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O - Swisstransfusion

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Conclusions:<br />

• The increasing number of known ABO variants with non-deletional<br />

alleles raises the question of their clinical significance – especially in<br />

blood donors.<br />

• Transfusion of red cell units with the variant ABO alleles O03, Aw08,<br />

and Ax03 typed and transfused as group O,<br />

and Bw20 typed and transfused as group A<br />

did not boost anti-A and anti-B titers in blood group O/A recipients .<br />

• For these variants no donor referral because of missing or weak<br />

isoagglutinins seems to be necessary .

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