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barcelona . spain - European Association for the Study of the Liver

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BARCELONA . SPAIN<br />

14 POSTGRADUATE COURSE SYLLABUS ALCOHOLIC LIVER DISEASE 15<br />

APRIL 18 - 19/2012 THE INTERNATIONAL LIVER CONGRESS TM 2012<br />

Also, reduction <strong>of</strong> <strong>the</strong> hours or days <strong>of</strong> sale leads to fewer alcohol-related problems. However, <strong>the</strong>re is<br />

evidence that strict restriction can lead to illicit market. Pricing policies have very well demonstrated an<br />

inverse correlation between alcohol price and consumption. A recent report commissioned by <strong>the</strong> EU,<br />

concluded that <strong>the</strong>re is a positive relationship between alcohol af<strong>for</strong>dability and alcohol consumption, and<br />

also between alcohol consumption and 3 types <strong>of</strong> harms: traffic injuries, traffic deaths, and liver cirrhosis.<br />

The report also concludes that cross-border alcohol consumption due to tax differentials can lead to<br />

increases in consumption.<br />

Figure 1<br />

Alcohol-attributable deaths as proportion <strong>of</strong> all deaths by sex in Europe and World. Data from WHO Global<br />

Burden 2004.<br />

Undoubtedly, increasing alcohol taxes reduces alcohol consumption and related harm and increases<br />

government revenue. The effect tends to be stronger in <strong>the</strong> long term, delaying <strong>the</strong> start <strong>of</strong> drinking, and<br />

slowing young people’s progression to heavy drinking. It also reduces young people heavy drinking and <strong>the</strong><br />

volume <strong>of</strong> alcohol per occasion, and has a much stronger effect on heavier than on light drinkers.<br />

Also, alcohol marketing has a major impact in levels and patterns <strong>of</strong> consumption, especially in young<br />

people. In fact, <strong>the</strong>re is an impressive sophisticated advertising in mainstream media. Powerful marketing<br />

campaigns link alcohol brands to sports and cultural activities, through sponsorships, internet, podcasting<br />

and mobile phones. It has been shown that exposure to alcohol advertising has an effect on initiation <strong>of</strong><br />

young drinking and on riskier patterns <strong>of</strong> youth drinking in 13 longitudinal studies including 38,000 young<br />

people. Fur<strong>the</strong>rmore, young people likely continue to increase <strong>the</strong>ir drinking as <strong>the</strong>y move in <strong>the</strong>ir twenties.<br />

Also, <strong>the</strong> effects <strong>of</strong> exposure are cumulative. Individuals with higher consumptions in <strong>the</strong>ir mid-teens tend to<br />

be those with heavier consumption, alcohol dependence and alcohol-related harm, including poorer mental<br />

health and education outcome, and increased risk <strong>of</strong> crime, in early adulthood.<br />

REFERENCES<br />

WHO. Global Status Report on Alcohol 2004. Geneva: World Health Organization; 2004.<br />

Rehm J, Ma<strong>the</strong>rs C, Popova S, Thavorncharoensap M, Teerawattananon Y, Patra J. Global<br />

burden <strong>of</strong> disease and injury and economic cost attributable to alcohol use and<br />

alcohol-use disorders. Lancet 2009;373:2223-33. *<br />

Stuckler D, Basu S, Suhrcke M, Coutts A, McKee M. The public health effect <strong>of</strong> economic crises<br />

and alternative policy responses in Europe: an empirical analysis. Lancet 2009;374:315-23.<br />

Roulot D, Costes JL, Buyck JF, Warzocha U, Gambier N, Czernichow S, Le Clesiau H,<br />

Beaugrand M. Transient elastography as a screening tool <strong>for</strong> liver fibrosis and cirrhosis in a<br />

community-based population aged over 45 years. Gut 2011;60:977-84.<br />

WHO. <strong>European</strong> Status Report on Alcohol and Health 2010. Copenhagen; 2010.<br />

Burra P, Senzolo M, Adam R, Delvart V, Karam V, Germani G, Neuberger J. <strong>Liver</strong> transplantation<br />

<strong>for</strong> alcoholic liver disease in Europe: a study from <strong>the</strong> ELTR (<strong>European</strong> <strong>Liver</strong> Transplant Registry).<br />

Am J Transplant 2010;10:138-48.<br />

Mathurin P, Deltenre P. Effect <strong>of</strong> binge drinking on <strong>the</strong> liver: an alarming public health issue Gut<br />

2009;58:613-7.<br />

Rabinovich L, Brutscher P-B, Vries H, Tiessen J, Clift J, Reding A. The af<strong>for</strong>dability <strong>of</strong> alcoholic<br />

beverages in <strong>the</strong> <strong>European</strong> Union. Understanding <strong>the</strong> link between alcohol af<strong>for</strong>dability,<br />

consumption and harms; 2009.<br />

Rehm J, Taylor B, Mohapatra S, Irving H, Baliunas D, Patra J, Roerecke M. Alcohol as<br />

a risk factor <strong>for</strong> liver cirrhosis: a systematic review and meta-analysis. Drug Alcohol<br />

Rev 2010;29:437-45*<br />

Anderson P, Chisholm D, Fuhr DC. Effectiveness and cost-effectiveness <strong>of</strong> policies and<br />

programmes to reduce <strong>the</strong> harm caused by alcohol. Lancet 2009;373:2234-46.<br />

Figure 2<br />

Alcohol-attributable disability adjusted life years (DALYs) as proportion <strong>of</strong> all DALYs by sex in Europe and<br />

World. Data from WHO Global Burden 2004.

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