Faculty of Pharmacy

Parenteral solutions (osmoses, diffusion and dialyze, isotonic and isohidri, parenteral production
technology, filtration and ultra filtration, sterilization), eye, nose and ear drops, stability of drugs and
reaction kinetics, incompatibility, biopharmaceutics and pharmacokinetics, radiopharmaceuticals.
(ECZ491) PHARMACEUTICAL TECHNOLOGY PRACTICE III (P)
HOUR/WEEK :4, ECTS:2
Carbomedicinalis package, eutectic mixtures, granules and effervescent granules, investigations of
particle size distribution and flow properties of granules, capsule production, physical controls in
capsules, tablets and their controls, gelatin lozonage, aerosol production and controls, prescription
practices subjects are investigated.
(ECZ488) PHARMACEUTICAL TECHNOLOGY PRACTICE IV (P)
HOUR/WEEK :4, ECTS:4
Parenteral solutions, drops (eye, nose and ear drops), sterile neutral olive oil, stability test for aspirin,
incompatible prescriptions, in vitro dissolution test for solid dosage forms, industrial production for
syrups, emulsions and ointments and prescription practices are investigated.
(ECZ493) PHARMACEUTICAL TOXICOLOGY THEORY I (T)
HOUR /WEEK :2, ECTS:3
General information about toxicology and poisons; Entrance ways and absorption of poisons;
Metabolism of toxic substances; Toxicokinetics; Mechanisms of toxic effects; Genetic toxicology;
Chemical mutagenesis; Chemical carcinogenesis Teratogenesis; Systemic toxicology; Investigation of
toxicity and risk analyses; First aid in acute poisonings and principles of antidote treatment.
(ECZ490) PHARMACEUTICAL TOXICOLOGY THEORY II (T)
HOUR/WEEK :2, ECTS:3
Drug toxicity; Drug interactions; Drug abuse and dependence; Pesticides; Airborne poisons; Organic
solvents; Metallic poisons; Radiation and radioisotopes; Natural poisons; Poisons of plant and animal
origin.
(ECZ495) PHARMACEUTICAL TOXICOLOGY PRACTICE I (P)
HOUR/WEEK :2, ECTS:2
Aim and general information; Phase I (EROD and cotinine) tests; Isolation and current use of genomic
DNA molecule from biological samples; Genotyping 1 (gene deletion, GSTM 1, GSTT1), Genotyping 2
(SNP, GSTP1); Genotyping 3 (cut product); Genotoxicity tests used to identify chromosomal damage
[Sister Chromatid Exchange (SCE) and micronucleus test (MN)]; Indication of potential antioxidant
substances (DPPH, glutathione); Lipid peroxidation; Cytotoxicity; Investigation of acute toxicity;
Evaluation of teratogenic effects of chemical substances using inseminated chicken embryo.
(ECZ492) PHARMACEUTICAL TOXICOLOGY PRACTICE II (P)