500 µm 

is 30 volume percent each. 

The size interval of the micropores 

is 0.5 – 10 µm, and that 

of the macropores is 50 – 700 

µm. The high porosity enhances 

an improved dynamic 

regeneration as compared 

to other bone augmentation 

materials. The homogenous 

structure of macro and micropores 

offers a high capillary 

function, and the considerably 

larger surface can be soaked 

with more blood particles and 

cells of osteogenous potential. 

The pore structure allows 

more room for vascularization 

than other augmentation 

materials and provides an 

improved nutrition of the 

regenerative material. The 

considerably larger surface 

offers more contact for 

cellular resorption, resulting 

in a shorter resorption time. 

The interconnecting micropore 

system of the granules 

and especially the macropores 

are connected by a 

collagenous fiber network, 

along with sufficient blood 

vessels. The collagenous 

fibers function as guidance 

for the vessels as well as 

the newly formed bone, this 

stimulating the direct apposition 

of bone on the surfaces



99% phase-free ß-Tricalcium phosphate ceramics 

A new generation of pure-phase bioresorbable ß-Tricalcium 

phosphate ceramics was created by an innovative manufacturing 

process. The material consists of an interconnecting 

porosity system with macro and micro pores. 

SEM magnification x 100 of Bioresorb Macro Pore 

SEM magnification x 10,000 of Bioresorb Macro Pore 

of the granules prior to the 

start of resorption. The macropores 

facilitate the ingrowth 

of bone into the material, the 

osteones grow into the upper 

layers of the bone augmentation 

material. The bone regeneration 

material Bioresorb 

Macro Pore is resorbed 

completely, simultaneously 

with new bone growth and 

allows an accelerated 

regeneration of the natural 

vital bone at the defect site. 

The new ß-Tricalcium phosphate 

ceramic material has 

osteoconductive properties 

based on the micro and 

macroporous structure which 

enable bone defects which 

would normally not heal in a 

sufficient way, to regenerate 

well in good bone quality so 

that an immediate or a later 

implant insertion is possible. 

Despite the high porosity, 

Bioresorb Macro Pore has an 

optimal improved stability 

and high resistance against 

abrasion. The phase-purity 

provides a stable structure 

and homogenous resorption 

ability in time under physio



With an increasing defect size 

the pace of bone regeneration 

decreases, since the regeneration 

process is not based on 

a linear reaction. Therefore, 

please note that the defects 

with a maximum volume of 

less than 1.5 cm require three 

months, defects with a size 

between 1.5 cm and 2.5 cm six 

months, and defects of more 

than 2.5 cm nine months for 

complete bony regeneration. 

Note 

Bioresorb Macro Pore should 

be used only by a dentist or 

physician who is familiar with 

oral implantology and augmentation 

techniques. It is recommended 

to use Bioresorb 

Macro Pore in a moist state. 

The mass of the individual 

granules adheres and allows 

an easier application into the 

defect than in dry state. For 

moistening, a sterile isotonic 

saline solution can be used, 

better is autogenous blood of 

the patient or blood plasma 

(PRP – platelet rich plasma). 

If there is a risk of infection, 

combine with antibiotics. If the 

defect is larger than 2 cm, we 

recommend to use a mixture 

of Bioresorb Macro Pore with 

autogenous bone if harvesting 

is anatomically possible. 

When applying the material, 

do not compress to save the 

interconnecting porosity, but 

spread evenly in the defect 

and fill completely. The 

granule sizes to be used is 

depending on the size of the 

defect. In general, the larger 

the defect, the larger the 

granule size. Once the bone 

defect has been densely filled 

up to the edges by using a 

spoon or spatula – depending 

on the size – the site is closed 

using the usual suture technique. 

The covering gingiva 

periost flap should achieve primary 

closure without 

tension so that no granules 

can be washed out. If primary 

closure is not possible, we 

recommend the use of a nonresorbably 

Cytoplast membrane, 

according to the situation 

and following the instructions 

for use for membrane technique. 

The augmented site 

should not be loaded during 

the initial healing phase (i.e. 

do not use temporary prostheses 

or bridges on temporary 

implants, etc.).



Granula sizes 

For each indication, Bioresorb Macro Pore is 

available in an optimal granule size: 

200 – 500 µm 

Periodontal defects and other 

defects of small size 

500 – 1000 µm 

for alveolar defects, small and 

medium size cysts 

1000 – 2000 µm 

for sinus lift of normal 

extension 

1400 – 3200 µm 

for augmentation of large 

cysts and extended sinus 

elevation 

Granule size Vial contents Order No. 

200 – 500 µm 1 x 0.5 ml 2105 

500 – 1000 µm 1 x 0.5 ml 5105 

1 x 1.0 ml 5110 

1 x 2.0 ml 5120 

1000 – 2000 µm 1 x 0.5 ml 10105 

1 x 1.0 ml 10110 

1 x 2.0 ml 10120 

Set 

200 – 500 µm 5 x 0.5 ml 2505 

500 – 1000 µm 5 x 0.5 ml 5505 

5 x 1.0 ml 5510 

5 x 2.0 ml 5520 

1000 – 2000 µm 5 x 0.5 ml 10505 

5 x 1.0 ml 10510 

5 x 2.0 ml 10520 

Sinus lift 

1400 – 3200 µm 1 x 1.0 ml 14110 

1 x 2.0 ml 14120


Sybron Implant Solutions 

A World of Implant Solutions 

The dental implant platform of Sybron Dental Specialties (SDS) 

brings together three (INNOVA – ORALTRONICS – ATTACHMENTS) 

organizations that have been leaders in implant manufacturing, 

design and development since the inception of implant dentistry. 

With our most respected, innovative implant systems – PITT-EASY ® , 

and ENDOPORE ® – we are giving you access to a world of implant 

solutions. 

BIOVISION GmbH 

Am Vogelherd 52 

98693 Illmenau 

Distributed by: 

Sybron Implant Solutions GmbH 

Julius-Bamberger-Straße 8a · 28279 Bremen · Germany 

Phone +49 421 43939-0 · Fax +49 421 443936 

www.sybronimplants.de · info@sybronimplants.de 

08-0336: 12/08

BIORESORB® Macro Pore Augmentation material - Optident

Create successful ePaper yourself

Delete template?

Save as template?