barcelona . spain - European Association for the Study of the Liver

BARCELONA . SPAIN
30 POSTGRADUATE COURSE SYLLABUS ALCOHOLIC LIVER DISEASE 31
APRIL 18 - 19/2012 THE INTERNATIONAL LIVER CONGRESS TM 2012
The factors that facilitate the development of hepatitis and cirrhosis are not well characterized. However,
impairment in the cellular stress defense mechanisms, (e.g. oxidative stress) (Fernandez-Checa and
Kaplowitz, 2005), or derailment of the balance of autocrine or paracrine mediators that are critical in
maintaining normal homeostatic conditions are documented. In addition, chronic alcohol consumption
is known to interfere with liver regeneration, which under normal conditions is a highly effective repair
mechanism unique to the liver that avoids scar tissue formation.
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