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barcelona . spain - European Association for the Study of the Liver

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BARCELONA . SPAIN<br />

20 POSTGRADUATE COURSE SYLLABUS ALCOHOLIC LIVER DISEASE 21<br />

APRIL 18 - 19/2012 THE INTERNATIONAL LIVER CONGRESS TM 2012<br />

attributable liver mortality. In nor<strong>the</strong>rn Europe, a combination <strong>of</strong> primarily economic and market factors have<br />

contributed to increased levels <strong>of</strong> total consumption and its associated harm, whilst in sou<strong>the</strong>rn Europe<br />

social changes and health awareness have contributed to <strong>the</strong> downward trend in alcohol-related liver<br />

deaths from previously very high levels. For many years mortality rates in Nor<strong>the</strong>rn and Sou<strong>the</strong>rn Europe<br />

looked to be converging, but have crossed over <strong>the</strong> trends are continuing. In <strong>the</strong> UK mortality rates and<br />

hospital admissions driven cheap alcohol continue to increase. Alcohol consumption in <strong>the</strong> WHO <strong>European</strong><br />

Health Region remains <strong>the</strong> highest in <strong>the</strong> world and emerging trends, such as those seen among young<br />

people in Italy, mean that policy action needs to be taken to ensure that <strong>the</strong> decrease in liver cirrhosis is<br />

maintained. In global terms, Europe’s alcohol control policies are still not proportionate to <strong>the</strong> level <strong>of</strong> overall<br />

harm from alcohol.<br />

Taxation policy emerged as a crucial lever impacting upon alcohol consumption. In both <strong>the</strong> UK and Finland<br />

lower tax rates have helped to contribute to making alcohol more af<strong>for</strong>dable. In an EU context <strong>the</strong> relaxation<br />

<strong>of</strong> restrictions in cross border trade has had very deleterious effects in terms <strong>of</strong> taxation, price and alcoholrelated<br />

ill health.<br />

The marketing activities <strong>of</strong> <strong>the</strong> alcohol industry and retailers have had a huge impact in young people.<br />

Self regulation in this respect has failed, and o<strong>the</strong>r mechanisms need to be explored. The UK House <strong>of</strong><br />

Commons Health Committee has recommended a fully independent regulatory authority to control alcohol<br />

marketing, and <strong>the</strong> EU would do well to examine <strong>the</strong>se proposals carefully.<br />

However <strong>the</strong> reduction in liver deaths in France has occurred alongside an increase in pr<strong>of</strong>itability <strong>of</strong> <strong>the</strong><br />

wine industry as a result <strong>of</strong> <strong>the</strong> industry model shifting from one based on quantity (<strong>the</strong> current UK model)<br />

to one based on quality, and here <strong>the</strong> EU in <strong>the</strong> <strong>for</strong>m <strong>of</strong> <strong>the</strong> common agricultural policy may have had a<br />

beneficial effect, driving down <strong>the</strong> amount <strong>of</strong> cheap alcohol that is produced in order to protect farmers.<br />

approaches are ineffective on <strong>the</strong> whole(4). The alcohol strategy has a number <strong>of</strong> components including <strong>the</strong><br />

EU Alcohol Forum, which again brings health and industry representatives toge<strong>the</strong>r in a <strong>for</strong>um <strong>for</strong> action.<br />

The EU liver community has been an active member <strong>of</strong> this <strong>for</strong>um via EASL and <strong>the</strong> RCP although o<strong>the</strong>r<br />

than a promising work stream on <strong>the</strong> monitoring <strong>of</strong> marketing communications, hard outcomes have been<br />

few and far between.<br />

In 2011 <strong>the</strong> EU alcohol strategy will need to be renewed, initial soundings from <strong>the</strong> Commissioner <strong>for</strong><br />

Health were not promising, but a recent meeting <strong>of</strong> member states <strong>of</strong>fered unanimous support <strong>for</strong> a new<br />

alcohol strategy which will be in<strong>for</strong>med by an independent evaluation <strong>of</strong> <strong>the</strong> previous five years work. The<br />

support <strong>of</strong> EASL and <strong>the</strong> EU liver community will be vital over <strong>the</strong> next year or so as this process moves<br />

<strong>for</strong>ward. The simple truth is that <strong>of</strong> <strong>the</strong> 200,000 alcohol related deaths in <strong>the</strong> EU every year, much due<br />

to liver disease, probably around two thirds are preventable if each country adopted effective policies to<br />

reduce alcohol related harm. The question <strong>for</strong> <strong>the</strong> liver community is: “how big is our ambition to tackle liver<br />

mortality and are we prepared to be advocates <strong>for</strong> <strong>the</strong> measures needed to achieve it”.<br />

Relationship between liver death rates and population level alcohol consumption<br />

Figure 1<br />

The relationship between standard liver death rates (per 100,000) and overall alcohol consumption (pure<br />

alcohol litres per capita, age 15+) in <strong>the</strong> 4 countries in <strong>the</strong> EU (pre 2004) with <strong>the</strong> largest rises or falls in<br />

liver deaths between 1970 and 2008. Data is from <strong>the</strong> World Health Organisation, <strong>European</strong> Health <strong>for</strong> All<br />

database (HFA-DB): http://data.euro.who.int/hfadb/<br />

Given <strong>the</strong> tight relationship between death rates and consumption, a reduction on <strong>the</strong> overall %ABV <strong>of</strong><br />

alcoholic beverages is ano<strong>the</strong>r mechanism whereby consumption can be reduced but pr<strong>of</strong>itability <strong>of</strong> <strong>the</strong><br />

wine industry maintained or indeed increased. For example wine at 8.5% ABV is taxed at <strong>the</strong> same level as<br />

wine at 14% ABV under EU law – a nonsensical system that benefits nei<strong>the</strong>r consumer nor industry.<br />

Current alcohol policy in Europe<br />

Alcohol policy in Europe has two streams, at member state level <strong>the</strong> picture is mixed. Some countries,<br />

notably France, have developed outstanding examples <strong>of</strong> inventive and effective evidence based alcohol<br />

policy, <strong>for</strong> example <strong>the</strong> Loi Evin which has protected young people from <strong>the</strong> marketing pressures <strong>of</strong> <strong>the</strong><br />

drinks industry. O<strong>the</strong>r countries, notably <strong>the</strong> UK, have effectively transferred large segments <strong>of</strong> alcohol policy<br />

to <strong>the</strong> vested interests <strong>of</strong> <strong>the</strong> drinks industry via <strong>the</strong> ‘Responsibility Deals’. These are bodies comprising<br />

representatives <strong>of</strong> <strong>the</strong> alcohol, food and retail industries which aim to introduce voluntary measures to curb<br />

alcohol related harm. This untested approach has drawn approbation from <strong>the</strong> health community in <strong>the</strong> UK<br />

who refused to sign <strong>the</strong> relevant agreements in 2010.<br />

The EU Commission alcohol strategy commenced in 2006, and has five priority areas:<br />

• Protect young people, children and <strong>the</strong> unborn child;<br />

• Reduce injuries and death from alcohol-related road accidents;<br />

• Prevent alcohol-related harm among adults and reduce <strong>the</strong> negative impact on <strong>the</strong><br />

workplace;<br />

• In<strong>for</strong>m, educate and raise awareness on <strong>the</strong> impact <strong>of</strong> harmful and hazardous alcohol<br />

consumption, and on appropriate consumption patterns;<br />

• Develop and maintain a common evidence base at EU level.<br />

Political imperatives and <strong>the</strong> subsidiarity <strong>of</strong> EU taxation has meant that <strong>the</strong> Commission has also been<br />

heavily reliant on voluntary actions and self regulation by <strong>the</strong> drinks industry despite <strong>the</strong> evidence that such

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