Cell-Based Assays for Hepatotoxicity:
Cell-Based Assays for Hepatotoxicity:
Cell-Based Assays for Hepatotoxicity:
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HCS222<br />
Detecting changes in neuron biomarkers due to toxins<br />
Neurons & astrocyte co-culture<br />
untreated (Control)<br />
blue = nuclei<br />
green = III-tubulin (neurons)<br />
red = GFAP (astrocytes)<br />
Neurons & astrocyte co-culture treated<br />
with H 2<br />
O 2<br />
(toxin)<br />
Significant damage to neurons<br />
blue = nuclei<br />
green = III-tubulin (neurons)<br />
red = GFAP (astrocytes)<br />
1mM H 2 O 2