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barcelona . spain - European Association for the Study of the Liver

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BARCELONA . SPAIN<br />

96 POSTGRADUATE COURSE SYLLABUS ALCOHOLIC LIVER DISEASE 97<br />

APRIL 18 - 19/2012 THE INTERNATIONAL LIVER CONGRESS TM 2012<br />

Figure 2: Metabolism <strong>of</strong> Chlordiazepoxide, Diazepam and Lorazepam.<br />

Figure 3: The Glasgow Modified Alcohol Withdrawal Score (GMAWS)<br />

Tremor<br />

0) No tremor<br />

1) On movement<br />

2) At rest<br />

Sweating<br />

0) No sweat visible<br />

1) Moist<br />

2) Drenching sweats<br />

Hallucination<br />

0) Not present<br />

1) Dissuadable<br />

2) Not dissuadable<br />

Orientation<br />

0) Orientated<br />

1) Vague, detatched<br />

2) Disorientated, no<br />

contact<br />

Agitation<br />

0) Calm<br />

1) Anxious<br />

2) Panicky<br />

Score<br />

Treatment<br />

Score: (Do not use scoring tool if patient intoxicated,<br />

must be at least 8 hours since last drink.)<br />

0: Repeat Score in 2 hours (Discontinue<br />

after scoring on 4 consecutive occasions,<br />

except if less than 48hrs after last drink)<br />

1 – 3: Give 10mg Diazepam:<br />

Repeat Score in 2 hours<br />

4 – 8: Give 20mg Diazepam:<br />

Repeat Score in 1 hour<br />

9 - 10: Give 20mg Diazepam:<br />

Repeat Score in 1 hour;<br />

discuss with medical staff<br />

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Reviews 2011; 6: CD008537.pub2. DOI:10.1002/14651858<br />

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Rogawski MA. Update on <strong>the</strong> neurobiology <strong>of</strong> alcohol withdrawal seizures.<br />

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