Biotechnology Research Roadmap - Science and Innovation
Biotechnology Research Roadmap - Science and Innovation
Biotechnology Research Roadmap - Science and Innovation
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2.3 Future outlook 15 • cleaner, more efficient biofuels;<br />
Recent <strong>and</strong> continuing advances in the life sciences<br />
have led to an oft-cited assertion that the 21st Century<br />
will be the “biotechnology century”. 16<br />
A wide range of biotechnology R&D activities are<br />
maturing at a rapid pace. Over the next twenty years<br />
these are projected to significantly affect the healthcare<br />
<strong>and</strong> primary production sectors <strong>and</strong> contribute to more<br />
sustainable manufacturing processes <strong>and</strong> industrial<br />
products.<br />
Outcomes predicted include:<br />
• healthcare technologies drawing on genetics,<br />
genomics, <strong>and</strong> proteomics that promise better,<br />
more personalised health outcomes;<br />
• regenerative cell therapies fuelled by advances in<br />
stem cell research;<br />
• more sustainable <strong>and</strong> value-added food <strong>and</strong> fibre<br />
production systems;<br />
• enzymatic processing in manufacturing that cuts<br />
energy <strong>and</strong> water consumption <strong>and</strong> the generation<br />
of toxic wastes; <strong>and</strong><br />
• the production of novel biomaterials for medical<br />
<strong>and</strong> industrial purposes. 17<br />
Emerging biotechnology developments are being<br />
influenced by a range of drivers. These include:<br />
• demographic trends such as longer life<br />
expectancies (especially in developed countries),<br />
decreased fertility <strong>and</strong> delayed reproduction, <strong>and</strong><br />
increased consumer dem<strong>and</strong> for the medical<br />
“treatment” of non-pathological “disorders”; <strong>and</strong><br />
• sustainability drivers spurred by the need to<br />
respond to issues like climate change <strong>and</strong> fossil fuel<br />
dependency.<br />
2.4 Market trends<br />
Each of the key biotechnology sectors – health,<br />
agricultural <strong>and</strong> industrial biotechnology<br />
– are currently all at differing stages of maturity.<br />
As a result, areas such as the commercialisation of<br />
biopharmaceuticals have a clear pathway to market,<br />
whereas routes to market are less well characterised for<br />
industrial <strong>and</strong> environmental biotechnology because<br />
of their earlier stage of development.<br />
2.4.1 Health biotechnology<br />
The most mature global biotechnology market is<br />
currently the healthcare sector. In fact, growth in this<br />
market has underpinned the sustained growth of the<br />
whole global biotechnology industry to date.<br />
Ninety percent of current global value from<br />
biotechnology is derived from biopharmaceuticals<br />
alone <strong>and</strong> the vast majority of biotechnology firms are<br />
working across this broad field. Fifteen percent of all<br />
drugs are currently based on biotechnology <strong>and</strong> this is<br />
projected to grow to 40 percent by 2010.<br />
To add weight to this projection, more than 30 percent<br />
of drugs currently in development are biological. 18<br />
Beyond the projected biological drug “pipeline”,<br />
rapid advances in both stem cell research <strong>and</strong><br />
the neurosciences are driving developments in<br />
regenerative medicine. There is still, however,<br />
much basic research to be performed to underst<strong>and</strong><br />
the underlying biology of areas such as stem cell<br />
science, not to mention many ethical issues which are<br />
accompanying developments.<br />
15<br />
For a more in-depth summary of future biotechnology issues <strong>and</strong> trends see: MoRST (2005), Futurewatch: Biotechnologies to 2025: http://www.morst.govt.nz/currentwork/futurewatch/biotechnologies-to-2025/<br />
16<br />
Rifkin, J (1998), The Biotech Century<br />
17<br />
OECD (2005), The Bioeconomy in 2030<br />
18<br />
OECD (2004), The Economic Impacts of <strong>Biotechnology</strong> – An Introduction – Working paper of National Experts on <strong>Science</strong> <strong>and</strong> Technology Indicators, DSTI/EAS/STP/<br />
NETI(2004), p.6<br />
<strong>Roadmap</strong>s for <strong>Science</strong> : biotechnology research<br />
11