Faculty of Pharmacy
Faculty of Pharmacy
Faculty of Pharmacy
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Parenteral solutions (osmoses, diffusion and dialyze, isotonic and isohidri, parenteral production<br />
technology, filtration and ultra filtration, sterilization), eye, nose and ear drops, stability <strong>of</strong> drugs and<br />
reaction kinetics, incompatibility, biopharmaceutics and pharmacokinetics, radiopharmaceuticals.<br />
(ECZ491) PHARMACEUTICAL TECHNOLOGY PRACTICE III (P)<br />
HOUR/WEEK :4, ECTS:2<br />
Carbomedicinalis package, eutectic mixtures, granules and effervescent granules, investigations <strong>of</strong><br />
particle size distribution and flow properties <strong>of</strong> granules, capsule production, physical controls in<br />
capsules, tablets and their controls, gelatin lozonage, aerosol production and controls, prescription<br />
practices subjects are investigated.<br />
(ECZ488) PHARMACEUTICAL TECHNOLOGY PRACTICE IV (P)<br />
HOUR/WEEK :4, ECTS:4<br />
Parenteral solutions, drops (eye, nose and ear drops), sterile neutral olive oil, stability test for aspirin,<br />
incompatible prescriptions, in vitro dissolution test for solid dosage forms, industrial production for<br />
syrups, emulsions and ointments and prescription practices are investigated.<br />
(ECZ493) PHARMACEUTICAL TOXICOLOGY THEORY I (T)<br />
HOUR /WEEK :2, ECTS:3<br />
General information about toxicology and poisons; Entrance ways and absorption <strong>of</strong> poisons;<br />
Metabolism <strong>of</strong> toxic substances; Toxicokinetics; Mechanisms <strong>of</strong> toxic effects; Genetic toxicology;<br />
Chemical mutagenesis; Chemical carcinogenesis Teratogenesis; Systemic toxicology; Investigation <strong>of</strong><br />
toxicity and risk analyses; First aid in acute poisonings and principles <strong>of</strong> antidote treatment.<br />
(ECZ490) PHARMACEUTICAL TOXICOLOGY THEORY II (T)<br />
HOUR/WEEK :2, ECTS:3<br />
Drug toxicity; Drug interactions; Drug abuse and dependence; Pesticides; Airborne poisons; Organic<br />
solvents; Metallic poisons; Radiation and radioisotopes; Natural poisons; Poisons <strong>of</strong> plant and animal<br />
origin.<br />
(ECZ495) PHARMACEUTICAL TOXICOLOGY PRACTICE I (P)<br />
HOUR/WEEK :2, ECTS:2<br />
Aim and general information; Phase I (EROD and cotinine) tests; Isolation and current use <strong>of</strong> genomic<br />
DNA molecule from biological samples; Genotyping 1 (gene deletion, GSTM 1, GSTT1), Genotyping 2<br />
(SNP, GSTP1); Genotyping 3 (cut product); Genotoxicity tests used to identify chromosomal damage<br />
[Sister Chromatid Exchange (SCE) and micronucleus test (MN)]; Indication <strong>of</strong> potential antioxidant<br />
substances (DPPH, glutathione); Lipid peroxidation; Cytotoxicity; Investigation <strong>of</strong> acute toxicity;<br />
Evaluation <strong>of</strong> teratogenic effects <strong>of</strong> chemical substances using inseminated chicken embryo.<br />
(ECZ492) PHARMACEUTICAL TOXICOLOGY PRACTICE II (P)