11.02.2015 Views

barcelona . spain - European Association for the Study of the Liver

barcelona . spain - European Association for the Study of the Liver

barcelona . spain - European Association for the Study of the Liver

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

BARCELONA . SPAIN<br />

76 POSTGRADUATE COURSE SYLLABUS ALCOHOLIC LIVER DISEASE 77<br />

APRIL 18 - 19/2012 THE INTERNATIONAL LIVER CONGRESS TM 2012<br />

ABUSE OR DEPENDENCE ASSESSING THE ALCOHOLIC<br />

PATIENT IN THE CLINIC<br />

Antoni Gual<br />

Barcelona, Spain<br />

E-mail: TGUAL@clinic.ub.es<br />

KEY POINTS<br />

• Alcohol is <strong>the</strong> most dangerous drug when self inflicted harm and harm to o<strong>the</strong>rs are considered,<br />

and is <strong>the</strong> second top risk factor <strong>for</strong> health in developed countries.<br />

• Europe is <strong>the</strong> region <strong>of</strong> <strong>the</strong> world with <strong>the</strong> highest alcohol consumption.<br />

• Hazardous and harmful drinking are defined taking <strong>the</strong> amounts drunk into account, and people<br />

experiencing alcohol related harm do not need to be alcoholics.<br />

• The new DSM V (to be released May 2013), will probably combine Abuse and Dependence in a<br />

single entity called alcohol use disorders (AUD) <strong>of</strong> graded severity.<br />

• The criteria that define AUD cover four different areas: biological processes, medical harm,<br />

behaviour and social & relational aspects. All <strong>of</strong> <strong>the</strong>m must be assessed carefully in alcoholic<br />

patients.<br />

• The assessment <strong>of</strong> AUD must be done in an empathic non judgmental attitude, and must include<br />

a careful examination <strong>of</strong> drinking patterns, and an evaluation <strong>of</strong> <strong>the</strong> bio-medical, behavioural<br />

and social consequences <strong>of</strong> AUD.<br />

INTRODUCTION<br />

According to recent studies (Nutt, 2010), alcohol is <strong>the</strong> most dangerous drug when self inflicted harm and<br />

harm to o<strong>the</strong>rs are considered. Despite this evidence, Europe continues to be <strong>the</strong> region <strong>of</strong> <strong>the</strong> world with<br />

highest alcohol consumption. The World Health Organization (WHO) places alcohol as <strong>the</strong> second top risk<br />

factor <strong>for</strong> health in developed countries. 9 % <strong>of</strong> <strong>the</strong> disability adjusted life years in Europe are attributable<br />

to alcohol.<br />

Figure 1<br />

There is general agreement in <strong>the</strong> scientific community that <strong>the</strong> magnitude <strong>of</strong> <strong>the</strong> problems created by<br />

alcoholic beverages to society deserves a public health approach. From <strong>the</strong> medical point <strong>of</strong> view, alcohol<br />

is related to no less than sixty diseases, and it is wll known from ancient times that <strong>the</strong> liver is one <strong>of</strong> <strong>the</strong><br />

most vulnerable targets.<br />

DEFINING HAZARDOUS & HARMFUL DRINKING<br />

Most <strong>of</strong> <strong>the</strong> people who drink alcoholic beverages do it at very low risk levels, but a relevant percentage <strong>of</strong><br />

<strong>the</strong> drinkers may be at risk or experience problems because <strong>of</strong> <strong>the</strong>ir drinking. According to WHO hazardous<br />

drinkers are defined as those whose level <strong>of</strong> consumption or pattern <strong>of</strong> drinking is likely to result in harm<br />

should present drinking habits persist (Babor et al. 1994). There is no standardized agreement <strong>for</strong> <strong>the</strong><br />

level <strong>of</strong> alcohol consumption that should be taken <strong>for</strong> hazardous drinking, and <strong>for</strong> many conditions any<br />

level <strong>of</strong> alcohol consumption can carry risk. A working definition <strong>of</strong> <strong>the</strong> WHO describes it as a regular<br />

average consumption <strong>of</strong> 20g-40g <strong>of</strong> alcohol a day <strong>for</strong> women and 40g 60g a day <strong>for</strong> men (Rehm et al. 2004).<br />

Harmful drinking is defined as .a pattern <strong>of</strong> drinking that causes damage to health, ei<strong>the</strong>r physical (such<br />

as liver cirrhosis) or mental. Based on <strong>the</strong> epidemiological data relating alcohol consumption to harm <strong>the</strong><br />

WHO defines operatively harmful alcohol consumption as a regular average consumption <strong>of</strong> more than 40g<br />

alcohol a day <strong>for</strong> women and more than 60g a day <strong>for</strong> men (Rehm et al 2004). Episodic heavy drinking is<br />

defined as a drinking occasion that includes consumption <strong>of</strong> at least 60g <strong>of</strong> alcohol, and it is considered a<br />

<strong>for</strong>m <strong>of</strong> hazardous drinking that quite <strong>of</strong>ten leads to harm.<br />

Hazardous and harmful drinking are defined taking <strong>the</strong> amounts drunk into account, and people experiencing<br />

alcohol related harm do not need to be alcoholics. The American Psychiatric <strong>Association</strong> (APA) uses <strong>the</strong><br />

term Alcohol Abuse, which is <strong>of</strong>ten used as a synonimous <strong>of</strong> hazardous and harmful drinking.<br />

DIAGNOSING ALCOHOL DEPENDENCE<br />

The diagnosis <strong>of</strong> alcohol abuse is mostly based on <strong>the</strong> amounts drunk and in <strong>the</strong> presence <strong>of</strong> harm. Instead,<br />

alcohol dependence is defined takiing into account <strong>the</strong> drinking patterns <strong>of</strong> <strong>the</strong> patient and <strong>the</strong> type <strong>of</strong><br />

relationship <strong>the</strong> patient has stablished with alcohol. The presence <strong>of</strong> tolerance, withdrawal signs and <strong>the</strong><br />

salience <strong>of</strong> drinking behaviour over o<strong>the</strong>r priorities (family, work, health) are key to stablish a diagnosis.<br />

Both <strong>the</strong> APA and <strong>the</strong> WHO have set very similar criteria to diagnose alcohol dependence (Figure 2), and<br />

in both cases <strong>the</strong> presence <strong>of</strong> 3 or more criteria during <strong>the</strong> last 12 months is taken as cut-<strong>of</strong>f to stablish <strong>the</strong><br />

diagnosis.<br />

As it can be seen in Figure 1 <strong>the</strong> criteria used by WHO and APA are pretty similar, and so it is quite likely<br />

that <strong>the</strong> new versions <strong>of</strong> ICD and DSM will merge in a common definition.<br />

Figure 2

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!