Cell-Based Assays for Hepatotoxicity:
Cell-Based Assays for Hepatotoxicity: Cell-Based Assays for Hepatotoxicity:
from massbio.org
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13.02.2015
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HepG2 cells treated with Campothecin (24h) Cell count Oxidative stress DNA damage
HepG2 cells treated with Campothecin (30mins – 72h) Cell loss Cell Count Cell Number (n=2, well mean +/- SD) 30min 24hr 72hr 30 mins 24h 72h 1000 0 1.00E-06 1.00E-05 1.00E-04 1.00E-03 1.00E-02 1.00E-01 1.00E+00 1.00E+01 [Camptothecin, + control] (uM on log scale) Campothecin (uM)
- Page 1 and 2: Cell-Based Assays for Hepatotoxicit
- Page 3 and 4: Now: High Content Analysis Automate
- Page 5 and 6: Inability to accurately screen for
- Page 7 and 8: Development of a high content analy
- Page 9: Development of a high content analy
- Page 13 and 14: Development of high content analysi
- Page 15 and 16: Cellular Targets for Neurotoxicity
- Page 17 and 18: Assays for detecting toxicity in as
- Page 19 and 20: Detecting changes in neuronal and a
- Page 21 and 22: Assessment of toxin effects on syna
- Page 23 and 24: Preliminary data: comparison of HCA
- Page 25 and 26: Preliminary data: comparison of HCA
- Page 27 and 28: Summary Cell-based assays for hepat
HepG2 cells treated with Campothecin (24h)<br />
<strong>Cell</strong> count Oxidative stress DNA damage
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