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Faculty of Pharmacy

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Pathophysiology <strong>of</strong> diseases: Hypertension, heart failure-shock, arrhythmia, atherosclerotic heart<br />

disease, peptic ulcer, inflammated bowel diseases, liver diseases, constipation and diarrhea, gout,<br />

inflammation and Immunity, acute and chronic renal failure, Iymphoma, leukemia, rheumatoid<br />

arthritis, osteoporosis, thyroid gland diseases, diabetes mellitus, chronic obstructive pulmonary<br />

disease, tuberculosis. Definition and mechanisms <strong>of</strong> inflammation, hypoxia, ischemia, cyanosis.<br />

Regulation <strong>of</strong> body temperature and pathophysiology <strong>of</strong> fever. Definition, mechanism and types <strong>of</strong><br />

pain. Vascular fluid regulation, pathophysiology <strong>of</strong> edema, clinical types <strong>of</strong> edema. Fluid-electrolyte<br />

balance and disturbances, hypervolemia and hypovolemia. Acid-base balance and disturbances.<br />

Kidney function disturbances. Kidney failure. Atherosclerosis, coronary artery diseases, myocard<br />

infarction pathophysiology. Definition <strong>of</strong> hypertension, Causes <strong>of</strong> primary and secondary<br />

hypertension, mechanisms and complications. Mechanisms <strong>of</strong> heart failure, left and right heart<br />

failure, pulmonary hypertension. Definition <strong>of</strong> shock, pathophysology, causes and types <strong>of</strong> shock.<br />

Causes <strong>of</strong> obstructive and restrictive respiratory diseases. Pathophysiology <strong>of</strong> allergy, anaflaxia and<br />

asthma. Mechanisms <strong>of</strong> hypothalamus-hypophysis axis disorders. Pathophysiology <strong>of</strong><br />

hyperthyroidism and hypothyroidism. Bone and mineral metabolism and disorders. Disorders <strong>of</strong><br />

blood glucose regulation: hyperglycemia and hypoglycemia. Pathophysiology and complications <strong>of</strong><br />

peptic ulcer. Causes and mechanisms <strong>of</strong> diarrhea and constipation. Disorders <strong>of</strong> gall bladder and bile<br />

duct, causes <strong>of</strong> jaundice. Liver function disorders. Liver failure and hepatitis. Definition, mechanisms,<br />

reasons and types <strong>of</strong> anemia. White blood cell disorders, leucopenia, leukocytosis, leukomoid<br />

reaction, lymphoma and leukemias. Disorders <strong>of</strong> homeostatic regulation I: Vascular and coagulation<br />

disorders. Disorders <strong>of</strong> homeostatic regulation II: Thrombocyte disorders and disseminated<br />

intravascular coagulation. Autoimmune and collagen tissue disorders.<br />

(ECZ481) PHARMACOGNOSY III (T)<br />

HOUR/WEK :2, ECTS :3<br />

Definition <strong>of</strong> alkaloids distribution in plant kingdom will be described. Classification, botanical source,<br />

pharmacological activity and uses <strong>of</strong> alkaloids will be given. Further information will be mentioned<br />

about isolation, identification and analysis <strong>of</strong> these active alkaloidal substances. Information on<br />

enzymes, protits, vaccines and serums also will be given.<br />

(ECZ483) PHARMACOGNOSY III PRACTICE (P)<br />

HOUR/WEEK :4, ECTS:3<br />

Microscopic characters, identification, isolation, pharmacopeial analysis, qualitative and quantitative<br />

analysis <strong>of</strong> the drugs containing alkaloid substances will be given experimentally.<br />

(ECZ485) PHARMACEUTICAL CHEMISTRY III (T)<br />

HOUR/WEEK :2, ECTS:2<br />

The mission <strong>of</strong> the Pharmaceutical Chemistry III course is to introduce students to the chemical<br />

formula, general physico-chemical and structural properties, synthesis, chemistry <strong>of</strong> metabolites<br />

structure-activity relationships <strong>of</strong> pharmaceutical agent. Topics include Cholinergic drugs: 1.<br />

Parasympathomimetics, 2. Anti-cholinesterase drugs, Neuromuscular blocking drugs, ganglion

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