barcelona . spain - European Association for the Study of the Liver
barcelona . spain - European Association for the Study of the Liver
barcelona . spain - European Association for the Study of the Liver
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BARCELONA . SPAIN<br />
58 POSTGRADUATE COURSE SYLLABUS ALCOHOLIC LIVER DISEASE 59<br />
APRIL 18 - 19/2012 THE INTERNATIONAL LIVER CONGRESS TM 2012<br />
REFERENCES<br />
Lucey, M.R., Mathurin, P., and Morgan, T.R. 2009. Alcoholic hepatitis. N Engl J Med<br />
360:2758-2769.<br />
Gao, B., and Bataller, R. 2011. Alcoholic liver disease: pathogenesis and new <strong>the</strong>rapeutic targets.<br />
Gastroenterology 141:1572-1585.<br />
Sozio, M., and Crabb, D.W. 2008. Alcohol and lipid metabolism. Am J Physiol<br />
Endocrinol Metab 295:E10-16.<br />
Altamirano J, Miquel R, Katoonizadeh A, et al. Development and validation <strong>of</strong> a novel histological<br />
classification with prognostic value <strong>for</strong> alcoholic hepatitis. Hepatology 2011;54:968A.<br />
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Laleman W, et al. Effect <strong>of</strong> <strong>the</strong> molecular adsorbent recirculating system and Prome<strong>the</strong>us devices<br />
on sytemic haemodynamics and vasoactive agents in patients with acut-on-chronic alcoholic liver<br />
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nonalcoholic fatty liver disease. Am J Pathol 2003; 1301-1311<br />
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Wong et al. Sepsis in cirrhosis: report <strong>of</strong> <strong>the</strong> 7 th meeting <strong>of</strong> <strong>the</strong> International Ascites Club.<br />
Gut2005; 54;718-725<br />
NONINVASIVE TOOLS IN THE DIAGNOSIS OF ALD<br />
Sebastian Mueller<br />
Heidelberg, Germany<br />
E-mail: sebastian.mueller@urz.uni-heidelberg.de<br />
KEY POINTS<br />
• ALD is underestimated due to limitations in noninvasively screening <strong>for</strong> <strong>the</strong> disease.<br />
• Measurement <strong>of</strong> liver stiffness (LS) by transient elastography is now <strong>the</strong> method <strong>of</strong> choice<br />
to screen <strong>for</strong> alcoholic liver fibrosis/cirrhosis (F3/4 stage). Alternative tools such as acoustic<br />
radiation <strong>for</strong>ce imaging (ARFI) or magnetic resonance elastography (MRE) are under<br />
investigation.<br />
• Normal liver stiffness (
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